Navigation Links
Human Stem Cell Transplant Helps Brain-Impaired Mice
Date:6/4/2008

Restored damaged electrical pathway seen in MS patients who lose nerve signals

WEDNESDAY, June 4 (HealthDay News) -- Mice with a congenital brain disorder improved after receiving human neural stem cell transplants, a U.S. study finds.

The mice lacked myelin, a substance that plays a critical role in the transmission of electrical signals between nerve cells. When myelin is missing or damaged, electrical signals aren't properly transmitted. These "shiverer" mice typically die within months of birth.

Demyelination also occurs in people with multiple sclerosis.

Previous research has examined the use of cell transplantation for restoring absent or lost myelin to diseased nerve fibers. But, until now, no transplantation of human neural stem cells or of their derivatives (glial progenitor cells) had been successful in test animals.

In this new study, researchers from the University of Rochester Medical Center and a number of other universities (Cornell, UCLA and Baylor) created a new method for harvesting and purification of human fetal glial progenitor cells.

They also developed a new cell delivery strategy that uses multiple injection sites to encourage widespread and dense take-up of the transplanted cells through the central nervous system.

When the researchers used these new approaches, the transplanted cells took hold throughout the brain and spinal cord, and the mice showed robust, efficient and functional myelination. Some of the mice showed neurological improvement and a fraction of them were save by the procedure.

"The neurological recovery and survival of the mice receiving transplants was in sharp contrast to the fate of their untreated controls, which uniformly died by five months," researcher Dr. Steve Goldman, of the departments of neurology and neurosurgery at the University of Rochester Medical Center, said in a prepared statement.

"To our knowledge, the
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Public funding impacts progress of human embryonic stem cell research
2. Virginia Tech researchers find human virus in chimpanzees
3. How defects in 1 gene cause 3 distinct and devastating human diseases
4. New method identifies rat poison in humans
5. Best Practice Database Optimizes Human Resource Management
6. TU Delft robot Flame walks like a human
7. A potential route for human tumor gene therapy
8. Project HOPE to Send Humanitarian Assistance to China as Humanitarian Assistance to Myanmar Continues
9. New Therapy Kills Human Leukemia Cells in Mice
10. Human Pheromone Sciences Announces First Quarter Results
11. Researchers find first conclusive evidence of Alzheimers-like brain tangles in nonhuman primates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... NY (PRWEB) October 20, 2014 ... non-profit organization that helps New Yorkers living with ... changes toward health, housing, recovery and self-sufficiency. Each ... transformed the local community through their tireless efforts. ... Marc Shapses , has been selected as ...
(Date:10/20/2014)... CA (PRWEB) October 20, 2014 JZ ... expertise, nutritional coaching, corporate wellness programming, authorship, international lecturing ... is excited to announce the release of the JZ ... After many years of coaching thousands of individuals on ... tracking app that does not require calorie counting or ...
(Date:10/20/2014)... 20, 2014 Rockynol Retirement Community ... on Oct. 14. The $11 million project will include ... a cooked-to-order kitchen with full-service restaurant style dining. , ... for first class Assisted Living apartments,” said Kara Hanzie, ... the highest quality of care and this investment is ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Unveiled at the ... Strategic Direction Scorecard conservatively estimates member hospital ROI on membership ... on dues, The Center provides $12.50 in value to member ... (Member Value – Member Dues)/Member Dues. , “This is ... this number and we think the methodology is really sound,” ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 Hastings and ... 30 years of service throughout the greater Phoenix area ... legal representation with regard to catastrophic automobile accidents. Statistics ... the country and throughout Arizona. As such, Hastings and ... for legal representation for those who have been injured ...
Breaking Medicine News(10 mins):Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 2Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 3Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3Health News:Rockynol Retirement Community Expands Assisted Living Center 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 3Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 4Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 2Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 3
... suffering from posttraumatic stress disorder (PTSD) are as likely ... disease risk factors such as an elevated white blood ... healthcare providers screen for PTSD in the same way ... , Exposure to trauma has not only psychological effects, ...
... Name ... Same Commitment to ... the Health of all Babies, CINCINNATI, Feb. ... that 4-year-old Bradley,Coffey of Kennedy Heights and his family will serve as ... WalkAmerica,March for Babies is the March of Dimes premier fundraising event that,benefits ...
... /PRNewswire-FirstCall/ - LMS Medical Systems (TSX:,LMZ, AMEX: LMZ), ... information system and risk management software tools for,obstetrics, ... third,quarter ended December 31, 2007. All amounts are ... new installations and growing recurring maintenance,and technical service ...
... Briefing on Feb. 12, WASHINGTON, Feb. ... a significant role in preparing federal legislation,received ... groups. The American Society of Transplantation (AST), ... Organ Sharing (UNOS),and Association of Organ Procurement ...
... (Nasdaq: DYNT ) will release financial results ... February 14, 2008., Dynatronics has scheduled a ... p.m. ET to discuss its results for the ... should call 800-839-9416 and use,passcode: 1383812., Dynatronics ...
... Gen-Probe Incorporated,(Nasdaq: GPRO ) announced today that ... Mid-Cap Growth Conference on Friday, February 15,2008 at approximately ... is scheduled to be webcast live and may be ... . The webcast will,be available for 30 days following ...
Cached Medicine News:Health News:Geisinger study: PTSD a medical warning sign for long-term health problems 2Health News:Local Families Chosen for Ambassador Role for 2008 March for Babies 2Health News:Local Families Chosen for Ambassador Role for 2008 March for Babies 3Health News:LMS Third Quarter 2008 Financial Results - Q3 Revenue Increases 88% to $1.0 Million - YTD Revenue Increases 87% to $2.6 Million 2Health News:LMS Third Quarter 2008 Financial Results - Q3 Revenue Increases 88% to $1.0 Million - YTD Revenue Increases 87% to $2.6 Million 3Health News:LMS Third Quarter 2008 Financial Results - Q3 Revenue Increases 88% to $1.0 Million - YTD Revenue Increases 87% to $2.6 Million 4Health News:Transplant Community Unites to Educate Capitol Hill Staffers About the 'Gift of Life' 2Health News:Gen-Probe to Webcast Presentation at Deutsche Bank Small- and Mid-Cap Growth Conference 2
(Date:10/19/2014)... , Deutschland, October 19, 2014 ... gefragt. Das Problem dabei ist, dass ... mit der Kompetenz zu teilen. Es ... deshalb freuen wir uns umso mehr, dass es ... ihre Gepflogenheiten bei Kühlketten aufzuschreiben - mit einem ...
(Date:10/17/2014)... , Oct. 17, 2014 With ... Medical Affairs function has come across several challenges ... efficiently and managing globalization.  The ... LLC is dedicated to providing benchmarking and best ... Affairs Consortium is a service composed of three ...
(Date:10/17/2014)... -- Hanger, Inc. (NYSE: HGR ) announced today ... for the quarter ended September 30, 2014, on Thursday, ... call to discuss these results is scheduled to begin ... Those wishing to participate should call 1-877-662-6095. A replay ... dialing 1-855-859-2056 and referencing Conference ID # 91880739. ...
Breaking Medicine Technology:Vergleichsbericht zu Pharma-Kühlketten und CRT 2Early Key Findings from the Medical Affairs Consortium Research 2
... 27 Due to rising patient responsibility for ... state laws requiring disclosure of information on hospital charges, ... estimates for healthcare services. Competitive hospitals also realize they ... accountability to key stakeholders, protect against compliance risks, focus ...
... , , ... 280,000 external defibrillators used worldwide in health care facilities, public places, or in the home ... Drug Administration warned today. , , , ... , , , ...
Cached Medicine Technology:Craneware Shares Patient Estimation Revenue Integrity Insights 2Craneware Shares Patient Estimation Revenue Integrity Insights 3Craneware Shares Patient Estimation Revenue Integrity Insights 4FDA Warns Users About Faulty Components in 14 External Defibrillator Models 2FDA Warns Users About Faulty Components in 14 External Defibrillator Models 3
Hatsis tying forceps, titanium, long thin tying platforms....
Gills Colibri forceps, very fine pointed tips....
Fine tying forceps, curved tips, wide handle....
Castroviejo tying forceps, tying platforms, straight, 0.3 mm teeth....
Medicine Products: