Navigation Links
Hormones after breast cancer: Not fuel for the fire after all?
Date:7/23/2014

A new study supports a growing body of research suggesting a safe and effective role for natural steroid hormones in treating postmenopausal breast cancer, with fewer detrimental side effects and improved health profile than with standard anti-hormone therapies. The study will be published in final format today in the open-access journal Reproductive Biology and Endocrinology.

Breast cancer is the most frequently diagnosed cancer in women in the United States. Approximately 70% of breast cancers are diagnosed in postmenopausal women. Major clinical trials and experimental studies showed that a class of anti-estrogen drugs called aromatase inhibitors (AIs) is effective against postmenopausal breast cancer. Yet despite their effectiveness in reducing tumor recurrence, aromatase inhibitors have adverse effects on the cardiovascular system and increase osteoporosis and bone fractures, which may explain their lack of overall survival improvement versus the older treatment, tamoxifen. These effects, together with undesirable side effects such as incontinence and bone and joint pain, cause many women to discontinue using AIs. Alternatives are needed.

In their study, researchers at the Center of Excellence in Cancer Research at the Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, set out to explore a radical and counterintuitive hypothesis: Could an optimal choice of hormones lead to improved survival factors and quality of life, enough to outweigh any negative effect on tumor recurrence? Radicalbecause current standard of practice considers hormone treatment of any type absolutely contraindicated following hormone-receptor-positive breast cancer. Counterintuitive because estrogen-blocking aromatase inhibitors, a nearly opposite treatment, are the current adjuvant treatment for women after hormone-sensitive breast cancer.

Results from this study in a mouse model suggest the answer to their question is "
'/>"/>

Contact: Elaine Lissner
pr@parsemusfoundation.org
415-839-6304
Parsemus Foundation
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Restoring thyroid hormones in heart may prevent heart disease from diabetes
2. Yoga regulates stress hormones and improves quality of life for women with breast cancer undergoing
3. Top 19 Foods That Repair Hormones Reveals Super Nutrients to Re-balance Fat Loss Hormones Released by Health News Wires
4. “14 Natural Ways To Balance Hormones”, A New Article on V-Kool.com, Teaches People How to Balance Their Hormones Naturally - V-kool
5. Aerobic fitness and hormones predict recognition memory in young adults
6. No hot flashes? Then dont count on hormones to improve quality of life
7. Hormones, Health, Wellness & You Seminar Will Take Place on November 14
8. Hormones, Health, Wellness & You Seminar Will Take Place on September 24
9. How to Lose Weight after Having a Baby
10. “Lose That Baby Weight Program” Teaches People How to Balance Their Female Hormones – Health Review Center
11. Hormones for Digestion and Weight Loss Article and Video Published by BetterDigestion.org
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... The report “Nintedanib (Colorectal Cancer) – ... the current treatment landscape, unmet needs, current pipeline ... Stivarga is a drug which is used in ... Ingelheim is developing nintedanib (BIBF-1120), an orally available ... in the US, Europe, and Japan. The drug ...
(Date:12/25/2014)... Dylan Queen, a famous online company supplying women’s special ... prom dresses, most of which are priced under $200. ... the promotion is valid until Jan. 22, 2015; the ... market. , The prom dresses in this new collection ... strapless, empire strapless chiffon, one shoulder, floor-length, V-neck beading, ...
(Date:12/25/2014)... FL (PRWEB) December 25, 2014 When head ... find themselves in a frenzy to get rid of it ... But families in Coral Gables now have the solution right ... second salon clinic location, Lice Troopers provides full spectrum head ... the Coral Gable area, including Sunset, Key Biscayne, Brickell, Coconut ...
(Date:12/25/2014)... -- Among early stage breast cancer patients who undergo ... percent will eventually develop leukemia as a result of ... comes from a review of more than 20,000 breast ... suggests that the risk for developing treatment-related leukemia, though ... "The frequency of bone marrow cancers such as ...
(Date:12/25/2014)... 25, 2014 Plugin creators from Pixel ... A fully customizable business presentation tool made specifically for ... ProFire 5k business tool, users can now display their ... of Pixel Film Studios. “ProFire 5k gives users a ... add professionalism to a presentation” , Pixel Film Studios ...
Breaking Medicine News(10 mins):Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 3Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2
... of biology in the School of Science at Indiana ... eye and vision research organization in the world for ... blindness caused by macular degeneration, retinitis pigmentosa and other ... Research in Vision and Ophthalmology (ARVO) will present Meyer ...
... researchers have shown for the first time how peppermint ... to 20% of the population. In a paper ... , researchers from the University,s Nerve-Gut Research Laboratory explain ... soothing inflammatory pain in the gastrointestinal tract. Dr ...
... shows how inflammation can help cause cancer. Chronic inflammation ... inflammatory bowel disease is associated with up to 25 ... the Ohio State University Comprehensive Cancer Center Arthur ... Institute (OSUCCC James) found that inflammation stimulates a ...
... more effective than cutting calories for individuals who want to ... UT Southwestern Medical Center researchers. "What this study tells ... to reduce the amount of fat in your liver, you ... assistant professor of internal medicine at UT Southwestern and the ...
... , MONDAY, April 18 (HealthDay News) -- Patients with do-not-resuscitate ... after surgery, even after non-emergency procedures, a new study finds. ... used to revive someone who is clinically unresponsive and lacks ... and in the August print issue of the journal ...
... , MONDAY, April 18 (HealthDay News) -- Infection ... of many college students -- and little exposure to sunlight ... sclerosis, a new study suggests. "MS is more common ... lead researcher, Dr. George C. Ebers, of the University of ...
Cached Medicine News:Health News:IUPUI faculty member to receive national innovative vision research award 2Health News:Peppermint earns respect in mainstream medicine 2Health News:Study shows how inflammation can lead to cancer 2Health News:Limiting carbs, not calories, reduces liver fat faster, UT Southwestern researchers find 2Health News:People With DNR Orders More Apt to Die After Any Surgery 2Health News:Can Common Virus, Lack of Sunlight Boost MS Risk? 2
(Date:12/24/2014)... LONDON , December 24, 2014 /PRNewswire/ ... expected to grow at an average rate of 8.1%. ... and volume. Hip, knee and spine surgeries are the ... emerging economies they have a lower penetration. Increased number ... use of composites. Non-metallic orthopedic devices have gained popularity ...
(Date:12/24/2014)... Dec. 23, 2014  Advanced Medical Isotope Corporation ... primarily in the development of brachytherapy devices and ... announced that it has filed a de ... Administration ("FDA") for marketing clearance for its patented ... the U.S. Food, Drug and Cosmetic Act (the ...
(Date:12/24/2014)... , Dec. 23, 2014   Synageva BioPharma ... biopharmaceutical company developing therapeutic products for rare disorders, ... (EMA) of the Marketing Authorization Application (MAA) for ... granted the company,s request for accelerated assessment, which ... review time.   The MAA, and ...
Breaking Medicine Technology:Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3
... , GREENVILLE, S.C. , ... provide an online, real-time webcast and rebroadcast of its conference ... for the first quarter of fiscal 2010, which will be released ... The live broadcast of Span-America,s conference call will be available ...
... , , ... ERES ), a leading provider of centralized services to the ... ERT Knowledge Series of educational papers, written by ERT experts. ... trials today and further establishes ERT as an experienced and ...
Cached Medicine Technology:Span-America Announces First Quarter Conference Call On The Internet 2ERT Demonstrates Patient Safety Expertise in Clinical Trials with New Knowledge Series of Papers 2ERT Demonstrates Patient Safety Expertise in Clinical Trials with New Knowledge Series of Papers 3ERT Demonstrates Patient Safety Expertise in Clinical Trials with New Knowledge Series of Papers 4ERT Demonstrates Patient Safety Expertise in Clinical Trials with New Knowledge Series of Papers 5
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: