Navigation Links
Hot on the TRAIL of graft vs. host disease
Date:5/15/2013

For patients with leukemia and other hematological malignancies, transplantation of hematopoietic stem cells (HSCT) can be a powerfully effective therapy. In addition to the desirable anti-tumor effect, transplanted cells can also attack the host tissue, resulting in graft-versus-host disease (GVHD). In this issue of the Journal of Clinical Investigation, Arnab Ghosh and colleagues at Memorial Sloan-Kettering Cancer Center found that expression of a protein that causes cell death, TRAIL, in transplanted cells was critical for an effective anti-tumor response. Immune cells engineered to express higher levels of TRAIL killed the cells that cause GVHD and increased anti-tumor activity. In an accompanying commentary, Nelson Chao suggests that new therapeutics may take advantage of TRAIL-expressing cells to promote an anti-tumor response without putting patients at risk for GVHD.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. Pan American Express Selects FleetLocate’s Rich Data Trailer Tracking Solution to Increase Visibility and Efficiencies of its Fleet of Dry Vans
2. The Truck Accident Victims’ Guide By Block O’Toole & Murphy, LLP: Protecting Yourself After A Collision With A Tractor-Trailer
3. Luxe Travel Trail Blazes with the Rise of the Virtual Agency
4. Save the Putnam Trail Announces Campaign Song
5. Autism Speaks trailblazer study -- Blocking cell distress signals can ease autism symptoms
6. Facebook Likes Leave a Personal Trail, Study Warns
7. French women trailing behind their European neighbors when it comes to sport and exercise
8. On the trail of mucus-eaters in the gut
9. Prescription Painkillers Trail Only Marijuana in Abuse Rates, Report Shows
10. Young researcher on the trail of herbal snakebite antidote
11. Medtronic Infuse Bone Graft Failure Allegation Lawsuits Information Bank for Consumers Now Available through Resource4thePeople
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2017)... , ... September 19, 2017 , ... Premiere Long Island ... Sami, was recently named one of the best dentists in America under age 40 ... dental professionals nationwide. Every fall, the magazine features the best 40 dentists under the ...
(Date:9/19/2017)... , ... September 19, 2017 , ... ... Inc. 5000 , the most prestigious ranking of the nation's fastest-growing private companies. ... American economy’s most dynamic segment— its independent small and midsized businesses. Endo-Systems is ...
(Date:9/18/2017)... ... ... set of dissolving transitions created for use within Final Cut Pro X . ... without the use of keyframes. Choose to bleed away darks and lights to ... to gradually dissolve away the light in a scene to reveal the following scene. ...
(Date:9/18/2017)... ... 18, 2017 , ... Cosmetic Town, an online plastic surgery and information community, ... of Cosmetic Tow, “Our forum section is an interactive, and popular, section of the ... members thinking about having cosmetic surgery. The interaction and sharing among our forum ...
(Date:9/18/2017)... ... September 18, 2017 , ... In the age of digital media, limiting ... distractions are readily available and a convenient way to soothe fussy children. , According ... make the switch to sensory development toys completely. , The study, entitled “Is handheld ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)...  Eli Lilly and Company (NYSE: ... to more efficiently focus resources on developing new ... workforce reductions, including those from a U.S. voluntary ... 3,500 positions. With the streamlining ... approximately $500 million that will begin to be ...
(Date:9/7/2017)... , Sept. 7, 2017  Zimmer Biomet Holdings, Inc. ... healthcare, today announced that it will be participating in ... Conference at the Grand Hyatt hotel in New York.  ... at 11:40 a.m. Eastern Time. A live ... Biomet,s Investor Relations website at http://investor.zimmerbiomet.com .   ...
(Date:9/6/2017)... , Sept. 6, 2017   PDI , a ... it will host an educational session focused on the ... infection (CLABSI) prevention at the 2017 Annual Scientific Meeting ... will take place at the Phoenix ... from Sept. 16-19, will also feature PDI,s ...
Breaking Medicine Technology: