Navigation Links
How dark chocolate may guard against brain injury from stroke
Date:5/5/2010

Researchers at Johns Hopkins have discovered that a compound in dark chocolate may protect the brain after a stroke by increasing cellular signals already known to shield nerve cells from damage.

Ninety minutes after feeding mice a single modest dose of epicatechin, a compound found naturally in dark chocolate, the scientists induced an ischemic stroke by essentially cutting off blood supply to the animals' brains. They found that the animals that had preventively ingested the epicatechin suffered significantly less brain damage than the ones that had not been given the compound.

While most treatments against stroke in humans have to be given within a two- to three-hour time window to be effective, epicatechin appeared to limit further neuronal damage when given to mice 3.5 hours after a stroke. Given six hours after a stroke, however, the compound offered no protection to brain cells.

Sylvain Dor, Ph.D., associate professor of anesthesiology and critical care medicine and pharmacology and molecular sciences at the Johns Hopkins University School of Medicine, says his study suggests that epicatechin stimulates two previously well-established pathways known to shield nerve cells in the brain from damage. When the stroke hits, the brain is ready to protect itself because these pathways Nrf2 and heme oxygenase 1 are activated. In mice that selectively lacked activity in those pathways, the study found, epicatechin had no significant protective effect and their brain cells died after a stroke.

The study now appears online in the Journal of Cerebral Blood Flow and Metabolism.

Eventually, Dor says, he hopes his research into these pathways could lead to insights into limiting acute stroke damage and possibly protecting against chronic neurological degenerative conditions, such as Alzheimer's disease and other age-related cognitive disorders.

The amount of dark chocolate people would need to consume to ben
'/>"/>

Contact: Stephanie Desmon
sdesmon1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Yogen Fruz Introduces New Holiday Flavors: Yog-Nog and Mint Chocolate Chip
2. Dark Chocolate May Lower Stroke Risk
3. Can Chocolate Lower Your Risk of Stroke?
4. Last-minute Valentines Day Idea: Free E-Book of Classic Chocolate Available for Download from SBI Publishing
5. Chocolate lovers could be lowering their risk of stroke: Study
6. Chocolate Industry Leaders Sign Agreement, Align on Path Towards Increasing Consumer Availability & Consistency of Beneficial Cocoa Flavanols
7. Chocolate May Make Some Strokes Less Likely
8. A Little Chocolate May Do the Heart Good
9. Chocolate a Sweet Pick-Me-Up for the Depressed
10. Guard RFID Solutions Inc. and VT Milcom Enter into Distribution Agreement
11. Nuclear Power Plant Improves Site Security with Blast Resistant Guard Booth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... As reported by GantDaily.com in the article ... Trends , Outbreaks (8/20), the National Institute on Drug Abuse ... abuse trends by turning to social media. As NIDA currently ... is also working with the University of Maryland to create ... System, which will be funded by the National Institute of ...
(Date:8/29/2014)... Orlando, Florida (PRWEB) August 29, 2014 Formed ... men with talents well beyond their years. Their sophisticated ... avid pop music listener is fortunate enough to experience every ... to leave their audience uplifted and feeling loved with the ... When asked specifically about this, the group unanimously replied - ...
(Date:8/29/2014)... 2014 Healthpointe is pleased to ... Therapy students via Clinical Rotations. Physical ... shadowing Healthpointe providers and specialists throughout their daily ... clinical experience and learn professional preparation. ... insight into several patient care techniques and expand ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 Carson Hearing ... to provide hearing health care tips to local residents ... blog section will offer weekly articles from the audiologists ... topics including the latest advances in hearing restoration research, ... questions. The audiologists plan to write a new post ...
(Date:8/29/2014)... August 29, 2014 - Despite US Preventive Services ... are many barriers, several of which may be ameliorated ... researchers at NYU Langone Medical Center published online August ... Medicine ( JGIM ). , David Levine, MD, ... Internal Medicine at NYU Langone, and colleagues found that ...
Breaking Medicine News(10 mins):Health News:Social Media Proves to Be Helpful in Fighting Drug Abuse 2Health News:Social Media Proves to Be Helpful in Fighting Drug Abuse 3Health News:KAJ Brothers Commits $10,000 to International Justice Mission To End Human Sex Trafficking and Challenges Other Artists and Celebrities To Do Likewise 2Health News:KAJ Brothers Commits $10,000 to International Justice Mission To End Human Sex Trafficking and Challenges Other Artists and Celebrities To Do Likewise 3Health News:KAJ Brothers Commits $10,000 to International Justice Mission To End Human Sex Trafficking and Challenges Other Artists and Celebrities To Do Likewise 4Health News:Healthpointe is Now Offering Clinical Rotations for Chapman University Physical Therapy Students 2Health News:Fort Worth Hearing Aid Leader, Carson Hearing Care, Creates Expert Blog to Discuss Important Hearing Healthcare Topics 2Health News:Fort Worth Hearing Aid Leader, Carson Hearing Care, Creates Expert Blog to Discuss Important Hearing Healthcare Topics 3Health News:Options for weight loss your primary care doctor might not know about 2
... show no lifesaving benefit over bare-metal version, studies show ... arteries propped open by drug-coated stents are less likely ... stents, the risk of death and heart attacks is ... Sweden and the United States show. , The Swedish ...
... Week 2009, Home Care Delivered reinforces programs designed to support clinicians ... ... VA (Vocus) May 6, 2009 -- In conjunction with the American ... observed annually from May 6th through 12th. The week begins with ...
... Contributions emphasize need for improved mental health services ... The Regence Foundation announced today it awarded $390,000 ... Idaho, Oregon, Utah and Washington. Five of the ... organizations nominated by Regence employees as part of ...
... 6 Cardinal Health, a global provider of ... productivity of health care, today announced its board ... shareholders to vote on a proposed employee stock ... 99th consecutive regular quarterly dividend.The proposed option exchange ...
... now has within its reach the potential to end ... in Geneva, the Board of Directors of the Global ... today agreed to enhance the Fund,s response to HIV/AIDS ... mother-to-child transmission of HIV (PMTCT), thereby opening the door ...
... Alliance Calls for Cross-Sector Solutions, Releases Strategy ReportWASHINGTON, ... the pharmaceutical industry, patients, consumer groups, and drug ... to counter the continued rise in prescription drug ... result of a combination of factors and can ...
Cached Medicine News:Health News:Drug-Coated Stents Better at Keeping Arteries Open 2Health News:Drug-Coated Stents Better at Keeping Arteries Open 3Health News:Home Care Delivered, Inc. Celebrates National Nurses Week 2009 in Recognition of America's 2.9 Million Registered Nurses 2Health News:Regence Foundation Grants $390,000 to Improve Health Care Safety Net 2Health News:Regence Foundation Grants $390,000 to Improve Health Care Safety Net 3Health News:Cardinal Health Board Proposes Employee Stock Option Exchange Program, Declares Regular Quarterly Dividend 2Health News:Cardinal Health Board Proposes Employee Stock Option Exchange Program, Declares Regular Quarterly Dividend 3Health News:Cardinal Health Board Proposes Employee Stock Option Exchange Program, Declares Regular Quarterly Dividend 4Health News:Cardinal Health Board Proposes Employee Stock Option Exchange Program, Declares Regular Quarterly Dividend 5Health News:GAA Applauds Global Fund's Decision to Accelerate Support for Treatment Strategies to Prevent Mother-to-Child Transmission of HIV 2Health News:Prescription Drug Abuse Poses Public Health Threat 2
(Date:8/29/2014)... Aug. 29, 2014  Abaxis, Inc. (NasdaqGS: ... instrumentation and consumables to the medical, research and veterinary ... and Chief Executive Officer, will present at the CL ... on Tuesday, September 9, 2014 at 12:30 p.m. ET. ... Place Hotel in New York City ...
(Date:8/29/2014)... Research and Markets  has announced the addition of ... 2014-2018" report to their offering. ... connect, support, or surround bones. There are several types ... fascia, and other fibrous tissues. Repetitive use, accidents, injuries, ... in wear and tear in these tissues. Orthopedic soft ...
(Date:8/28/2014)... 28, 2014  Rigrodsky & Long, P.A.: , ... (NYSE: LCI )? , Did you purchase your ... July 16, 2014, inclusive? , Did you lose money ... you want to discuss your rights? ... Attorney, Timothy J. MacFall , announces that a complaint has ...
Breaking Medicine Technology:Abaxis, Inc. to Present at CL King's 12th Annual Best Ideas Conference 2014 2Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 2Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 3Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 2Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 3
Sprint Quattro Secure™ is a Steroid-Eluting, True Bipolar, Active Fixation ICD Lead....
TVL defibrillation leads have a patented coiled-coil design for faster, easier insertion and more precise intracardiac placement. Designed with an integrated bipolar design, the lead enables high-vol...
The TVL-ADX lead is a thin, high-performing defibrillation lead that offers a true bipolar configuration designed for smarter sensing and low defibrillation threshold for greater patient safety margi...
... SPL defibrillator lead features a ... the flexibility and maneuverability of ... the physician who prefers a ... the SPL lead also promotes ...
Medicine Products: