Navigation Links
How does aging affect cancer? Einstein awarded $2.8m grant to answer NCI 'provocative question'
Date:10/21/2013

October 21, 2013 -- (BRONX, NY) -- Gene mutations increase as people age, which helps explain why cancer usually strikes older people. But what other consequences of aging promote cancer development or protect against it?

This is one of the 24 "Provocative Questions" that the National Cancer Institute (NCI) wants researchers to address. Now, a team of scientists at Albert Einstein College of Medicine of Yeshiva University has received a $2.8 million grant from NCI to investigate this question. The researchers will examine the role of epigenetics in causing lung cancer in people of different ages.

Epigenetic changes involve chemical "tags" that turn genes on or off without affecting the genes' underlying DNA sequences. As with gene mutations, epigenetic tags accumulate with age, and their presence on genes can be influenced by environmental factors such as what you eat and the quality of the air you breathe. Scientists now recognize that aberrant epigenetic tagging plays a major role in causing many types of cancer, but just how epigenetic changes influence cancer risk still isn't well understood.

The grant award will allow Einstein researchers to focus on a vexing question related to smoking risk.

"Why do some smokers get lung cancer in their 40s while others who smoke their whole lives are protected until very old age?" asked Jan Vijg, Ph.D., professor and chair of genetics and the Lola and Saul Kramer Chair in Molecular Genetics at Einstein and co-principle investigator on the grant. "We will look at how a person's epigenome the entire set of chemical tags that decorate their genes modulates the effect of aging on lung cancer risk."

Dr. Vijg, along with co-principal investigators

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Learning new skills keeps an aging mind sharp
2. Anti-Wrinkle and Anti-Aging Ingredients Featured in Face Whisperer® Line from Sublime Beauty® on Sale
3. Aging expert Colin Milner addresses United Nations' findings by offering "Nine Principles" for improving society's response to population aging
4. Medical imaging professionals develop safety checklist to improve pediatric radiography
5. Over-the-Counter As Effective As Rx at Managing Post-Tonsillectomy Pain
6. Over-the counter as effective as Rx at managing post-tonsillectomy pain
7. mHealth Alliance and Pfizer Call for Collective Action on Mobile Health for Healthy Aging
8. Global Metal Packaging Industry
9. Global Medical Imaging Reagents Market 2016 Forecast Report Now Available at ReportsnReports.com
10. Kollagen Intensiv the Newest Natural Formula is Now Available to Reduce the Appearance of Aging Signs, Dark Circles and Wrinkles
11. Join GSA in New Orleans for the nations premier aging conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... 30, 2014 August 28th, 2014: ... in our society and the toll that takes on ... vital that continuing education for physical therapists addresses this ... physical therapists help others, Hands-On Seminars is offering discounts ... , Three learning styles are available to fit the ...
(Date:8/30/2014)... When a prominent bank reveals a successful cyber attack, ... 27th, when news began surfacing about the FBI probing ... and at least one other bank. But when news gets ... seven prominent banks , everyone starts thinking about their own ... quickly goes viral. Bloomberg followed up on Friday with ...
(Date:8/30/2014)... Columbus, Ohio (PRWEB) August 30, 2014 As ... serioius birth defect when give to pregnant mothers, Wright & ... District Judge Cynthia M. Rufe. The remand in ... are representative of 18 states and are involved in one ... allows them to have their Zoloft birth defect lawsuit sent ...
(Date:8/30/2014)... Barton Associates, an industry leading physician, ... , announces a new office location in Keene, NH, ... headquartered in Peabody, MA, with additional staffing centers in ... Jupiter, FL. , Barton Associates made the decision to ... crisis affecting the United States, a crisis that will ...
(Date:8/30/2014)... Saturday 30 August 2014: The first multidisciplinary recommendations ... acute coronary syndromes (ACS) are published today in ... was written jointly by the European Heart Rhythm ... and the European Association of Percutaneous Cardiovascular Interventions ... Bulent Gorenek (Turkey), chairperson of the task force, ...
Breaking Medicine News(10 mins):Health News:Leader in Manual Therapy Continuing Education Makes it Easier for Physical Therapists to Improve Results on Patients 2Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 2Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 3Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 4Health News:Big Name Bank Hacks Highlight the Importance of Regular Testing and Effective Emergency Response 5Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 2Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 3Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 4Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 5Health News:Barton Associates to Open a New Office Location in Keene, NH 2Health News:First multidisciplinary recommendations on management of arrhythmias in ACS patients 2
... 10 The Council for American Medical Innovation today ... Collins to head the National Institutes of Health (NIH). ... ) , , "Dr. Collins is ... pioneer in medical innovation," said Council President Dick Gephardt. ...
... July 10 Americans United for Life (AUL) announced today ... called to testify at the confirmation hearings for Judge Sonia ... AUL President Charmaine Yoest said "We are honored to have ... nomination of Judge Sotomayor to the highest court in the ...
... Germany, July 10 The supervisory board of Celesio ... per cent in pharmaceutical wholesaler Panpharma. This step into ... world-wide is part of Celesio,s growth strategy. Celesio doesn,t ... , Celesio spent about two years thoroughly analysing ...
... Healthy reaction to mental stress not seen in those with ... News) -- Anger and other forms of mental stress cause ... blood to the brain in healthy people, but this doesn,t ... finding of U.S. researchers who used ultrasound imaging to monitor ...
... months of protests, media coverage and online uproar, Oscar ... mental health organization, and Kipp Berdiansky, co-owner of the ... to discuss mental illness, the associated stigma and the ... Berdiansky and Jordan Zweigoron opened Psycho Donuts in March ...
... Aegis of Granada Hills has been named "Best Assisted Living Facility" ... annual Readers Choice Awards. This is the second year in a ... In voting, Aegis was a write-in candidate and received more ... area to gain top status. , , "We ...
Cached Medicine News:Health News:Council for American Medical Innovation Applauds Appointment of Geneticist Francis Collins to Head National Institutes of Health 2Health News:Americans United for Life President to Testify at Sotomayor Senate Judiciary Hearing 2Health News:Celesio Acquires Majority Stake in Number One Brazilian Pharmaceutical Wholesaler Panpharma 2Health News:Blood Rush to the Brain When Angry Is a Good Sign 2Health News:There Is No Way to Sugar Coat These Donuts 2
(Date:8/29/2014)... , Aug. 29, 2014 Diseases largely ... a generation ago are returning. Measles was declared eliminated ... in 2014 as of August 15—the highest incidence in ... public health department declared whooping cough a problem of ... are getting sick and dying from these preventable diseases—in ...
(Date:8/29/2014)... DUBLIN , Aug. 29, 2014 ... the "Global Multiple Sclerosis Drugs Market 2014-2018" ... is a chronic, inflammatory medical condition that results in ... damaged because of an abnormal response by the immune ... (CNS). It is a potentially debilitating disease in which ...
(Date:8/29/2014)... Calif. , Aug. 29, 2014  Pacific Medical ... its new website design . The main website, ... that showcases the company,s new services and content relevant ... implementing a new streamlined design, viewers can now better ... for health care practices and create a more visible ...
Breaking Medicine Technology:Vaccines at the Crossroads: Outbreaks On the Rise Across America 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 3Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 2Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 3PMDS Announces New Website 2
... Research and Manufacturers of America (PhRMA) today announced the ... Directors. "We are pleased to welcome four ... said PhRMA President and Chief Executive Officer John J. ... sectors in the U.S., they bring to the table ...
... Dec. 21, 2010 Reportlinker.com announces that a ... catalogue: Thai Self-monitoring of Blood ... http://www.reportlinker.com/p0350305/Thai-Self-monitoring-of-Blood-Glucose-SMBG-Devices-and-Strips-Market.html This Market ... the dynamics of blood glucose monitoring device sales ...
Cached Medicine Technology:PhRMA Elects Four New Members to Board of Directors 2PhRMA Elects Four New Members to Board of Directors 3
... contains primers and a FAM-labeled probe that ... gene. In addition, this ASR contains primers, ... internal control sequence. This ASR requires an ... Red reporter dyes such as the Cepheid ...
...
Reptilase-Time from Bothrops atrox...
Thrombin Activatable Fibrinolysis Inhibitor Assay Kit...
Medicine Products: