Navigation Links
How healthy are you for your age?
Date:5/22/2013

On May 22, JoVE will publish details of a technique to measure the health of human genetic material in relation to a patients age. The method is demonstrated by the laboratory of Dr. Gil Atzmon at New Yorks Albert Einstein College of Medicine. Dr. Atzmon hopes that the dissemination of this technique will lead to the development of a genetic thermometer to assess a patients health in relation to other individuals of the same age.

The JoVE publication will feature a technique that measures telomere length. Recently, telomeres have gained attention because they serve as caps to chromosomes. As such, they mark the ends of genetic material and ensure that genes do not degrade as cells divide. Starting with the first replication of DNA and division of a fertilized egg, chromosomes shorten because the DNA replication process is imperfect. Certain organs, like the stomach or skin, are composed of tissues that reconstitute themselves frequently. In these organs, and in young individuals, the telomerase enzyme extends telomeres with each division, negating chromosomal shortening that would otherwise occur. Telomerase activity declines as people age, and as a result telomeres shorten and can be responsible for age related afflictions and some cancers. Overall health can impact how quickly these telomeres degrade.

Think of telomere length as though it was a thermometer. It measures the health of your genetic material, Dr. Atzmon explains. It tells you how fit you are in relation to the age you are. If you have longer telomeres you are in good shape, if you have shorter telomeres you are less fit for your age and are not in good health.

Dr. Atzmon hopes that publication of this article will impact the ageing community by classifying health relative to an individuals age. I published in JoVE because I want more people to use the technique. As we [the medical community] collect more data, we can build a better index of age and health by population, and more accurately place a patient on the right spot in a continuum.

Adoption of this technique will allow clinicians to monitor a patients health as they are treated, by comparing telomere degradation of a sick patient to other patients with that disease and to determine if treatment is slowing degradation. Dr. Kira Henderson, JoVE Editor and Director of Review, explains, Telomere length and telomerase function impacts several realms of biological and medical research- from preventative aging models to cancer treatments. Maintaining the telomere is a pre-requisite to extending life and improving long-term health. It is our hope that the application of this JoVE video-article will elucidate relationships between disease state and telomere function and encourage advancement in this important field of study.


'/>"/>

Contact: Rachel Greene
press@jove.com
617-250-8451
The Journal of Visualized Experiments
Source:Eurekalert

Related medicine news :

1. Social ties have mixed impact on encouraging healthy behaviors in low-income areas
2. Life expectancy and healthy life years in the European Union, 2008-2010
3. Healthy Lifestyle Choices Could Cut Cancer Rates: Report
4. Healthy Behaviors Extend Life After Cancer, Experts Say
5. Healthy Weight Loss May Also Cut Your Cancer Risk
6. Study Redefines What a Healthy Vagina Is
7. Healthy Dieting in Pregnancy May Be Helpful
8. McMaster University researchers discover drug destroys human cancer stem cells but not healthy ones
9. Amazon Tribe Gives Clues to Heart-Healthy Lifestyles
10. Too much vitamin D can be as unhealthy as too little
11. Healthy Brain Connections Help Maintain Intellect in Old Age
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian ... On The Brink” is the creation of published author, William Nowers. Captain Nowers ... a WWII veteran, he spent thirty years in the Navy. Following his career ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
(Date:10/12/2017)... WAUSAU, Wis. (PRWEB) , ... October 12, 2017 ... ... formulated standard products to meet the demand of today’s consumer and regulatory authorities ... team of probiotic experts and tested to meet the highest standard. , ...
(Date:10/12/2017)... ... 2017 , ... The American College of Medical Informatics (ACMI) will present the ... Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... a pioneer in the field of medical informatics, this prestigious award is presented to ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... delivery system that we intend to develop to enable prevention of a major ... to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... Pa. , Oct. 10, 2017   West ... in innovative solutions for injectable drug administration, today shared ... West,s ID Adapter for improving the intradermal administration of ... Fourth Skin Vaccination Summit in May 2017 by Dr. ... Lead, Polio Department, World Health Organization (WHO), and recently ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare ... CPR training aide "cprCUBE" on Kickstarter. The device will ... during cardiac arrests with better efficiency compared to the ... offers real-time feedback on efficacy of the compression for ... campaign has a goal to raise $5,000. ...
(Date:10/2/2017)... Oct. 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... Software and Consulting, LLC , and named its founder ... based in Tennessee , will operate ... expands EnvoyHealth,s service offerings for health care partners to ... "In an interoperable world, technology ...
Breaking Medicine Technology: