Navigation Links
How can evolutionary biology explain why we get cancer?
Date:1/22/2013

Over 500 billion cells in our bodies will be replaced daily, yet natural selection has enabled us to develop defenses against the cellular mutations which could cause cancer. It is this relationship between evolution and the body's fight against cancer which is explored in a new special issue of the Open Access journal Evolutionary Applications.

"Cancer is far from a single well-defined disease which we can identify and eradicate," said Dr Athena Aktipis, Director, Human and Social Evolution, Center for Evolution and Cancer at the University of California, San Francisco. "It is highly diverse and evolutionary theory allows us to consider cancer as a highly complex and evolving ecosystem. This approach can improve the understanding, treatment and prevention of a number of different cancer types."

By applying the principles of evolutionary biology papers in the special issue ask: Why do we get cancer, despite the body's powerful cancer suppression mechanisms? How do evolutionary principles like natural selection, mutation, and genetic drift, work in a cancer ecosystem? How can we use evolutionary theory to minimize the rate of cancers worldwide?

"Nowhere is the diversity of cancer better revealed than the many reasons why we remain vulnerable to it," said Dr Aktipis. "Evolutionary medicine allows us to see explanations for traits that leave organisms vulnerable to disease."

These evolutionary explanations include the role of environmental factors, such as the relationship between tobacco availability and lung cancer; co-evolution with fast evolving pathogens; constraints on what selection can do; trade-offs, such as the capacity for tissue repair vs. risk of cancer; reproductive success at the expense of health; defenses with costs as well as benefits, such as inflammation.

"An evolutionary approach can unite and explain the many avenues of cancer research by allowing us to see cancer as an ecosystem," concluded Dr Aktipis. "Just as a forest depends on the individual characteristics of trees as well as the interactions of each tree with its environment; similarly tumors can be comprised of genetically distinct cells, which depend on both cell-to-cell interactions within the tumor, as well as on the interactions of tumor itself with the body."


'/>"/>

Contact: Ben Norman
sciencenewsroom@wiley.com
44-012-437-70375
Wiley
Source:Eurekalert

Related medicine news :

1. Dr. Harvey’s Launches "Oracle": a Revolutionary Freeze-Dried, Highly Nutritious and Protein-Rich Line of Complete Foods for Dogs and Cats
2. Revolutionary techniques could help harness patients own immune cells to fight disease
3. Mount Sinai Grad Student, 25, Named to Forbes ’30 Under 30’ In Science and Healthcare for ‘Revolutionary New Ideas’
4. Brand id¦Strategic Partners Launches Revolutionary Personal Branding Success Program for Women
5. U of T Researchers uncover major source of evolutionary differences among species
6. Naturel Collagen Canada Unveils C RUM, the Newest Addition to the Revolutionary Natural Collagen Skin Care Product Line
7. Human Intellect Backsliding From Lack of Evolutionary Pressure: Study
8. Evolutionary information improves discovery of mutations associated with diseases
9. Vygone Presents a Revolutionary Electro Waveform Device to Help Treat Molluscum Contagiosum Lesions
10. A Revolutionary Dietary Paradigm: New Cookbook Features A SOS-free (Salt, Oil, Sugar ) Diet That Delivers the Optimal Food Plan for Renewing Health
11. Scientists at the Institute of Molecular Biology identify key event for sex determination
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... 2016 , ... David J. Dykeman , Ginger Pigott , and ... speak at DeviceTalks West, Dec. 12, 2016, at the Fairmont Newport Beach in California. ... firm’s global Life Sciences & Medical Technology Group have been featured speakers at every ...
(Date:12/8/2016)... Tampa, Fla (PRWEB) , ... December 08, 2016 ... ... offering smarter modes of access for customers and employees that are both engaging ... ChangeGear 7 with Service Smart Technology, the software company revealed today its plans ...
(Date:12/8/2016)... ... 2016 , ... Catalent Pharma Solutions, the leading global provider ... products, today announced that it had joined the Pharmaceutical Supply Chain Initiative (PSCI). ... unite pharmaceutical and healthcare companies that share a vision of better, social, environmental ...
(Date:12/8/2016)... ... December 08, 2016 , ... STAT courier is pleased ... a convenient service for Texas, they are expanding their presence in Dallas. One of ... spree that will bring new jobs to the Dallas and Forth Worth market. STAT ...
(Date:12/8/2016)... ... December 08, 2016 , ... Today’s patients are encouraged to ... mind, SIGVARIS has created a new line of anti-embolism stockings to help prevent ... the benefits of graduated compression when transitioning from recovery to early rehabilitation. , ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... AMSTERDAM , December 8, 2016 Information ... TM metrics in Scopus , the world,s largest ... free access to comprehensive metrics for journals from over 5,000 publishers. ... publish, which journals to subscribe to and when to adjust a ... , , ...
(Date:12/8/2016)... 2016 According to the research report, ... is expected to be worth US$9.7 bn by the ... Between the forecast years of 2016 and 2024, the global ... The leading players operating in the global diabetes injection pens ... plc., Biocon Ltd., and Sanofi S.A. Transparency Market Research reports ...
(Date:12/8/2016)... 2016 According to a new market research report ... Therapeutic (Pain, Insulin)), End Use (Sports, Fitness, RPM), Type (Smart watch, Patch), ... global market, in terms of value, is projected to reach 12.14 Billion ... 18.0% during the forecast period. Continue Reading ... ...
Breaking Medicine Technology: