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How bacteria talk to each other and our cells
Date:11/6/2012

ame type produced by Pseudomonas aeruginosa, a tough bacterium that causes illnesses in places like the lungs, intestines, and eyes. With the help of mass spectrometry, they have been able to see which proteins bind AHL.

"We have proof that physical contact between bacteria and epithelial cells is not always required; the influence can happen at a distance," Vikstrm says.

The team's discovery can open the door to new strategies for treatment where antibiotics cannot help. One possibility is designing molecules that bind to the receptor and block the signal path for the bacteria something like putting a stick in a lock so the key won't go in. It's a strategy that could work with cystic fibrosis, for example, an illness where sticky mucus made of bacterial biofilm and large amounts of white blood cells is formed in the airways.


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Contact: Elena Vikstrm
elena.vikstrom@liu.se
46-010-103-2054
Linkping University
Source:Eurekalert

Page: 1 2

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