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Hospital for special surgery physician-scientists share advances in rheumatology research
Date:11/5/2011

e program's patients are motivated to better control their cardiovascular health by maintaining healthy diet and exercise regimes. However, while there was a significant improvement in diet and exercise habits, the findings do not show a significant improvement in clinical parameters such as high blood pressure, body-mass index, or cholesterol profile at one-year follow-up. "We're encouraged that these patients are working hard to improve their cardiovascular health, and it is possible that they will have improved results after the study has reached the end of its third year," said senior author Doruk Erkan, M.D. "These results demonstrate just how difficult it is for lupus patients to improve their cardiovascular disease risk factors that would be relatively easier to achieve in most other individuals."

Tweaking Withdrawal of Rheumatoid Arthritis Medications Before Surgery May Reduce Disease Flares (2224)

Tuesday, November 8, 2011: 9:00 AM-6:00 PM; Room: Poster Hall

To minimize infections, doctors stop giving anti-TNF medications before surgery. These medications are powerful immunosuppressants and effectively control disease activity in RA patients. However, it is not known how long anti-TNFs should be held prior to surgery to ensure the best outcomes in patients. Stopping them too early may put these patients at risk for RA flares, which may complicate recovery. This study found no increased risk of infections in RA patients taking anti-TNF medications compared with those not on these medications, and a trend toward more postoperative flares in the anti-TNF patients. Different anti-TNFs were held seemingly arbitrarily, with no correlation to half-life. Rheumatologist Lisa Mandl, M.D., senior author of the study, said more evidence-based studies are needed to determine optimal timing of pre-operative use of these medications.

Stress Triggers Disease Flares in Patients with Vasculitis (2371)

Tuesday, November 8, 201
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Contact: Phyllis Fisher
phyllis.fisher@gmail.com
212-606-1197
Hospital for Special Surgery
Source:Eurekalert

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