Navigation Links
How do Lactobacilli treat Helicobacter pylori-related diseases?
Date:9/9/2008

Some studies have demonstrated H. pylori stimulates the release of interleukin-8 (IL-8) from gastric epithelia, which initiates inflammatory damage to gastric mucosa and plays a crucial role in the pathogenesis of H. pylori infections. H. pylori lipopolysaccharide (H. pylori-LPS) is the major initiator in H. pylori-induced IL-8 production via activation of Toll-like receptor 4 (TLR4) pathway in gastric epithelia. Considering the novel finding that H. pylori is an indigenous biota in gastric microflora including Lactobacilli and hypothesis that the disturbance of gastric microecosystem plays a more important role in pathogenetic mechanisms of H. pylori, the eradiation of H. pylori doesn't seem justified to everyone. The speculation on validity of restoration of the gastric microecosystem has been demonstrated by therapeutic effects of Lactobacilli administration on H. pylori-associated diseases. But whether Lactobacilli inhibit H. pylori-LPS-induced IL-8 production through blocking H. pylori-LPS-activated TLR4 pathway hasn't been well researched.

A research article to be published on August 28, 2008 in the World Journal of Gastroenterology addresses this question. The research team led by Prof. Hong-Sheng Ma from West China Hospital of Sichuan University treated SGC-7901 cells with H. pylori Sydney strain 1 lipopolysaccharide (H. pyloriSS1-LPS) in the absence or presence of a pretreatment with viable Lactobacillus bulgaricus (LBG). The results indicated that viable LBG prevented H. pyloriSS1-LPS-activated TLR4 pathway in SGC-7901 cells, leading to its inhibitory effect on IL-8 production stimulated by H. pyloriSS1-LPS. Considering some evidence implied that supernatant recovered from Lactobacilli culture MRS broth contained some latent soluble proteins secreted by Lactobacilli, SGC-7901 cells were treated wi
'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. A potential approach to treatment of hepatitis B virus infection
2. Gulf Coast Dialysis Caregivers, Volunteers Brace for Hurricane Ike; Prepare to Maintain Power, Continued Access for Patients to Life-Saving Treatment
3. Blood Pressure Treatment Can Be Used Against Stroke
4. Young African-American Males Face Mental Health Crisis; Experts Call For New Treatment Strategies and Better Access to Care
5. Hospitals Participating in Get With The Guidelines(SM) Program Follow Heart Attack Treatment Guidelines Better Than Others
6. Drug Re-Sensitizes Breast Tumors to Treatment
7. Age Spots Are No Match for Cosmetic Dermatology Treatments
8. Important Information on Fibromyalgia and Access to Treatments
9. PET scans lead to treatment changes in majority of colorectal cancer patients
10. 13% of Seniors Report Being Mistreated
11. First Major Medical Meeting Convening for MRI-guided Focused Ultrasound to Treat Cancer, Stroke, Fibroids, Other Conditions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... This report provides quantitative analysis ... The analysis includes market size data by revenue ... company share data by revenue in 2013 for ... It uses data and information sourced from proprietary ... , Scope,     Information on market ...
(Date:7/14/2014)... (PRWEB) July 14, 2014 BCC ... report, SYNTHETIC BIOLOGY: GLOBAL MARKETS , the ... to nearly $11.9 billion in 2018, with a ... Enabled products account for the fastest growing segment, ... CAGR. Synthetic biology-enabled products in the pharmaceutical/diagnostics, chemical, ...
(Date:7/14/2014)... July 14, 2014 Secure Decisions, a ... is partnering with the Software Assurance Marketplace (SWAMP) to ... the software that drives everyday life. , The SWAMP, ... housed in the Morgridge Institute for Research, is funded ... advance software security practices by building a free facility ...
(Date:7/14/2014)... Clearwater, Florida (PRWEB) July 14, 2014 ... Summer Open House event will be held at the ... Wednesday July 16th from 4-8pm. Wine and other refreshments ... advantage of retail discounts on beauty products ... skin treatment known as dermaplaning. , Dermaplaning (also ...
(Date:7/14/2014)... July 14, 2014 The Encino ... now offering Lumineers and porcelain veneers. These ... that require more preparation and greater loss of healthy ... shells to conceal visible flaws on the tooth. Encino ... closely with patients to ensure they offer the most ...
Breaking Medicine News(10 mins):Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 2Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 3Health News:Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com 4Health News:Global Market for Synthetic Biology to Reach Nearly $11.9 Billion by 2018 — Enabled Products Account for the Fastest Growing Segment with 36.7% CAGR 2Health News:Global Market for Synthetic Biology to Reach Nearly $11.9 Billion by 2018 — Enabled Products Account for the Fastest Growing Segment with 36.7% CAGR 3Health News:Madison-based SWAMP, Secure Decisions partner to enhance software security 2Health News:Madison-based SWAMP, Secure Decisions partner to enhance software security 3Health News:Botanica Day Spa to Feature Dermaplaning at Upcoming Open House 2Health News:Botanica Day Spa to Feature Dermaplaning at Upcoming Open House 3Health News:Encino Esthetic Dental Group is Now Offering Lumineers and Porcelain Veneers 2
... finds cavities before X-rays allowing, dentists to ... TORONTO, July 3 /PRNewswire/ - Quantum Dental ... technology which,detects and monitors the early onset of ... reduces the number of invasive and painful procedures,and ...
... G8 failure on food prices, biofuels, and climate ... world,s population - at risk of hunger, warns,anti-poverty ... ahead of the G8,summit in Hokkaido, Japan, ActionAid ... has Contributed to the Global Food Crisis and ...
... completely fabricated,item about GO3 Omega-3 fish oil capsules ... Star magazine, none of the parties named in ... magazine prior to publication., (Photo: http://www.newscom.com/cgi-bin/prnh/20080702/LAW528 ... and will vigorously pursue any,organization making false claims ...
... Roger Mason Jr,Washington Wizards Guard and Washington, ... a Cause on July 29 featuring bowling at ... coming out to support the,cause, including Brendan Haywood ... Anthony, Allen Iverson, Vince Carter, Kevin Durant, and,Chris ...
... Technology could one day help tailor treatments to individual patients, ... new technique for finding and analyzing stray cancer cells in ... for doctors to one day not only determine the genetic ... cells and adjust treatments accordingly. , "I think this ...
... John Albright, MD, will join three other physicians as a 2008 ... , ... Orlando, Florida (PRWEB) July 2, 2008 -- ... three other physicians as a 2008 American Orthopaedic Society for ...
Cached Medicine News:Health News:Breakthrough Technology That Will Revolutionize the Treatment of Tooth Decay 2Health News:Breakthrough Technology That Will Revolutionize the Treatment of Tooth Decay 3Health News:ActionAid Challenges G8 on Response to Food Crisis 2Health News:GO3 Statement Regarding Erroneous Coverage in Star Magazine 2Health News:Washington Wizards Guard Roger Mason Jr. to Host Bowling at Lucky Strike to Benefit National Kidney Foundation of the National Capital Area 2Health News:Circulating Tumor Cells Reveal Insights Into Lung Cancers 2Health News:Circulating Tumor Cells Reveal Insights Into Lung Cancers 3Health News:Renowned Iowa Orthopaedic Surgeon, John Albright, MD, Inducted into Sports Medicine Hall of Fame 2Health News:Renowned Iowa Orthopaedic Surgeon, John Albright, MD, Inducted into Sports Medicine Hall of Fame 3
(Date:7/14/2014)... , July 14, 2014 Lumin Medical ... the assets of PatientTrak, the leading provider of on-demand ... from Illinois to ... is Lumin which means light and our mission is ... patient satisfaction, increase efficiencies and reduce costs," said ...
(Date:7/14/2014)... N.J. , July 14, 2014  Invivotek ... LLC is pleased to announce that its animal ... Association for the Assessment and Accreditation of Laboratory ... treatment of animals in science worldwide through voluntary ... standards for animal care and use in 38 ...
(Date:7/14/2014)... 14, 2014  Remedy Informatics, the leading provider ... and life sciences research, announced that it has ... to build the first-ever national patient registry devoted ... pancreatitis. "The National Pancreas Foundation is ... thoughtful and committed organizations can effect upon society ...
Breaking Medicine Technology:Lumin Medical Purchases PatientTrak 2Lumin Medical Purchases PatientTrak 3Invivotek Awarded Full AAALAC Accreditation for Excellence in Laboratory Animal Care and Use 2Remedy Informatics Partners with National Pancreas Foundation to Build a National Patient Registry 2Remedy Informatics Partners with National Pancreas Foundation to Build a National Patient Registry 3
... 4, 2012  Elevation Pharmaceuticals, Inc. announced today the closing ... investor Novo Ventures , to fund development of Elevation,s ... disease (COPD). All previous investors participated in the round, including ... Capital and Mesa Verde Venture Partners . In ...
... 4, 2012 /PRNewswire-iReach/ -- DFH Pharma, ... focused exclusively in the HIV-1 therapeutic space, announced ... medicinal chemistry services to support DFH efforts to ... drugs. Maturation inhibitors are a novel class of ...
Cached Medicine Technology:Elevation Pharmaceuticals Completes $30 Million Series B Financing to Advance Aerosol COPD Therapy 2Elevation Pharmaceuticals Completes $30 Million Series B Financing to Advance Aerosol COPD Therapy 3DFH Pharma to Collaborate with CiVentiChem to Develop Second-Generation HIV Maturation Inhibitor Drugs 2DFH Pharma to Collaborate with CiVentiChem to Develop Second-Generation HIV Maturation Inhibitor Drugs 3
Round knurled handle. Overall length 130 mm....
Optimum Extra Strength cleaner is a sterile non-preserved cleaning solution for use with fluorosilicone acrylate and silicone acrylate rigid gas permeable (RGP) and all hard contact lenses of any pol...
Round knurled handle. Overall length 130 mm....
Hosford foreign body spud 4 3/4 inches, gouge blade 1 x 7 mm rounded tip, angled to left....
Medicine Products: