Both the UK and Canada have experienced huge falls in diabetes-related mortality since the mid-1990s, with the result that the gap in mortality risk between those with and without diabetes has narrowed substantially. The findings are in new research published in Diabetologia, the Journal of the European Association for the Study of Diabetes (EASD), and written by Dr Marcus Lind, Sahlgrenska Academy, University of Gothenburg, Sweden and colleagues.
A previous review of studied investigated diabetes mortality suggested that having diabetes increased a person's mortality risk by 80% compared with the general population.
However, many studies in the review were from before 2000, and some recent studies have suggested diabetes might increase mortality by less than this.
Thus in this new study, the authors estimated the current mortality rate ratio in patients with versus without diabetes and whether it has changed over time.
The UK and Canada were selected for analysis because the authors in both nations and Sweden are part of an ongoing collaboration, and this is a study objective that cannot be examined in many countries, since there are limited numbers of databases with long follow-up which are also population-based with mortality data on individuals both with and without diabetes. Both Canada and the UK hold such data.
The population-based databases from the province of Ontario, Canada, and The Health Improvement Network (THIN) database from the UK, from years 1996 to 2009 were used to calculate mortality rates in persons with and without diabetes.
The excess risk of mortality estimated during 2009 was 51% in Ontario and 65% in THIN for diabetic patients on a group level, compared to 90% and 114%, respectively, in the year 1996. The excess risk of mortality for diabetic patients declined to a similar extent for men and women over the study period, and no significant differences between sexes were observed in 2009.
|Contact: Marcus Lind|
University of Gothenburg