Navigation Links
How the brain makes memories: Rhythmically!
Date:10/3/2011

The brain learns through changes in the strength of its synapses -- the connections between neurons -- in response to stimuli.

Now, in a discovery that challenges conventional wisdom on the brain mechanisms of learning, UCLA neuro-physicists have found there is an optimal brain "rhythm," or frequency, for changing synaptic strength. And further, like stations on a radio dial, each synapse is tuned to a different optimal frequency for learning.

The findings, which provide a grand-unified theory of the mechanisms that underlie learning in the brain, may lead to possible new therapies for treating learning disabilities.

The study appears in the current issue of the journal Frontiers in Computational Neuroscience.

"Many people have learning and memory disorders, and beyond that group, most of us are not Einstein or Mozart," said Mayank R. Mehta, the paper's senior author and an associate professor in UCLA's departments of neurology, neurobiology, physics and astronomy. "Our work suggests that some problems with learning and memory are caused by synapses not being tuned to the right frequency."

A change in the strength of a synapse in response to stimuli -- known as synaptic plasticity -- is induced through so-called "spike trains," series of neural signals that occur with varying frequency and timing. Previous experiments demonstrated that stimulating neurons at a very high frequency (e.g., 100 spikes per second) strengthened the connecting synapse, while low-frequency stimulation (e.g., one spike per second) reduced synaptic strength.

These earlier experiments used hundreds of consecutive spikes in the very high-frequency range to induce plasticity. Yet when the brain is activated during real-life behavioral tasks, neurons fire only about 10 consecutive spikes, not several hundred. And they do so at a much lower frequency -- typically in the 50 spikes-per-second range.

In other words
'/>"/>

Contact: Mark Wheeler
mwheeler@mednet.ucla.edu
310-794-2265
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Yawning May Help the Brain Chill Out
2. Brain Continues to Develop Beyond Adolescence
3. Stanford brain imaging study shows physiological basis of dyslexia
4. Louisiana State University Health Sciences Center research discovers key to survival of brain cells
5. How normal cells become brain cancers
6. New modeling of brains circuitry may bring better understanding of Parkinsons disease
7. Could Too Little Vitamin B-12 Shrink the Aging Brain?
8. Could targeting a virus treat a common pediatric brain tumor?
9. Some brain wiring continues to develop well into our 20s: U of A study
10. The disinhibited brain
11. Buyer beware: Advertising may seduce your brain, UCLA researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... injuries increase in the summer as people gather around fire ... most vulnerable to these seasonal fire hazards: children. "Young ... by putting their hands on the side of cooking grills," ... Loyola University Medical Center in Maywood, Ill., said in a ... play with fire, you get burned, is true -- ...
(Date:7/12/2014)... Sean Francis, owner of the Kawartha Lakes Fit ... his clients. He’s also known for his support of local non-profits ... to combine the two and is excited to announce that his ... and Girls Club. , The funds are the result of Francis’ ... Francis sent out emails and asked his clients to put out ...
(Date:7/12/2014)... PA (PRWEB) July 12, 2014 Using ... so one of two inventors from Ashland, Va., decided ... do this. "This inspired us to conceive of our ... of the patent-pending KIDNEY KOVER, which provides an inconspicuous ... It avoids embarrassment, as well as promotes comfort and ...
(Date:7/12/2014)... With prom shopping reaching its final days, ... ready to showcase its new and trendy apparels. Recently, ... dresses in its online shop. Additionally, it is now ... elegant gowns. According to the company’s sales manager, the ... 2014. , He says, “Now, worldwide clients can ...
(Date:7/12/2014)... Wright & Schulte LLC has filed a DePuy ... of Johnson & Johnson, on behalf of an Ohio man ... metal-on-metal DePuy Pinnacle hip replacement and had to undergo revision ... The DePuy hip lawsuit was filed July 7, 2014, in ... 3:14-cv-2427) where DePuy Pinnacle Hip lawsuit litigation is underway ...
Breaking Medicine News(10 mins):Health News:Burn Injuries More Common in Summer 2Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 2Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 3Health News:VogueQueen.com Updates Its Summer Collection With New And Trendy Evening Dresses 2Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 2Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 3Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 4Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 5
... transparency for quality improvement.CHICAGO, April 6 ... www.siemens.com/healthcare ) will ... with Soarian(R) Quality Measures, enabled by the REMIND(TM) Platform, ... Society (HIMSS) 2009 Annual Conference and Exhibition in Chicago ...
... -- Harris Corporation (NYSE: HRS ) ... www.ctisus.com ) to deliver intuitive navigation to ... allied healthcare professionals who access the site every day ... and is maintained by The Advanced Medical Imaging Laboratory, ...
... (HIMSS,09, Booth #3974) -- Harris Corporation (NYSE: ... $14 million contract by Evolvent Technologies, Inc., to develop ... System,s global Healthcare Artifact and Image Management Solution (HAIMS). ... potential for four one-year incentive options. The announcement ...
... invites customers to just ,have fun, and use social ... 6 Baxa Corporation, a leading developer of technology ... medications, has joined the social media craze by hosting ... Group. More and more healthcare facilities, medical device ...
... ATLANTA, April 6 CryoLife, Inc., (NYSE: ... and tissue processing company, today announced it has ... of Defense (DoD) Appropriations Bill to continue further ... studies of CryoLife,s BioFoam(R) Surgical Matrix, a protein ...
... small study hint at cancer-preventing ability, researcher says , , MONDAY, ... of broccoli sprouts appeared to reduce the risk of stomach ... Gastric cancer thus joins a long list of malignancies for ... diet that contains broccoli -- including cancer of the esophagus, ...
Cached Medicine News:Health News:Siemens Enhances Knowledge-Driven Solutions to Support Provider Quality of Care Initiatives 2Health News:Siemens Enhances Knowledge-Driven Solutions to Support Provider Quality of Care Initiatives 3Health News:Harris Corporation Redesigning Popular Radiology Web Site to Enhance Content Management and Accessibility 2Health News:Harris Corporation Awarded $14 Million Contract to Develop Multi-Hospital Military Health System Network with Image-Sharing Capabilities 2Health News:Baxa Corporation Gets Social With Facebook and LinkedIn 2Health News:Baxa Corporation Gets Social With Facebook and LinkedIn 3Health News:Department of Defense Awards CryoLife $1.7 million to Develop BioFoam Hemostatic Technology 2Health News:Department of Defense Awards CryoLife $1.7 million to Develop BioFoam Hemostatic Technology 3Health News:Broccoli May Ward Off Serious Stomach Ailments 2Health News:Broccoli May Ward Off Serious Stomach Ailments 3
(Date:7/11/2014)... According to a new market ... (Endoscopes, Endoscopic Operative Devices, and Visualization Systems) - Global ... the global endoscopy devices market was valued at USD ... at a CAGR of 6.8% from 2013 to 2019, ... in 2019. Browse the full Endoscopy Devices Market ...
(Date:7/11/2014)... Neurelis, Inc. ("Neurelis") today announced an agreement ... held by Biotie to purchase Neurelis, clearing the way ... diazepam) for pediatric and adult epilepsy patients who experience ... Biotie has advanced the development program for NRL-1 and ... work required for NDA submission to the FDA.  Given ...
(Date:7/10/2014)... 2014  Breg, Inc., a premier provider of ... FreeRunner™ knee brace with new innovations to help ... return to active lifestyles.  FreeRunner,s patent-pending design acts ... support when patients need it most, and the ... Patellofemoral issues are the most common cause ...
Breaking Medicine Technology:Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2
... MADISON, Wis., Aug. 8, 2011 Symphony Corporation, ... the acquisition of JGI, a New Jersey-based Human ... significant presence in the healthcare industry nationally.  Symphony,s ... its offerings to provide the highest level of ...
... DIEGO, Aug. 8, 2011 HUYA Bioscience International, a ... strategic partnership with the Shanghai Jiao Tong University School ... assist King,s Lab in accelerating the development of their ... provides HUYA with access to and first review of ...
Cached Medicine Technology:Symphony Corporation Acquires JGI to Provide End-to-End Services for Healthcare IT 2HUYA Bioscience International and Shanghai Jiao Tong University King's Lab Form Alliance 2HUYA Bioscience International and Shanghai Jiao Tong University King's Lab Form Alliance 3
... display of corneal layers: endothelium, ... epithelial layers. Accurate analysis of ... keratocytes, nerve fibres, basal & ... surgery and pathology: optical pachymetry, ...
The Ahmed Glaucoma Valve has been successfully demonstrated to work in all types of glaucoma cases, particularly neovascular, congenital and uvietic glaucoma....
Ahmed Glaucoma Valve with Pars Plana Clip....
Ahmed Glaucoma Valve Flexible Plate ....
Medicine Products: