Navigation Links
Hormone therapy may confer more aggressive properties to prostate tumors
Date:6/10/2009

Hormone therapy is often given to patients with advanced prostate cancer. While it is true that the treatment prevents growth of the tumour, it also changes its properties. Some of these changes may result in the tumour becoming more aggressive and more liable to form metastases. This is one of the conclusion of a thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden.

Hormone therapy has serious side effects and is therefore used only when the tumour has grown too large to be treated in any other way, or when the tumour has spread and formed metastases. The hormone that is given causes the natural production of male sex hormone to fall, and the tumour stops growing. Pain also usually decreases.

"Our results suggest that the tumour properties change following hormone therapy such that the tumours at a later stage can continue to grow and spread in the body. For this reason, it is probably necessary to supplement the hormone therapy in order to compensate for these changes", says pharmacist Karin Jennbacken, author of the thesis.

The results show that patients who have been given hormone therapy have higher levels of the proteins that enable the cancer cells to move through the body and attach to other organs. One of these proteins is known as "N-cadherin", and this protein is present in higher levels in patients who have been given hormone therapy.

"We don't have any good treatment alternatives in cases where the tumour returns after hormone therapy, and this means that it is particularly important to study how such tumours are controlled and how they behave. The properties that we have identified may become targets for new anti-metastatic drugs in advanced prostate cancer", says Karin Jennbacken.


'/>"/>

Contact: Elin Lindstrm Claessen
elin.lindstrom@sahlgrenska.gu.se
46-317-863-869
University of Gothenburg
Source:Eurekalert  

Page: 1

Related medicine news :

1. Pausing Hormone Therapy Doesnt Cut Mammogram Recalls
2. Fighting "Brain Fog": How the Right Hormones Can Improve Mental Sharpness for Women
3. What You Need to Know in Your 40s to Have a Healthy Menopause -- Without Hormone Replacement Therapy
4. Action of ghrelin hormone increases appetite and favors accumulation of abdominal fat
5. A stronger backbone: DHEA hormone replacement increases bone density in older women
6. Womens International Pharmacy Offers Free Educational Information About Bioidentical Hormone Replacement Therapy
7. Test for hormones in blood not reflective of hormones in breast tissue; breast cancer risk
8. Hormone therapy offers potential protective effect against colon cancer in older women
9. Female hormone cycle affects knee joints
10. IROs Help Determine Medical Necessity of Growth Hormone Therapy
11. A potential new target for treatment of hormone refractory prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hormone therapy may confer more aggressive properties to prostate tumors
(Date:7/22/2014)... (WASHINGTON, July 22, 2014) The American Society ... of the University of California Los Angeles with ... research in iron homeostasis, including the discovery of the ... iron metabolism. This award, named after the Nobel Prize ... recognizes pioneering research achievements in hematology that have represented ...
(Date:7/22/2014)... you eat pretty much everything you put on your ... study shows that the average adult eats 92% of whatever ... "If you put it on your plate, it,s going ... forthcoming book, Slim by Design, Professor of Marketing and Director ... co-author Katherine Abowd Johnson analyzed 1179 diners and concluded that ...
(Date:7/22/2014)... American Society of Hematology (ASH) will present the Society,s ... Lifetime Achievement in Hematology, to Kanti R. Rai, MD, ... of Medicine for his 50-year career combining landmark clinical ... exceptional patient care. , The Wallace H. Coulter ... an individual who has been a vital contributor to ...
(Date:7/22/2014)... 22, 2014 SIMpalm, a ... payment app for Forte Payment System. Forte Mobile Payment ... payments on iPhone, iPod and iPad. The app ... recently updated by SIMpalm. This update was for iOS ... supported on iOS 4.3 and is available to download ...
(Date:7/22/2014)... 6th Latin American Conference on Lung Cancer (LALCA 2014) ... Lima, Peru. , Lung Cancer is still the leading ... worldwide. Building on the success of the previous conferences ... speakers will discuss the science and advances in the ... worldwide and Latin America in particular. , With tobacco ...
Breaking Medicine News(10 mins):Health News:Tomas Ganz, M.D., Ph.D., to present 2014 ASH E. Donnall Thomas Lecture 2Health News:Tomas Ganz, M.D., Ph.D., to present 2014 ASH E. Donnall Thomas Lecture 3Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 2Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 3Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 4Health News:SIMpalm Launched Updated Forte Mobile Payment App on iPhone and iPad for Its Client 2Health News:SIMpalm Launched Updated Forte Mobile Payment App on iPhone and iPad for Its Client 3
... Plan, Inc.,a leading provider of Medicare Advantage health plans ... expanded into the,state of Oklahoma. This comes on the ... Maine., Highlights of these plans include $0 premiums ... benefits, and an ever-expanding,provider and hospital network., "We,ve ...
... actively cleans its most selective filter to keep it from ... Medicine in St. Louis reveal in a new study. ... make kidneys more vulnerable to dysfunction and disease. , ... things on the filter that can damage it," says senior ...
... for, Secure Remote Access to Windows Terminal Servers from ... ... N.J., Jan. 29 Ericom Software, a leader in,Application ... Health Unit, a major Canadian community health agency, has,evaluated, ...
... February is National,Children,s Dental Health Month and starting ... will receive free dental services ranging,from dental fillings ... of the American Dental Association,s sixth annual "Give ... to disadvantaged children who,don,t have access to dental ...
... Ray Society to add more journals and images to ... the open access publisher of peer-reviewed biomedical research has ... the GoldMiner collection. The collection now numbers over 170,000 ... search for radiology images by quickly matching search criteria ...
... CHAPEL HILL, N.C., Jan. 29 In ... blindside an unwary,pharmaceutical company and nullify product ... high-impact analyses on competitors,products and operations, a ... emerging market opportunities as well as warn,them ...
Cached Medicine News:Health News:Expanded Options for Medicare Beneficiaries in Oklahoma 2Health News:Breakdown of kidney's ability to clean its own filters likely causes disease 2Health News:Breakdown of kidney's ability to clean its own filters likely causes disease 3Health News:Major Community Health Organization Lowers TCO with Ericom's Alternative to Citrix 2Health News:Major Community Health Organization Lowers TCO with Ericom's Alternative to Citrix 3Health News:Michigan Dentists Giving Free Dental Care to Low-Income Children During Annual 'Give Kids a Smile' Program Starting February 1 2Health News:Michigan Dentists Giving Free Dental Care to Low-Income Children During Annual 'Give Kids a Smile' Program Starting February 1 3Health News:Building and Sustaining Impactful Competitive Intelligence Organizations for Pharma 2
(Date:7/22/2014)... NASHVILLE, Tenn. , July 22, 2014 ... will release second quarter 2014 financial results after the ... call and live Internet webcast will be held on ... to discuss the results. To participate in ... 253-237-1032 (for international callers).  A rebroadcast of the teleconference ...
(Date:7/22/2014)... 22, 2014  Decision Resources Group finds that the market ... will remain relatively stagnant at a value of around ... percutaneous coronary intervention (PCI) volumes are growing faster in ... as the United States and ... by the increase in penetration of PCI procedures relative to ...
(Date:7/22/2014)... Research and Markets  has announced the ... report to their offering. ... diagnose, monitor, and assess medical conditions, diseases, or infections ... for earlier and more targeted treatment. These tests are ... results. This kind of diagnostics provides early detection of ...
Breaking Medicine Technology:Cumberland Pharmaceuticals To Announce Second Quarter 2014 Financial Results On August 5, 2014 2The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 2The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 3Global IVD Market 2014-2018: Key Vendors are Abbott Laboratories, Johnson & Johnson, Roche Diagnostics and Siemens Healthcare 2Global IVD Market 2014-2018: Key Vendors are Abbott Laboratories, Johnson & Johnson, Roche Diagnostics and Siemens Healthcare 3
... CALGARY, Alberta, July 13, 2011 Fero Industries, ... report that Merck S.A. de C.V. has successfully ... points-of-sale to over 2,500 outlets and pharmacy chains. ... well-known retailers including WalMart Supercenters, Superama, Farmacias del ...
... Schein, Inc. (NASDAQ: HSIC ), the largest provider ... the Henry Schein Cares Foundation, Inc., announced today a contribution ... help provide health care to those who have been affected ... earthquake in New Zealand, and tornadoes in the United States. ...
Cached Medicine Technology:Fero Industries Expands SucanonĀ® Distribution in Mexico 2Fero Industries Expands SucanonĀ® Distribution in Mexico 3Henry Schein Cares Foundation and Henry Schein Cares Contribute More Than $375,000 in Financial and Product Donations for Disaster Relief Efforts on Three Continents 2Henry Schein Cares Foundation and Henry Schein Cares Contribute More Than $375,000 in Financial and Product Donations for Disaster Relief Efforts on Three Continents 3
Y shape rotator tip. Shaft angled 7 mm from tip to bend. Round knurled handle with polished finish. Most popular size or model....
1.0 mm long 90 degree angled tip with black ebonized shaft. Titanium handle with position reference indicator. Shaft length 52 mm, handle length 100 mm....
Delicate pick with 90 degree hook tip. 20 gauge shaft with balanced titanium handle. Dark finish for reduced glare....
0.5 mm angled tip. Round knurled handle with dull finish. Tip angle: 110 degrees. Most popular size or model....
Medicine Products: