Navigation Links
Hospital-diagnosed maternal infections linked to increased autism risk
Date:12/23/2013

Hospital-diagnosed maternal bacterial infections during pregnancy were associated with an increased risk of autism spectrum disorders in children, according to a Kaiser Permanente study published Dec. 23 in the Journal of Autism and Developmental Disorders.

The research contributes new evidence to a body of scientific literature on the role of infection in autism risk and points to areas for further examination.

The study included 407 children with autism and 2,075 matched children who did not have autism. The study included infants born between January 1995 and June 1999 who remained members of the Kaiser Permanente health plan for at least two years following birth.

"Though infections in pregnant women are fairly common, in this study most were not associated with an increased risk of autism," said Lisa A. Croen, PhD, research scientist with the Kaiser Permanente Division of Research and senior author of the study. "Only bacterial infections diagnosed in the hospital were associated with an increased risk."

"Infections diagnosed in a hospital setting were more common among mothers of children who developed an ASD compared with mothers of children who did not develop an ASD," Croen further explained.

Women with bacterial infections diagnosed during a hospitalization (including of the genitals, urinary tract and amniotic fluid) had a 58 percent greater risk of having a child with an ASD. While not very common in any of the mothers studied (1.5 percent of mothers of a child with ASD vs. 0.5 percent of mothers of a child without ASD), infections diagnosed during a hospitalization in the second trimester were associated with children having more than a three-fold increased risk of developing ASD.

"Infections diagnosed in an inpatient setting may represent more severe infections, and these were associated with increased risk of ASD," said Ousseny Zerbo, PhD, research fellow with the Kaiser Permanente Division of Research and the study's lead author.

While the mechanism for how maternal infections may influence autism risk has not been firmly established, Zerbo said animal tests have shown that immune-system responses to infections during pregnancy may influence the neurological development of the fetus.

"Our findings indicate that although most infections during pregnancy were not associated with autism in the child, there appears to be some increased risk for autism," Zerbo said. "It would be prudent for pregnant women to contact their doctor if they suspect an infection."


'/>"/>

Contact: Joshua Weisz
jweisz@golinharris.com
202-664-9810
Kaiser Permanente
Source:Eurekalert

Related medicine news :

1. Partnerships at Base of Tanzania’s Maternal Health and Early Child Care Text Messaging Service Successful First Year
2. Scaling up: Ecuadorian Ministry of Health mobilizes resources to improve maternal and newborn care
3. Miriam Hospital researcher awarded $2.9 million NIH grant to study impact of maternal smoking
4. How are children affected by maternal anxiety and depression?
5. Maternal smoking may impair infant immunity, causing a broad range of infections
6. Maternal and Family Health Services Receives Grant from Robert Y. Moffat Family Charitable Trust for Kiosk Prenatal Education Module
7. More Babies are Oversized as Maternal Obesity Rate Rises, Lancet Report Says
8. LA BioMed researchers find maternal smoking linked to asthma in the third generation
9. Major awards for innovative solutions to prevent infant/maternal deaths
10. Doctors Launch New Website to Support Popular iTunes App babyQ, Help Pregnant Women Worldwide Improve Maternal and Fetal Health
11. Sun Buick GMC Sponsors Hole-In-One Contest For Maternal and Family Health Services Golf Tournament
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/31/2016)... ... , ... The successful implementation of “lean manufacturing” in various fields has inspired ... different challenges compared to manufacturing environments. , In order to provide a way ... developed the Lean Lab Checklist . This checklist will help users gain an ...
(Date:5/31/2016)... ... May 31, 2016 , ... WaterField Designs, an innovative leader ... the waxed-canvas and leather Duo Dopp Kit , the ideal gift upgrade for ... nylon, the Duo is smartly designed for Dad’s grooming routine. Two compartments ...
(Date:5/31/2016)... , ... May 31, 2016 , ... The Orthopaedic Research ... committee members: , David G. Lewallen, MD, began his term as president in ... Michael L. Parks, MD, is OREF’s new president-elect. Richard F. Kyle, MD, will serve ...
(Date:5/31/2016)... Clearwater, FL (PRWEB) , ... May 31, 2016 , ... ... for its innovative herbal energy pouches, on World No Tobacco Day . ... in select retail locations later on this summer. , The new flavor is ...
(Date:5/31/2016)... ... May 31, 2016 , ... Dr. Charles A. Ditta attained his Doctor ... in the class of 1986, where he graduated in the top ten percentile of ... in Livingston since 1989. He has been a member in good standing for thirty ...
Breaking Medicine News(10 mins):
(Date:5/30/2016)... , May 30, 2016 Eye ... parents of premature babies to seek an eye examination ... blinding condition     Moorfields Eye Hospital ... in London , has identified premature babies as ... problems, because of their particular vulnerability to retinopathy of prematurity (ROP). ...
(Date:5/27/2016)... According to the 2016 report, ... ambulatory blood pressure monitoring system market growth. With aging, ... to respond to different pressure rates, leading to hypertension ... various cardiovascular disorders such as heart failure, stroke, coronary ... growing in prevalence each year. WHO estimates that 17 ...
(Date:5/27/2016)... , May 27, 2016 Amarantus BioScience ... on developing products for Regenerative Medicine, Neurology and Orphan Diseases, today ... be presenting at two upcoming investor conferences: SeeThru ... Third Avenue, New York City , NY ... Marcum MicroCap Conference   Where: Grand Hyatt ...
Breaking Medicine Technology: