Navigation Links
Human Extracellular Matrix Significantly Improves Device Biocompatibility
Date:5/28/2010

lar market and have had a major impact on patient care," said Dr. Gail Naughton, CEO and Chairman of the Board at Histogen. "Problems such as fibrous capsule formation, poor tissue ingrowth, and neointimal hyperplasia resulting from suboptimal biocompatibility must be addressed to offer improved patient benefits. We are encouraged by the results with our embryonic-like matrix, which demonstrate its potential for reducing the foreign body reaction, as well as improving and prolonging the life and function of implantable devices."

Testing, which was performed as part of a partnership with the National Research Council's Advanced Materials Division, involved coating of several commonly utilized device materials, including nylon, polypropylene (PPE), and polyethylene terephthalate (PET) nonwoven scaffolds with hECM using several common coating methods. The hECM-coated and uncoated scaffolds were then surgically implanted in the subcutaneous space of SCID mice and histological samples of excised implants were assessed for inflammatory response, cellular infiltration, foreign body giant cells and capsule formation.

"Coating polymers with a naturally-produced, all-human ECM masks the foreign device material and offers a physiological surface which supports healthy tissue infiltration and interaction," said Dr. Michael Zimber, Director of Applied Research at Histogen. "The hECM-coated polymers promoted a two-fold increase in normal cell proliferation as compared to uncoated polymers, as well as causing a significant reduction in the host inflammatory and fibrotic response to surgically implanted polymers."

"Coating Polymers with a Human Extracellular Matrix Significantly Improves Implant Biocompatibility" will be presented by Dr. Zimber at the ASAIO Annual Conference, taking place May 27-29, 2010 in Baltimore.

About Histogen
Histogen, launched in 2007, seeks to redefine regenerative med
'/>"/>

Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Study finds law-like patterns in human preference behavior
2. Genentech uses Complete Genomics human genome sequencing service to compare tumor and normal genome in patient with non-small cell lung cancer; results published in Nature
3. Discovery of Stem Cell Illuminates Human Brain Evolution, Points To Therapies
4. The Human Spirit is Indomitable
5. Scientists Map Genetic Codes of Human Microbes
6. Oncolytic viruses mediating anti-tumor immunity in human cancer patients
7. BHM Healthcare Congratulates PORT Human Services: First to Receive CABHA Status
8. The cost of medicalizing human conditions
9. It was brawn over beauty in human mating competition
10. Human Touch Brand Ambassador and PGA Pro Tim Clark Wins First PGA TOUR Victory at PLAYERS Championship
11. McGill-UBC project creates mouse grimace scale to help identify pain in humans and animals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... July 31, 2015 , ... There’s no better way to ... it comes time to cook the next meal, making July the most appropriate to ... best grilling tips and recipes. , Make the next cookout different than the ones ...
(Date:7/31/2015)... Rolling Meadows, IL (PRWEB) , ... July 31, ... ... great ways to communicate. Rally Insurance Group, Inc. has re-branded their social media ... provides a personal way for consumers to communicate, find information, share insights ...
(Date:7/31/2015)... Washington, PA (PRWEB) , ... July 31, 2015 , ... ... specialties, is excited to launch three new Board Exam Courses. , The additions ... Smartest Doc Board Exam Prep from MDLinx makes preparing for the exam easy and ...
(Date:7/31/2015)... Los Angeles, CA (PRWEB) , ... July 31, 2015 , ... According to the ... the third floor of the Pasadena courthouse was contained and extinguished by the city’s fire ... one was in the building at the time of the fire, and it was a ...
(Date:7/31/2015)... ... 2015 , ... Well-known for its unique pastries and delicious confections, Pastry Palace, ... designs, making life just a little bit sweeter for newlyweds. A family-owned business, the ... orders one. , The bakery provides a full line of custom wedding cakes. Brides ...
Breaking Medicine News(10 mins):Health News:King Kullen Honors National Hot Dog and Blueberry Month 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 3Health News:Rally Insurance Group, Inc. Connects to Customers Through Re-branded Social Media Profiles 2Health News:MDLinx Offers Three New Board Exam Prep Courses - Gastroenterology, Pulmonology and Allergy/Immunology 2Health News:MDLinx Offers Three New Board Exam Prep Courses - Gastroenterology, Pulmonology and Allergy/Immunology 3Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3Health News:Pastry Palace of Las Vegas Announces It Is Now Offering Custom Wedding Cakes in Las Vegas 2
... small reduction in LDL cholesterol can contribute to far reaching ... to a US study, scientists have said that even a ... is amply found in the dairy products, meat and hydrogenated ... nearly 50%. ,The study on this subject was ...
... claim that more people could be at risk of ... previously thought after new evidence emerged that the condition ... to the scientists from Edinburgh a long incubation period ... blood transfusions and surgical instruments, can become a significant ...
... physicians who provide free care to the poor has ... becoming huge problem for America’s quickly growing number of ... conducted by the Center for Studying Health System Change, ... care in the mid-1990s, compared with about two-thirds now. ...
... patients who participated in a UC Davis study of ... blood pressure. // ,Conducted by UC Davis ... trial to assess the effect of grape seed extract ... factors that increase the risk for heart disease, including ...
... are well aware of Kawasaki as a motorcycle rather than ... doctors informed that his 9 year old daughter, Utkarsha was ... so as it is prevalent among Korean and Japanese children. ... that Kawasaki was a disease,' remarked Dinesh Ghai. ...
... world tuberculosis day. It was thought decades ago that the ... still remains a major // threat and its toll still ... rising at almost 1% every year despite the efforts taken ... globally in 2004 and infected nearly 9 million, according to ...
Cached Medicine News:Health News:Mad Cow Disease – Worst Is Yet To com 2Health News:Fewer Doctors Treating For Free 2Health News:High Blood Pressure Can Be Treated With Grape Seed Extract 2Health News:Low Awareness Of Kawasaki Disease In Capital: Parents Form Support Group 2Health News:Tuberculosis Is Still A Major Health Threat In Africa 2
(Date:7/31/2015)... India , July 31, 2015 ... CRM solutions for video, data and cloud computing ... with a leading pharma giant for Internet of ... different IoT applications offered on subscription model. ... Pharma giant is striving for business innovations ...
(Date:7/30/2015)... Calif. , July 30, 2015 IRIDEX ... will release its second quarter 2015 financial results after ...   In conjunction with the release, the Company will ... 5:00 p.m. Eastern Time on Thursday, ... the quarter and other business developments. Interested ...
(Date:7/30/2015)... you a special edition of #MedicareMonday on Medicare,s 50 th anniversary. As Medicare ... and continue highlighting the success of the prescription drug benefit, commonly referred to as ... latest infographics and videos here: http://onphr.ma/1INp9qQ ... ... ...
Breaking Medicine Technology:Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2IRIDEX Announces Second Quarter 2015 Conference Call and Release Date 2Happy 50th Anniversary Medicare! 2Happy 50th Anniversary Medicare! 3
... Takeda Global Research & Development Center, Inc., ... (FDA) has assigned a Prescription Drug User Fee Act ... review of its investigational type 2 diabetes therapy alogliptin, ... with pioglitazone in a single tablet.   ...
... its third annual Human Milk (breast milk) Collection Campaign in ... As part of the campaign, Medela will donate a total ... units across the country. "We want to do ... of human milk feeding -- to help protect premature babies ...
Cached Medicine Technology:Takeda Announces PDUFA Action Date for Investigational Type 2 Diabetes Therapies Alogliptin and the Fixed-Dose Combination Alogliptin/Pioglitazone 2Takeda Announces PDUFA Action Date for Investigational Type 2 Diabetes Therapies Alogliptin and the Fixed-Dose Combination Alogliptin/Pioglitazone 3Medela Announces Virtual Breast Milk Collection Campaign in Honor of Prematurity Awareness Month 2
300XL System, English (U.K. cord), 100-240 VAC....
Micro-mini fiber optic light....
Micro-mini fiber optic light....
The MC-3 allows for simultaneous use of two lamps, with an additional built-in spare....
Medicine Products: