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Hospital for Special Surgery scientists share advances in lupus and related conditions
Date:11/7/2010

ive approach to design and conduct large-scale clinical trials involving people who have APS," said Doruk Erkan, M.D., clinical co-director of the Mary Kirkland Center for Lupus Care at Hospital for Special Surgery. "At this summit, we hope to stimulate dialogue about this condition and formulate a solid research question from which to generate future clinical trials that are feasible, interesting and relevant."


Study Sheds Light on Aromatase Inhibitor Joint Pain Syndrome (898)
Tuesday, Nov. 9, 9 a.m. 11 a.m., Halls B1 & B2

Breast cancer patients are more likely to have joint pain from taking aromatase inhibitors (AIs) if they have advanced stage cancer, according to a new study that is one of the first to identify factors that increase the likelihood that a patient will experience joint pain from AI therapy. AIs, the standard of care for post-menopausal breast cancer, may cause debilitating joint pain, mainly in hands and wrists. "Patients complain bitterly about this pain that they get in their hands after starting these medications," said Lisa Mandl, M.D., rheumatologist at Hospital for Special Surgery, who was involved with the study. "It is so bad that sometimes patients stop taking AIs, even though we know the drugs are literally life-savingthey decrease the risk of dying from breast cancer."


Link Between Nervous System and Immune System Found to Impact Inflammation in Lupus (866)
Tuesday, Nov. 9, 9 a.m. 11 a.m., Halls B1 & B2

Many people with the autoimmune disease lupus believe that their condition worsens during stressful situations. Researchers have found that a pathway that connects the nervous system and immune system may influence the immune response to molecules involved in tissue injury and inflammation in complications of lupus, including kidney disease. "It's exciting that the link between the nervous system and the immune system may be used to decrease inflammation in organs that
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Contact: Phyllis Fisher
phyllis.fisher@gmail.com
212-606-1197
Hospital for Special Surgery
Source:Eurekalert

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