Navigation Links
Human Cells Used to Make Replacement Anal Sphincters in Mice
Date:8/10/2011

WEDNESDAY, Aug. 10 (HealthDay News) -- The first working, replacement anal sphincters have been built in a laboratory and tested on mice.

Now scientists hope the research will benefit humans with fecal and urinary incontinence, because current methods used to repair internal anal sphincters, such as skeletal muscle grafts, silicone injections or mechanical implants, have had only limited success.

"In essence, we have built a replacement sphincter that we hope can one day benefit human patients. This is the first bioengineered sphincter made with both muscle and nerve cells, making it 'pre-wired' for placement in the body," senior author Khalil N. Bitar, a professor of regenerative medicine at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine, said in a Wake Forest news release.

Scientists were able to make the bioengineered anal sphincters in about six weeks using human muscle and nerve cells. They found the sphincters were able to generate blood supply and work properly in mice.

The investigators hope their research will lead to a more effective treatment for humans because there is a high rate of weakened internal anal sphincters in older adults. Women who had episiotomies during childbirth can also be affected by this condition.

"Many individuals find themselves withdrawing from their social lives and attempting to hide the problem from their families, friends, and even their doctors," said Bitar. "Many people suffer without help."

Repeated laboratory tests of the engineered sphincters showed they functioned normally, relaxing and contracting, in the mice. The sphincters were also re-tested after a period of 25 days and compared to the mice's original sphincters. The researchers found the man-made sphincters continued to work like natural ones.

The mice chosen for the experiment had suppressed immune systems to reduce the risk of rejection of the new sphincters, the s
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Education -- a key determinant of population growth and human well-being
2. Human Brains Wired to Empathize, Study Finds
3. Dolphins Superior Ability to Heal May Help Humans
4. Ancient Footprints Reveal Earliest Signs of Human-Like Gait
5. INFORMS: CARE positions disaster relief with promising discipline of humanitarian logistics
6. INFORMS journal announces special issue on using logistics, analytics in humanitarian relief
7. Dolphins remarkable recovery from injury offers important insights for human healing
8. Genetic map of African-Americans to aid study of diseases, human evolution
9. BIDMC to co-lead NIH consortium for AIDS vaccine research in nonhuman primates
10. IBD, LCPD health research in Westie dogs may hold answers to similar human diseases
11. Human Stem Cells Used to Fix Damaged Mouse Heart
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Human Cells Used to Make Replacement Anal Sphincters in Mice 
(Date:7/28/2014)... 2014 Community Health Center of Snohomish ... and pharmacy services, has released an article designed to ... management . Founded in 1983, the health center has ... the county that face barriers to obtaining high quality ... appointment at the CHC, click here: http://www.chcsno.org/locations.ashx?p=1099 ...
(Date:7/28/2014)... Alta Resources , a global provider ... 500 brands, announced today that it plans to fill ... California, Florida and the Philippines. More than 1,200 of ... campus, and the company announced that approximately 700 positions ... several health-insurance clients, which have seasonal ramp-ups that require ...
(Date:7/28/2014)... Labors.at, Austria’s largest and most progressive ... Cloud™ to fuel its growth initiatives. The organization, ... patients daily and performs up to 70,000 diagnostic ... doubling its volume within the next year. ... square meter facility pushed our team to re-evaluate ...
(Date:7/28/2014)... 2014 H2T Elite Dryland Training will be ... 573 Alness Street in Toronto, H2T is focused ... H2T is a state of the art facility that specializes ... are many gyms out there for people 18 and older ... H2T will be home to many elite athletes that will ...
(Date:7/28/2014)... following a healthy lifestyle may lower childhood cancer survivors, ... in CANCER , a peer-reviewed journal of the ... cancer and adults who had cancer when they were ... influence their long-term health. , Adults who had ... risk for the metabolic syndrome, a group of risk ...
Breaking Medicine News(10 mins):Health News:Community Health Center of Snohomish Releases Article Focusing on Educating the Chronically Ill About Chronic Disease Management 2Health News:Community Health Center of Snohomish Releases Article Focusing on Educating the Chronically Ill About Chronic Disease Management 3Health News:Alta Resources To Fill Approximately 1,200 Positions In Fort Myers 2Health News:Alta Resources To Fill Approximately 1,200 Positions In Fort Myers 3Health News:Alta Resources To Fill Approximately 1,200 Positions In Fort Myers 4Health News:Austrian Laboratory Leader, Labors.at, Fuels Growth with the hc1® Healthcare Relationship Cloud™ 2Health News:FS Local Community Member H2T Elite Dryland Training Is Set to Open Its Doors 2Health News:Lifestyle choices may affect the long-term heart health of childhood cancer survivors 2
... , TONBRIDGE, England, Sept. ... innovation of the past 150 years, by leading figures in the ... the electric light bulb and penicillin in a star-studded competition organised ... The final four inventions went head-to-head in a live debate, with ...
... , , MIDDLETOWN, Conn., Sept. ... Blue Cross and Blue Shield Foundation grant to the national ... $37,500 to fund the "Family Link" program here in Connecticut. ... community-based network that connects parents of children with diabetes with ...
... , , ... (AFA) today applauded Senate Finance Committee Chairman Max Baucus (D-MT) ... including cognitive impairment screening for Medicare beneficiaries in Baucus, healthcare ... , , AFA had pressed for cognitive ...
... , , , MINNEAPOLIS, Sept. ... health by helping yogurt lovers regulate digestive health without compromising calorie ... Available in three delicious flavors -- Honey Vanilla, Strawberry Banana and ... Light is an easy way to help keep your digestive health ...
... , , , NEW YORK, Sept 17 ... today announced that it will host The Runyon 5K , ... on Sunday, November 15th 2009. Proceeds from the event, the first of ... scientists carrying out innovative research for all types of cancer. , ...
... Sept. 17, 2009 The Wellcome Trust and Merck ... MSD Wellcome Trust Hilleman Laboratories ( www.hillemanlaboratories.in ), the ... with a not-for-profit mission to focus on developing affordable ... The joint venture marks the first ...
Cached Medicine News:Health News:Contraceptive Pill Named the Greatest Pharmacy Invention of the Last 150 Years in Chemist+Druggist Competition 2Health News:Anthem Blue Cross and Blue Shield Foundation Grant Supporting American Diabetes Association's 'Family Link' Program In Connecticut 2Health News:Anthem Blue Cross and Blue Shield Foundation Grant Supporting American Diabetes Association's 'Family Link' Program In Connecticut 3Health News:Alzheimer's Foundation of America Applauds Inclusion of Cognitive Screening for Medicare Beneficiaries in Senate Finance Committee Health Reform Proposal 2Health News:Alzheimer's Foundation of America Applauds Inclusion of Cognitive Screening for Medicare Beneficiaries in Senate Finance Committee Health Reform Proposal 3Health News:Photos: New Yoplait(R) YoPlus(TM) Light... A Delicious Way to Regulate Digestive Health With Fewer Calories 2Health News:Photos: New Yoplait(R) YoPlus(TM) Light... A Delicious Way to Regulate Digestive Health With Fewer Calories 3Health News:Damon Runyon 5K Run/Walk at Yankee Stadium to Benefit Cancer Research 2Health News:Damon Runyon 5K Run/Walk at Yankee Stadium to Benefit Cancer Research 3Health News:Damon Runyon 5K Run/Walk at Yankee Stadium to Benefit Cancer Research 4Health News:Wellcome Trust and Merck launch joint venture to develop affordable vaccines 2Health News:Wellcome Trust and Merck launch joint venture to develop affordable vaccines 3Health News:Wellcome Trust and Merck launch joint venture to develop affordable vaccines 4
(Date:7/28/2014)... , Germany und ... , Ziel ... das auf Basis genomischer Daten aus Plasmaproben zur ... nicht-kleinzelligem Lungenkrebs eingesetzt werden kann  Neuer ... therascreen   EGFR Kit und soll auf Rotor-Gene Q, ...
(Date:7/25/2014)... N.C. , July 25, 2014  Corporate libraries ... including understanding new advancements in technology and how to ... this, libraries in the pharmaceutical and medical device industries ... of the information and services they provide. ... Practices, LLC there are many forces of change that ...
(Date:7/25/2014)... /PRNewswire-iReach/ -- ScriptPro, of Mission, Kansas ... Lake, Wisconsin , announce that they will ... agreement allowing ScriptPro to bring TCGRx adherence packaging ... United States . ScriptPro is a leading ... to retail and ambulatory pharmacies. TCGRx distributes and ...
Breaking Medicine Technology:QIAGEN und AstraZeneca entwickeln Begleittest auf Basis von Flüssigbiopsien zur erweiterten Bestimmung von EGFR-Mutationen bei Lungenkrebspatienten 2QIAGEN und AstraZeneca entwickeln Begleittest auf Basis von Flüssigbiopsien zur erweiterten Bestimmung von EGFR-Mutationen bei Lungenkrebspatienten 3QIAGEN und AstraZeneca entwickeln Begleittest auf Basis von Flüssigbiopsien zur erweiterten Bestimmung von EGFR-Mutationen bei Lungenkrebspatienten 4QIAGEN und AstraZeneca entwickeln Begleittest auf Basis von Flüssigbiopsien zur erweiterten Bestimmung von EGFR-Mutationen bei Lungenkrebspatienten 5QIAGEN und AstraZeneca entwickeln Begleittest auf Basis von Flüssigbiopsien zur erweiterten Bestimmung von EGFR-Mutationen bei Lungenkrebspatienten 6QIAGEN und AstraZeneca entwickeln Begleittest auf Basis von Flüssigbiopsien zur erweiterten Bestimmung von EGFR-Mutationen bei Lungenkrebspatienten 7Forces of Change Reshaping Corporate Libraries & Information Services 2ScriptPro and TCGRx Integrate Pharmacy Automation Technologies 2ScriptPro and TCGRx Integrate Pharmacy Automation Technologies 3
... in bone mineral density at the,lumbar spine and ... salmeterol inhalation powder) and salmeterol, - Study ... in patients,with COPD, PHILADELPHIA, Oct. 29 ... three-year study of patients with,Chronic Obstructive Pulmonary Disease ...
... Cryoablation ... Treatment Technology, PLEASANTON, ... (ACOSOG) which just initiated a National Cancer,Institute (NCI) funded clinical ... Therapy in the Treatment of Invasive Breast,Carcinoma," has selected the ...
Cached Medicine Technology:Study Found That Long Term Use of Advair Diskus(R) 250/50 Did Not Adversely Affect Bone Loss in Patients with COPD 2Study Found That Long Term Use of Advair Diskus(R) 250/50 Did Not Adversely Affect Bone Loss in Patients with COPD 3NCI Funded Clinical Trial to Study Treatment of Breast Cancer Using Cryoablation 2NCI Funded Clinical Trial to Study Treatment of Breast Cancer Using Cryoablation 3
The Advia 60 is designed to deliver powerful performance in a small package....
... three-dimensional VCS technology, providing ... efficiency in white cell ... With its reputation for ... is an affordable solution ...
Creatinine Test Kit (enzymatic), Wavelength: 340 nm. Linear range: up to 20 mg/dL....
For the quantitative determination of Creatine Kinase in serum....
Medicine Products: