Navigation Links
How genetics shape our addictions
Date:9/11/2012

This press release is available in French.

Have you ever wondered why some people find it so much easier to stop smoking than others? New research shows that vulnerability to smoking addiction is shaped by our genes. A study from the Montreal Neurological Institute and Hospital - The Neuro, McGill University shows that people with genetically fast nicotine metabolism have a significantly greater brain response to smoking cues than those with slow nicotine metabolism. Previous research shows that greater reactivity to smoking cues predicts decreased success at smoking cessation and that environmental cues promote increased nicotine intake in animals and humans. This new finding that nicotine metabolism rates affect the brain's response to smoking may lead the way for tailoring smoking cessation programs based on individual genetics.

Smoking cues, such as the sight of cigarettes or smokers, affect smoking behavior and are linked to relapse and cigarette use. Nicotine metabolism, by a liver enzyme, also influences smoking behavior. Variations in the gene that codes for this enzyme determine slow or fast rates of metabolism and therefore, the level of nicotine in the blood that reaches the brain. In the study smokers were screened for their nicotine metabolism rates and their enzyme genotype. Participants were aged 18 35 and smoked 5-25 cigarettes daily for a minimum of 2 years. People with the slowest and fastest metabolism had their brain response to visual smoking cues measured using functional MRI. Fast metabolizers had significantly greater response to visual cigarette cues than slow metabolizers in brain areas linked to memory, motivation and reward, namely the amygdala, hippocampus, striatum, insula, and cingulate cortex.

"The finding that nicotine metabolism rate has an impact on the brain's response to smoking cues supports our hy
'/>"/>

Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
McGill University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Optogenetics project takes top NIDA Addiction Science Award
2. Brave New World of Genetics Requires Safeguards, Experts Say
3. Odds of quitting smoking affected by genetics
4. Stanford study shows opiates side effects rooted in patients genetics
5. American Society of Human Genetics to hold 2012 annual meeting, Nov. 6 to 10, in San Francisco
6. Marin Countys high breast cancer rate may be tied to genetics
7. Genetics Society of Americas Genetics journal highlights for September 2012
8. More Babies Today Have Irregular Head Shape: Expert
9. New technique predictably generates complex, wavy shapes
10. Shape Up, Safely, for Summer
11. Dads Early Engagement With Son May Shape Behavior Later
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... Integrative Therapeutics has introduced two new ... cognition. , A unique combination of herbs and ... Flavonoid Complex apart from other antioxidant supplements. This ... support antioxidation versus the use of single or ... extract, Resveratrol, Alpha-Glycosyl Isoquercitrin, and Coenzyme Q10 with ...
(Date:4/24/2015)... National Access Cannabis (NAC), ... to medical cannabis, is taking a leadership role in ... patients. , NAC is the first to back mdBriefCase ... grant, NAC will be providing 300 healthcare professionals with ... to help Canadians gain safe and responsible access to ...
(Date:4/24/2015)... Boone, Iowa (PRWEB) April 24, 2015 Eastern ... the facility’s new Community Room on Sunday April 26th from ... are invited to attend the ribbon cutting and grand opening ... and staff will be on hand to offer tours to ... care retirement community. , The new community room will be ...
(Date:4/24/2015)... 24, 2015 Recent research by the ... Physical therapists and their assistants are among the top ... growth by the year 2023. , Physical therapists ... strongest growth and greatest potential for expansion in the ... revealed that while physical therapists can offer great relief ...
(Date:4/24/2015)... A group of Southern Americans will take advantage of a ... Chinese for two weeks from July 21 to August 5, ... be challenged to avoid conflicts due to cultural differences, ideological ... required to function as one team, living and traveling together ... and Kung Fu martial arts as a part of this ...
Breaking Medicine News(10 mins):Health News:Integrative Therapeutics Introduces Two ProThrivers™ Wellness Supplements with Specialty Ingredients from Kyowa Hakko USA 2Health News:Integrative Therapeutics Introduces Two ProThrivers™ Wellness Supplements with Specialty Ingredients from Kyowa Hakko USA 3Health News:Integrative Therapeutics Introduces Two ProThrivers™ Wellness Supplements with Specialty Ingredients from Kyowa Hakko USA 4Health News:National Access Cannabis Gives 300 Canadian Healthcare Professionals Access to Medical Cannabis Certificate Program 2Health News:Huntsville Medical Doctor Explains Why Physical Therapy May Not Treat Muscle Numbness Adequately 2Health News:Inside China: Americans Travel to Heartland of China to Live & Learn with Local Chinese 2Health News:Inside China: Americans Travel to Heartland of China to Live & Learn with Local Chinese 3
... no difference in cognition between hormones and placebo , , ... to women in the first few years after menopause ... sexual interest, a new study found. , The ... plus progesterone, suggesting that progesterone could be the active ...
... Solution to Large Corporations, NEW YORK, Sept. ... that it has hired Bill McDermott as Executive,Vice ... named a member of the,company,s Executive Management Committee. ... for Fortune 1000 companies. The,announcement was made by ...
... Sept. 24 Orthopedic Development,Corporation, parent company to ... received the TruFUSE posterior fusion procedure,since its introduction ... solutions to treat intractable back pain, has been ... small cork-shaped dowels made of human,bone, called allografts, ...
... Minn., Sept. 24 Enova Medical Technologies,and Stille ... to announce that,they have entered into a strategic ... of 2007, Stille will market Enova,s,breakthrough LED cordless ... Scandinavia, Great Britain and Italy and, on a ...
... Sterling Life,Insurance Company, a subsidiary of Aon ... has received approval from the Centers for Medicare ... Medicare,Advantage private-fee-for-service (PFFS) plans. This announcement follows,the statement ... review and,determined that Sterling Life Insurance has demonstrated ...
... Radio and Print Ads Debut Nationwide in October ... YORK, Sept. 24 /PRNewswire-USNewswwire/ -- Using a mix ... of cell phone gossip, bold new,TV, radio and ... Access,encourages urban teens to rethink their perception of ...
Cached Medicine News:Health News:HRT: A Boost for Libido, But Not Memory 2Health News:HRT: A Boost for Libido, But Not Memory 3Health News:AXA Equitable Life Insurance Co. Hires William McDermott to Lead Corporate Retirement Planning Business 2Health News:AXA Equitable Life Insurance Co. Hires William McDermott to Lead Corporate Retirement Planning Business 3Health News:Orthopedic Development Corporation's TruFUSE(R) Procedure Tops 1,750 Patients in First Year 2Health News:Stille and Enova Form Strategic Partnership to Introduce World's Brightest LED Cordless Surgical Headlights Into Europe and Japan 2Health News:Sterling Life Enhances Marketing Operations Controls to Better Serve Medicare Beneficiaries 2Health News:Sterling Life Enhances Marketing Operations Controls to Better Serve Medicare Beneficiaries 3Health News:Prime Access Creates Groundbreaking Ads Targeting Urban Teens for the White House's National Youth Anti-Drug Media Campaign 2Health News:Prime Access Creates Groundbreaking Ads Targeting Urban Teens for the White House's National Youth Anti-Drug Media Campaign 3
(Date:4/24/2015)... BUENA, N.J. , April 24, 2015  IGI ... Jersey based specialty generic pharmaceutical company, announced ... pm ET on Tuesday, April 28, 2015 to discuss ... invites you to listen to the call by dialing ... call 1-855-669-9657.  Participants should ask to be joined into ...
(Date:4/24/2015)...   Vestagen Technical Textiles, Inc. today announced ... recently received two notable innovation awards. The first is ... innovations with potential to create a positive impact in ... New York City , VESTEX received the ... Safety" category. The awards honor excellence in new product ...
(Date:4/24/2015)... and Markets ( http://www.researchandmarkets.com/research/pmbmv2/global_biobanking ) has announced ... report to their offering. The analysts ... CAGR of 7.07% over the period 2014-2019 ... segments: Equipment and Consumables. This report covers the present ... market for the period 2015-2019. ...
Breaking Medicine Technology:VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 2VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 3Global Biobanking Market Report 2015-2019 - Increase in Strategic Collaborations with Beckman Coulter, Tecan & Thermo Fischer Scientific Dominating 2
... Innovation ... 25 Cleveland Clinic is hosting two,upcoming Summits that will ... -- Oct. 1-3: Innovation is driving the development of new ... cardiovascular disease. The 5th annual ...
... Findings from an international,multicenter, randomized, double-blind, placebo-controlled ... treatment of moderate to severe,plaque psoriasis will be ... meeting,of the World Congress of Dermatology, which takes ... Buenos Aires, Argentina. The presentation, entitled CNTO ...
Cached Medicine Technology:Cleveland Clinic Summits to Focus on Cardiovascular Medical Innovation 2Cleveland Clinic Summits to Focus on Cardiovascular Medical Innovation 3Pivotal Ustekinumab (CNTO 1275) Phase 3 Data to Debut at World Congress of Dermatology Meeting 2
The double action wire cutter has both side and end cutting capabilities....
... system is a combination Spectral Optical Coherence ... system that provides suberb, high-quality images of ... the advancements of spectral technology, OTI's sytem ... 27,000 A-Scans per second and provide images ...
... cryoconsole and platform technology as Freezor to ... Arctic Circler is an ablation tool designed ... rely on medication., ,With its elegant ... ability to create curvilinear lesions rapidly within ...
The KMedic Jet Wire Twister is designed to provide fast, smooth and even twisting of soft wire, saving time in the O.R. Now available for the first time in stainless steel. Suitable for the entire ra...
Medicine Products: