Navigation Links
Hormones Boost Frequency of Women's Migraine With Aura

Mouse study finds 2 genes likely behind spread of depression with these headaches

MONDAY, Dec. 22 (HealthDay News) -- In women, hormones increase the frequency of an inherited form of severe migraine accompanied by visual disturbances called auras, according to a Massachusetts General Hospital study.

Like other types of migraine, familial hemiplegic migraine affects women more than men. Most cases of familial hemiplegic migraine are caused by mutations in the CACNA1A gene. However, it hasn't been clear whether these mutations lead to spreading depression -- the event in the brain that suppresses nerve cell activity and has been linked to non-genetic forms of migraine with aura, according to background information in the study.

The study authors found that mice expressing either one or two different CACNA1A mutations that lead to familial hemiplegic migraine in humans had increased susceptibility to spreading depression. The mutation associated with more severe familial hemiplegic migraine caused a greater increase in susceptibility to spreading depression than the mutation linked to a milder form of familial hemiplegic migraine.

Female mice were more likely to have spreading depression than male mice, but this difference was reversed if the female mice had their ovaries removed and then partially restored by replacement of the hormone estrogen.

The researchers concluded that both genetic and hormonal factors affect a person's susceptibility to migraines with aura.

The study was published in the current issue of the Journal of Clinical Investigation.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about migraine headaches.

-- Robert Preidt

SOURCE: Journal of Clinical Investigation, news release, Dec. 22, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Fat-Sensing Hormones Might Fight Obesity
2. Hormones May Be to Blame for Womens Cavity Rates
3. Breast Cancer Action Targets Yoplait in Think Before You Pink Campaign; Calls for Yogurt Without Artificial Hormones
4. Age alone should not be used to determine whether to treat prostate cancer with hormones
5. Menopause: Hot Flashes Can Be Reduced 90% without Hormones
6. Patients, Doctors, Pharmacists Praise Bipartisan House Resolution on Compounded Hormones Containing Estriol
7. ENDO 08: Latest news on hormones, steroids, obesity, diabetes and more
8. Heart Hormones Beat Back Cancers in Mice
9. Sex Hormones Dont Seem to Affect Prostate Cancer Risk
10. FDA Asserts New Policy to Restrict Womens Access to Bioidentical Hormones
11. Experts call for better research into link between womens hormones and mood disorders
Post Your Comments:
Related Image:
Hormones Boost Frequency of Women's Migraine With Aura
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now ... of Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Final Cut Pro X users can now reveal the media of their split ...
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... ambulance transport experience for the millions of people who require these medical transport ... taxi industry through the use of technology. Now, SmartEMS has put forth an ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... On June ... sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, ... of the city’s history as home to some of the world’s leading providers of ...
(Date:6/26/2016)... ... ... legally blind and certified personal trainer is helping to develop a weight loss fitness plan ... fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs ... College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. ... treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
(Date:6/23/2016)... -- Research and Markets has announced the ... (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, ... Global Forecast to 2021" report to their offering. ... pharmaceutical excipients market is projected to reach USD 8.1 ... the forecast period 2016 to 2021. ...
Breaking Medicine Technology: