Navigation Links
Human Stem Cell Transplant Helps Brain-Impaired Mice
Date:6/4/2008

Restored damaged electrical pathway seen in MS patients who lose nerve signals

WEDNESDAY, June 4 (HealthDay News) -- Mice with a congenital brain disorder improved after receiving human neural stem cell transplants, a U.S. study finds.

The mice lacked myelin, a substance that plays a critical role in the transmission of electrical signals between nerve cells. When myelin is missing or damaged, electrical signals aren't properly transmitted. These "shiverer" mice typically die within months of birth.

Demyelination also occurs in people with multiple sclerosis.

Previous research has examined the use of cell transplantation for restoring absent or lost myelin to diseased nerve fibers. But, until now, no transplantation of human neural stem cells or of their derivatives (glial progenitor cells) had been successful in test animals.

In this new study, researchers from the University of Rochester Medical Center and a number of other universities (Cornell, UCLA and Baylor) created a new method for harvesting and purification of human fetal glial progenitor cells.

They also developed a new cell delivery strategy that uses multiple injection sites to encourage widespread and dense take-up of the transplanted cells through the central nervous system.

When the researchers used these new approaches, the transplanted cells took hold throughout the brain and spinal cord, and the mice showed robust, efficient and functional myelination. Some of the mice showed neurological improvement and a fraction of them were save by the procedure.

"The neurological recovery and survival of the mice receiving transplants was in sharp contrast to the fate of their untreated controls, which uniformly died by five months," researcher Dr. Steve Goldman, of the departments of neurology and neurosurgery at the University of Rochester Medical Center, said in a prepared statement.

"To our knowledge, the
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Public funding impacts progress of human embryonic stem cell research
2. Virginia Tech researchers find human virus in chimpanzees
3. How defects in 1 gene cause 3 distinct and devastating human diseases
4. New method identifies rat poison in humans
5. Best Practice Database Optimizes Human Resource Management
6. TU Delft robot Flame walks like a human
7. A potential route for human tumor gene therapy
8. Project HOPE to Send Humanitarian Assistance to China as Humanitarian Assistance to Myanmar Continues
9. New Therapy Kills Human Leukemia Cells in Mice
10. Human Pheromone Sciences Announces First Quarter Results
11. Researchers find first conclusive evidence of Alzheimers-like brain tangles in nonhuman primates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... On October 22, CBS will air ... diseases both fictional and real. The Charles E ... committed to advocacy and philanthropy in the battle against ... opportunity to impart truth and clarity about this misunderstood ... many misconceptions about Morgellons Disease (MD) and ...
(Date:10/22/2014)... Springfield, Va. (PRWEB) October 22, 2014 For ... way to make money; it’s an extension of her life’s ... her latest venture as the owner of FirstLight HomeCare, make ... , “It’s important to me that my work makes a ... always harbored an entrepreneurial spirit, so after much research, I ...
(Date:10/22/2014)... Shriners Hospitals for Children® and UK HealthCare have ... of Shriners Hospitals for Children - Lexington from 1900 ... of Kentucky Albert B. Chandler Hospital. The new facility ... operated by Shriners Hospitals for Children, and designed to ... families well into the future. , “The quality care ...
(Date:10/22/2014)... 22, 2014 With the Affordable Care Act ... by the American Institutes for Research (AIR) finds that three ... use health insurance, but 42 percent say they are not ... before signing up for coverage. , The AIR survey found ... percent able to calculate correctly how much they owe for ...
(Date:10/22/2014)... Healthcare professionals who are looking ... at home or on-the-go via laptops, tablets or ... new, premium Seminar-on-Demand CE courses. The new courses ... 2,000 hours of CE course offerings, allowing ... With such a diverse library, there’s something for ...
Breaking Medicine News(10 mins):Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 3Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 2Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 4Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2
... radiation used to reduce side effects is not as ... standard chemotherapy in the treatment of Hodgkin,s lymphoma patients ... study presented at the plenary session, November 1, 2010, ... for Radiation Oncology (ASTRO). , In addition, the trial ...
... Washington, October 25, 2010 The Life Sciences Discovery Fund ... Omeros Corporation (NASDAQ: OMER) to discover, develop, and commercialize ... With successful generation of proceeds through partnering and the ... of the grant would be establishment of a new ...
... 25 (HealthDay News) -- Patients who receive radiation before surgery ... experience a return of their cancer, a new Dutch study ... to the original tumor site and surrounding area -- is ... explained the researchers from Leiden University Medical Center in the ...
... pathway that, when blocked, significantly decreases the spread of ... at The University of Texas MD Anderson Children,s Cancer ... in mice decreased metastases in the lungs 15-fold. The ... Sunday in an oral presentation at the 42nd Congress ...
... woman is perfectly clear in expressing sexual interest or rejection, ... a new University of Iowa study shows. Overall, college-age ... in this case, represented through photos showed interest. ... be good looking, dressed more provocatively, and conveyed interest through ...
... public to report sick or dead wild animals could also ... that may pose a health risk to people. , The ... www.wher.org that enables anyone with an Internet connection ... has enhanced its mobile phone application "Outbreaks Near Me" to ...
Cached Medicine News:Health News:Newer, more intense chemotherapy with less radiation not more effective against Hodgkin's lymphoma 2Health News:Life Sciences Discovery Fund to support drug discovery, foster new R&D initiative 2Health News:Life Sciences Discovery Fund to support drug discovery, foster new R&D initiative 3Health News:Radiation Before Surgery May Prevent Return of Rectal Cancer 2Health News:Researchers find pathway that drives spread of pediatric bone cancer in preclinical studies 2Health News:UI study investigates variability in men's recall of sexual cues 2Health News:Wildlife health reporting tools may help prevent human illness 2Health News:Wildlife health reporting tools may help prevent human illness 3
(Date:10/22/2014)... , Oct. 22, 2014 Moms are ... health trackers for themselves and their kids, according to ... Report: Health & Fitness Go Mobile for Moms, the ... Series. BabyCenter, the number 1 pregnancy and parenting web ... that 55 percent of moms surveyed say they can,t ...
(Date:10/22/2014)...  With a vision to ensure safety and ... Pharmaceutical and Biotech manufacturer selects and implements the ... to protect their animal health brand.  ... Photo - http://photos.prnewswire.com/prnh/20141021/153439 ... by the Xyntek and Antares solution is an ...
(Date:10/22/2014)... 2014 Influenza will affect as many as 200,000 ... the United States as high as 49,000 people.  ... is from person to person in respiratory droplets of coughs ... of death, but kills much fewer people each year than ... human fluids including sweat, saliva, blood and other bodily fluids. ...
Breaking Medicine Technology:BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 2BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 3BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 4Xyntek and Antares Serialization Solution Protects Pets Too! 2WholeHealth Products is proud to be releasing its Influenza A and B combo test, on the heels of the announcing of its phase 2 completion of the Rapid Ebola Test 2
... Awarepoint Corporation announced today that CEO Jay Deady will ... Healthcare Innovation Summit on April 14, 10:30 a.m. – ... York. Joining Deady on the panel will be Harry Greenspun, ... Safavi, M.D., vice president and global lead of the Cisco ...
... Encision Inc. (Pink Sheets: ECIA ) ... intensive topics of discussion in recent publications, most notably ...  The potential complications from laparoscopic surgery are highlighted in ... recent California case.  The issue focuses on safer abdominal ...
Cached Medicine Technology:Awarepoint CEO Jay Deady to Serve as Panelist at IBF's Digital Healthcare Innovation Summit 2Awarepoint CEO Jay Deady to Serve as Panelist at IBF's Digital Healthcare Innovation Summit 3Stray Energy Burns Become a "Hot Topic" in Recent Publications 2Stray Energy Burns Become a "Hot Topic" in Recent Publications 3
... optimize the accuracy and precision of Finnpipettes. ... widely recognized by customers throughout the world. ... the years and now covers a full ... filter tips, certified pure tips, stepper tips ...
... Finntips have been designed to optimize the ... of our tip products is widely recognized ... range has been extended over the years ... standard and special tips including filter tips, ...
... Eppendorf Style Low Binding, Graduated Pipet Tips ... fit Eppendorf Style Pipettors.Reduces DNA and protein ... packaged completely by automation. RNAse & DNAse ... 96 tips/rack and 10 racks/cs. AVR100 is ...
... Packed conveniently in plastic-wrapped racks of 96 ... useno need to autoclave. Sterilized Diamond Tips ... sterilization and are delivered with a certificate ... Sterilized Diamond Tips are certified free of ...
Medicine Products: