Navigation Links
How the brain loses and regains consciousness
Date:3/4/2013

ons also prevent different parts of the cortex from coordinating with each other. In last year's study, the researchers found that during anesthesia, neurons within small, localized brain regions are active for a few hundred milliseconds, then shut off again for a few hundred milliseconds. This flickering of activity, which creates the slow oscillation pattern, prevents brain regions from communicating normally.

Better anesthesia monitoring

When the researchers began to slowly decrease the dose of propofol, to bring the subjects out of anesthesia, they saw a reversal of the brain activity patterns that appeared when the subjects lost consciousness. A few minutes before regaining consciousness, the alpha oscillations flipped so that they were at their peak when the low-frequency waves were at their lowest point.

"That is the signature that would allow someone to determine if a patient is coming out of anesthesia too early, with this drug," Purdon says.

Cases in which patients regain consciousness during surgery are alarming but very rare, with one or two occurrences in 10,000 operations, Brown says.

"It's not something that we're fighting with every day, but when it does happen, it creates this visceral fear, understandably, in the public. And anesthesiologists don't have a way of responding because we really don't know when you're unconscious," he says. "This is now a solved problem."

Purdon and Brown are now starting a training program for anesthesiologists and residents at MGH to train them to interpret the information necessary to measure depth of anesthesia. That information is available through the EEG monitors that are now used during most operations, Purdon says. Because propofol is the most widely used anesthesia drug, the new findings should prove valuable for most operations.

In follow-up studies, the researchers are now studying the brain activity patterns produced by other anesthesia d
'/>"/>

Contact: Sarah McDonnell
s_mcd@mit.edu
617-827-7637
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Very low risk of infections in advanced brain procedures
2. New chemical probe provides tool to investigate role of malignant brain tumor domains
3. Study identifies growth factor essential to the most common malignant pediatric brain tumor
4. Research: Brain cant cope with making a left-hand turn and talking on hands-free cell phone
5. UGA researchers identify brain pathway triggering impulsive eating
6. Brain-to-brain interface allows transmission of tactile and motor information between rats
7. Traumatic Brain Injury (TBI) Legal Resource For People Seeking Legal Options Unveiled at LawsuitLegal.com
8. Einstein receives $3 million to study impact of soccer heading on the brain
9. Network analysis of the brain may explain features of autism
10. Brain Connections Differ in Children With Autism
11. Scientists Pinpoint How Deep Brain Stimulation Eases OCD
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... AMERICAN FORK, Utah (PRWEB) August 21, 2014 ... patient engagement requirement of the Affordable Care Act according to ... participated in the report by responding to a request from ... used to engage patients may lead providers to violate privacy ... patient engagement is possible, but many hospitals and clinics are ...
(Date:8/21/2014)... August 21, 2014 If chocolate is good ... will soon be very happy and healthy. Tracie is the ... Break ” contest. She and three of her coworkers will ... luxuriate at the world-famous Chocolate Spa® at The Hotel Hershey® ... third year working in the ambulatory surgery center at Connecticut ...
(Date:8/21/2014)... Consilium Staffing, Your Partner in Locum Tenens, ... in response to the President’s landmark VA hospital reform ... the Department of Veterans Affairs to hire more doctors. ... one hundred fifty medical centers nationwide, and has been ... awaiting treatment, including vets from the Vietnam War, Iraq, ...
(Date:8/21/2014)... San Diego, CA (PRWEB) August 21, 2014 ... website daily regarding all the latest information from the ... Solution . , The US FDA announced on August ... Peritoneal Dialysis Solution with 2.5% Dextrose 5000mL (Ambu-Flex II), ... to the presence of particulate matter. , The ...
(Date:8/21/2014)... Chicago, IL (PRWEB) August 21, 2014 ... its 33rd annual Inc. 500|5000, an exclusive ranking of ... most comprehensive look at the most important segment of ... Timberland, Dell, Domino’s Pizza, LinkedIn, Zillow, and many other ... Inc. 500|5000. , “Centurion is proud to have been ...
Breaking Medicine News(10 mins):Health News:Report: Only 20 Percent of Healthcare Providers Meet ACA Requirement 2Health News:Connecticut Nurse Wins a Sweet Prize from California Casualty 2Health News:Consilium Staffing Providing Locum Tenens in Response to VA Hospital Reform Legislation 2Health News:Dianeal Low Calcium (2.5mEq/L) Peritoneal Dialysis Solution with 2.5% Dextrose 5000mL (Ambu-Flex II) Recalled: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Centurion Service Group Named to Inc. Magazine's List of the Nation's Fastest-Growing Private Companies 2Health News:Centurion Service Group Named to Inc. Magazine's List of the Nation's Fastest-Growing Private Companies 3Health News:Centurion Service Group Named to Inc. Magazine's List of the Nation's Fastest-Growing Private Companies 4
... Now an Arizona cosmetic surgeon performs a unique procedure to harvest fat ... help women obtain shapely bodies. , ... Phoenix, AZ (PRWEB) November 6, ... to create a body you,ll love? , , ,Dr. Edgardo Zavala, a ...
... in Malibu, recently celebrated its fourth anniversary with a slew of ... current and past residents. , ... (PRWEB) November 6, ... in Malibu, recently celebrated its fourth anniversary with a slew of ...
... at least some comfort in a recent, first-of-its-kind study that ... significantly lower risk of breast cancer. Christopher I. Li, M.D., ... these findings in the November issue of Cancer Epidemiology, ... who had a history of migraines had a 30 percent ...
... age and race are among the factors that can ... after carotid-artery surgery, a UT Southwestern physician involved in ... identified 11 readily available, clinical risk factors that can ... the risks and benefits of carotid surgery for an ...
... The Global AIDS Alliance,today welcomed the election of ... "We look forward to working with President-elect Obama as ... over 5,000 people and,infects another 7,500 every day," said ... "As Colin Powell, Robert Rubin and others have recently ...
... million, Earnings per Diluted, Share of $0.32 and Contract Value of $230.6 million; ... ... 5 The Advisory Board Company,(Nasdaq: ABCO ) today announced financial results ... the quarter increased 7%,to $57.6 million, from $54.0 million in the second quarter ...
Cached Medicine News:Health News:Unsightly Fat Beautifies Body 2Health News:Unsightly Fat Beautifies Body 3Health News:Malibu Alcohol and Drug Rehab Center Celebrates Fourth Anniversary 2Health News:Migraines associated with lower risk of breast cancer 2Health News:Age, race are among factors that influence carotid-surgery success 2Health News:Global AIDS Alliance Welcomes Election of Barack Obama 2Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 2Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 3Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 4Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 5Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 6Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 7Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 8Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 9Health News:The Advisory Board Company Reports Fiscal Year 2009 Second Quarter Results 10
(Date:8/20/2014)... , Aug. 20, 2014 PTC Therapeutics, Inc. (NASDAQ: ... at two upcoming investor conferences: - FBR 1 ... in Boston on Wednesday, September 3 ... at The Mandarin Oriental Boston on Thursday, September 4 th ... company update at the Bank of America Merrill Lynch Global ...
(Date:8/20/2014)... Aug. 20, 2014 Torrance Memorial Medical ... advanced, ventilator technology from Covidien to provide a ... patients. The acute care ventilator is ... to conventional mechanical ventilation, and help clinicians move ... Patients on mechanical ventilation are often sedated to ...
(Date:8/20/2014)... 2014 Transparency Market ... Acid (MCA) Market for Cellulosics, Agrochemicals, Surfactants, Thioglycolic Acid ... Share, Growth, Trends and Forecast 2014 - 2020". The ... million in 2013 and is anticipated to reach USD ... 3.6% during the forecast period from 2014 to 2020. ...
Breaking Medicine Technology:PTC Therapeutics to Participate at Upcoming Investor Conferences 2Torrance Memorial Medical Center Acquires Advanced Ventilator Technology to Enhance Patient Care 2Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 2Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 3Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 4
... 6 Dendreon Corporation (Nasdaq:,DNDN) will host a ... 9:00 AM,ET (6:00 AM PT) to review the ... for Prostate AdenoCarcinoma Treatment, also known as D9902B),clinical ... immunotherapy for the treatment of advanced prostate,cancer., ...
... Burlington County, New Jersey is the newest study ... Hospital,of Philadelphia today received a contract to manage ... Children,s Hospital will manage local,participation, recruitment and data ... funded by the National Institutes of Health., ...
Cached Medicine Technology:Dendreon to Hold a Conference Call Today at 9:00 AM ET to Provide an Update on Interim Results of Phase 3 PROVENGE IMPACT Trial 2The Children's Hospital of Philadelphia Announces New Regional Participant in The National Children's Study 2
Single Use Loading Units (SULU's) with Titanium Staples for use with MULTIFIRE ENDO GIA™ 30 12 mm (Single Use Staplers with Titanium Staples)....
... The ENDOPATH EZ45 Thoracic Endoscopic Linear ... other minimally invasive surgical procedures for transection, ... be used with staple line buttressing materials ... be reloaded seven times for a total ...
... in Open Procedures with Compact Endoscopic Linear ... Cutter is designed to deliver a 45mm ... procedures, while simultaneously dividing the tissue between ... a standard blue cartridge, a thick-tissue green ...
ENDO CLIP II ML, 10 mm Pistol Grip Single Use Clip Applier with Medium - Large Super Interlock Titanium Clips...
Medicine Products: