Navigation Links
How much is the world spending on neglected disease research and development?
Date:2/4/2009

The first comprehensive survey of global spending on neglected disease R&D, published in this week's PLoS Medicine, finds that just over $US 2.5 billion was invested into R&D of new products in 2007, with three diseasesHIV/AIDS, TB, and malariareceiving nearly 80% of the total.

However, the survey finds that many neglected diseases, responsible for killing millions of people in developing countries, are significantly underfunded.

Researchers from The George Institute report that while HIV/AIDS, TB and malaria collectively received the majority of R&D funding, other diseases and disease categories each received less than 5% of global funding.

Sleeping sickness, leishmaniasis and Chagas disease collectively received only 4.9% of total global funding; the diarrhoeal illnesses surveyed collectively received 4.5% of global funding; the helminth (worm) infections received 2%; and bacterial pneumonia and meningitis received only 1.3%. Five diseases - leprosy, Buruli ulcer, trachoma, rheumatic fever, and typhoid and paratyphoid fever each received less than $10 million or 0.4% of total global investment. For many of these diseases, funding was not enough to create even one new product.

The need for R&D to develop new drugs and vaccines for preventing and treating neglected tropical infections in developing countries is widely accepted. For example, the creation of a vaccine for HIV/AIDS, more effective tools to diagnose TB, and better drug treatments for leishmaniasis and sleeping sickness would greatly improve health in the developing world. However, there has until now been an "information gap" for funders wishing to invest in this area.

In the new survey by Dr Mary Moran (The George Institute for International Health, Sydney, Australia) and colleagues, commissioned by the Bill and Melinda Gates Foundation, the researchers set out to fill this information gap. While specific R&D investment data were previously available for some neglected diseases, these cannot readily be compared since each survey used different methodologies and covered different diseases, products, donors, and countries. Moran and colleagues' survey was designed to include all neglected diseases and all control tools of significance to developing countries, and to gather funding data as consistently and comprehensively as possible.

The survey found that public and philanthropic donors collectively invested $US 2.3 billion (about 90%) of total funding in 2007. The US government represented nearly three quarters of global public spending. The largest organizational donors were the US National Institutes of Health (42% of total funding) and the Bill & Melinda Gates Foundation (18% of total funding). About a quarter of donor funding was routed to public-private product development partnerships (PDPs), such as the International AIDS Vaccine Initiative and the Medicines for Malaria Venture.

The survey's findings, say Moran and colleagues, suggests that "investment decisions are not only influenced by scientific or epidemiological considerations, but may also be influenced by factors such as the presence of advocacy and fundraising groups; by funder perceptions or preferences; or by the presence of policy frameworks and funding mechanisms that prioritise specific diseases."

The researchers also note that some of the world's wealthiest countries are "missing in action" from the top 10, top 20, or even top 50 funders of R&D for neglected diseases.

"A broadening of funding efforts," they say, "so that all who are able to contribute do so, and all diseases receive the attention they deserve, would lead to a dramatic positive impact on the health of developing country patients afflicted with these diseases."


'/>"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
Source:Eurekalert

Related medicine news :

1. Worlds First Website for Patients to Share Diagnostic-Quality Medical Images
2. Rotary Members Worldwide Prepare For Mass Immunization Campaigns In Polio-Endemic Countries
3. Wesley Mosley Selected to Participate in Global Youth Activation Summit During the 2009 Special Olympics World Winter Games
4. A World First in Minimally Invasive Robotic Surgery Promises a More Cost-Effective, Patiently Friendly Future
5. The Only 100% Biologically Pure Lycopene Cream in the World
6. World-renowned Instructor of the Healing Practice of Qigong to Teach in Los Angeles Mar. 7 & 8
7. Z Trim to Be Distributed to Meat and Poultry Industries by World Technology Ingredients
8. In the World of Germs, Man Bites Dog
9. Nano World Headquarters Positioned to Boost U.S. Economy
10. This February Discovery en Espanol Delves Into The Subconscious World of Attraction in Science of Sex Appeal
11. Worlds First Medical Identification Franchise Launches Nationally
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... City, Oklahoma (PRWEB) , ... June 25, 2016 ... ... helping both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic ... the Oklahoma City area —Johnson is one of the first doctors to perform ...
(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Story Highlights: ... the health care industry is causing providers to review ... Deloitte offers a suite of solutions for health care ... cost optimization: labor resource analysis, revenue cycle optimization and ... outcomes and better economics ...
(Date:6/24/2016)... Calif. , June 24, 2016  Global ... a biopharmaceutical company developing novel therapeutics for the ... needs, today announced the closing of its previously ... common stock, at the public offering price of ... the offering were offered by GBT. GBT estimates ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
Breaking Medicine Technology: