Navigation Links
How less can be more when treating some kidney cancers
Date:1/9/2008

ROCHESTER, Minn. -- A new Mayo Clinic study suggests that removing the entire kidney from younger patients with small kidney tumors may lead to decreased overall survival compared with an operation that removes the tumor but leaves the kidney intact. The study will be published in the February issue of the Journal of Urology.

Radical nephrectomy is a surgical procedure to remove the entire kidney along with the adrenal gland that sits atop the kidney and adjacent lymph nodes. In a partial nephrectomy, only the tumor is removed, sparing the surrounding normal kidney tissue.

For patients with small kidney tumors, removal of the entire kidney may be associated with long-term consequences that we did not previously recognize when compared to removal of just the tumor, says the studys lead author, R. Houston Thompson, M.D., a Mayo Clinic urologist currently serving a fellowship at Memorial Sloan-Kettering Cancer Center. Recent evidence suggests that there is a graded impact on survival based on declining overall kidney function. So as kidney function declines, the risk of heart attacks and heart-related events goes up, and consequently the risk of death from these events goes up.

In this retrospective study, the research team reviewed the cases of 648 Mayo Clinic patients who underwent either a partial or radical nephrectomy for a kidney tumor 4 centimeters or smaller. In the 327 patients younger than 65 years of age, radical nephrectomy was significantly associated with death from any cause when compared with partial nephrectomy. Ten-year overall survival rates were 82 percent for patients treated with a radical nephrectomy and 93 percent for patients treated with a partial nephrectomy.

We know the survival from cancer with partial nephrectomy or radical nephrectomy for patients with these small masses is excellent, says Michael Blute, M.D., a Mayo Clinic urologist and senior author of the study. Urologic surgeons need to consider long-term health consequences for patients with small renal mass undergoing complete nephrectomy.

According to Dr. Thompson, less than 25 percent of patients who are treated surgically for small kidney tumors undergo a partial nephrectomy in the United States. The fact that this is being performed in less than a quarter of cases raises a quality of care concern, he says, adding that more study is needed.


'/>"/>

Contact: Joel Streed
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Better access to cool caps improves outcomes, lowers cost of treating asphyxia in newborns
2. Treating Childhood Pneumonia at Home Could Save Lives in Developing Countries
3. Treating oft ignored non-cancer health issues after cancer diagnosis prolongs survival
4. Treating Depression Cuts Diabetes Death Risk
5. Doctors: Talk Therapy Newest Hope for Treating One Physical Side Effect of Holiday Blues
6. Treating patients with psychiatric disorders for hepatitis C
7. Treating your periodontal pockets may benefit your pocket book
8. Penn research shows transcranial magnetic stimulation effective in treating major depression
9. Subcutaneous administration of an antiemetic for treating vomiting caused by chemotherapy
10. PEGINTRON(TM) and REBETOL(R) Approved in European Union for Retreating Hepatitis C Patients Who Failed Previous Pegylated or Non-Pegylated Interferon Therapy
11. Study Shows Organons Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Clarkston, Michigan (PRWEB) , ... June 26, 2016 ... ... respect to fertility once they have been diagnosed with endometriosis. These women need ... but they also require a comprehensive approach that can help for preservation of ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented its ... Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor the outstanding ... Medicine Practice and Pediatric Emergency Medicine Practice. , “With this award, we ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 26, 2016 Story Highlights: ... models within the health care industry is causing providers ... , Deloitte offers a suite of solutions for ... impacting efficient cost optimization: labor resource analysis, revenue cycle ... facilitate better outcomes and better economics ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
Breaking Medicine Technology: