Navigation Links
Hormone therapy for prostate cancer does not appear to increase cardiac deaths
Date:12/10/2008

rent study found that men with localized prostate cancer who received GnRH agonist therapy had a greater risk of developing diabetes or cardiovascular disease than patients not receiving hormonal treatment. To specifically investigate the relationship between GnRH agonist therapy and death from cardiovascular disease, the current study analyzed data from a 1987-92 clinical trial in which almost 1,000 patients were treated for locally advanced prostate cancer with either the GnRH agonist goserelin plus radiation therapy or radiation therapy alone.

During the decade following completion of the clinical trial, more than half the participants died from various causes. Of the 574 deaths, 117 were from cardiovascular disease, but whether or not patients had received the GnRH agonist apparently had no effect on the risk of cardiovascular death. Instead, it was established cardiac risk factors including heart disease or diabetes that existed prior to GnRH agonist treatment that appeared to increase the risk of dying from cardiovascular disease.

"The absence of an increase in cardiovascular mortality does not exclude the possibility that GnRH agonists increase non-cancer deaths through other mechanisms," Efstathiou stresses. "In addition to the increased risk for diabetes identified in the 2006 study, we know they can raise the risk of fractures and anemia both of which can reduce survival and can have adverse effects on weight gain, cholesterol levels, mood and sexual function.

"While our study supports the continued use of GnRH agonists in situations where the benefit for cancer control has been established typically the treatment of advanced or more aggressive prostate cancer clinicians should keep in mind the risks of diabetes and cardiovascular disease and help their patients adopt strategies to reduce those risks," he adds. "Further studies are needed to evaluate potential risks for men with earlier stage prostate cancer, for
'/>"/>

Contact: Katie Marquedant
kmarquedant@partners.org
617-726-0337
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Drop in breast cancer incidence linked to hormone use, not mammograms
2. Researchers develop long-lasting growth hormone
3. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
4. Less than one-third of women aware of landmark hormone therapy study, Stanford researcher finds
5. Most Women Unaware of Hormone Replacement Study
6. Survival data presented from phase II study of hormone-resistant prostate cancer patients
7. Hormone May Play Key Part in Creating Memories
8. Hormone Therapy for Prostate Cancer Linked to Heart Risks
9. Wyeth to Appeal Nevada Hormone Therapy Trial Verdict
10. New data on hormone therapy must lead to re-evaluation of official guidelines
11. From Hot Flashes to Breast Cancer: ZRT Labs Hormone Testing Catches On As Women Consider Safer, More Natural Options.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... -- Both drinking and getting drunk at an early ... high school students, a new study suggests. The ... who drink, could help expand alcohol-prevention efforts aimed at ... them from becoming binge drinkers, the researchers suggested. , ... use and progression to first heavy use as risk ...
(Date:9/23/2014)... Francisco, CA (PRWEB) September 23, 2014 Avid ... for original 1967 The Doors Eagle Auditorium Seattle concert posters. ... their album “Break On Through” that year. The Seattle Eagles ... to Hawley, “The Doors would return to Eagles Auditorium in ... July poster is not known and comes in three colors. ...
(Date:9/23/2014)... Grinnell Mutual seeks submissions from the ... Midwest. Working Together Making It Better will provide ... projects positively impacting their communities. , “So many ... communities a better places,” said Grinnell Mutual ... Baker. “Their leadership—as coaches, as volunteers, as mentors—help ...
(Date:9/23/2014)... 2014 (HealthDay News) -- Few children who ... behavioral therapy, and the rates vary six-fold across ... finds. Medication alone can manage symptoms for ... if they also receive behavioral therapy (psychotherapy), the ... data in more than 1,500 counties across the ...
(Date:9/23/2014)... recent Oregon survey about an exercise DVD that adds ... of elementary school students found it had a high ... offered clear advantages for overly sedentary educational programs. , ... by the Healthy Youth Program of the Linus Pauling ... , Brain Breaks leads children in 5-7 minute segments ...
Breaking Medicine News(10 mins):Health News:Younger Age at First Drink, Higher Odds for Problem Drinking: Study 2Health News:Younger Age at First Drink, Higher Odds for Problem Drinking: Study 3Health News:Grinnell Mutual Invites Submissions for Innovative, Collaborative Local Projects in Its Second Annual Working Together Making It Better Promotion 2Health News:Kids Taking ADHD Drugs Get Little Psychotherapy: Study 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 3
... 352,082 Australians who filled a prescription for asthma preventer medications ... June 2005, went on to use them regularly. , Most ... the next two years while 22% did so sporadically. , ... Australia and New Zealand (TSANZ) Conference which starts this Sunday ...
... IRIDEX,Corporation (Nasdaq: IRIX ) today announced that ... financial results after the market closes on,Thursday, April 10, ... a conference call with the investment community at 5:00 ... the results of the quarter and,other business developments., ...
... a Six Pack While Giving Back Through Fitness Fundraiser for St. ... Jude Children,s Research Hospital(R), ... will "feel the burn" as they crunch their abs for one,hour ... More than 200 local Lady of America, Ladies Workout,Express and Workout ...
... Sawyer Promoted; ... Bill McKee,s Role Expanded, MONTVALE, ... today announced the restructuring of its,senior management team to better ... increase efficiencies,across the global organization. Barr,s Chairman and Chief Executive,Officer, ...
... to Date, WASHINGTON, March 28 U.S.News ... 2009 edition of America,s Best,Graduate Schools, available at ... 2008. Examining more graduate programs than ever before,this ... the most,comprehensive guide to graduate schools across the ...
... March 28 Long-chain (seafood) omega-3,polyunsaturated fatty acids ... and eye health, according to recent research summarized ... Newsletter electronic publications.,Groundbreaking studies also show that omega-3s ... eye syndrome., The effect of fish oil ...
Cached Medicine News:Health News:4,000 Women Attempt New World Record at 2008 Lady of America/Ladies Workout Express Ab Crunch Challenge 2Health News:Barr Announces Reorganization of Senior Management, Business Functions 2Health News:Barr Announces Reorganization of Senior Management, Business Functions 3Health News:Barr Announces Reorganization of Senior Management, Business Functions 4Health News:Barr Announces Reorganization of Senior Management, Business Functions 5Health News:Barr Announces Reorganization of Senior Management, Business Functions 6Health News:Barr Announces Reorganization of Senior Management, Business Functions 7Health News:U.S.News & World Report Announces the 2009 Publication of America's Best Graduate Schools 2Health News:U.S.News & World Report Announces the 2009 Publication of America's Best Graduate Schools 3Health News:Omega-3 Fatty Acids Protect the Spinal Cord, Heart, Brain and Eyes 2
(Date:9/23/2014)... Ultrasound devices enable physicians to image ... diagnose diseases and also these devices help surgeons ... surgeries. This report studies the global ultrasound devices ... type, technologies, applications and the major geographic markets. ... product type has been segmented as: cart/trolley based ...
(Date:9/23/2014)... , Sept. 23, 2014 Nuclear ... by 2015. Radiopharmaceuticals/ Nuclear are drugs ... nuclear imaging field to diagnose and treat diseases. ... ailments, Increasing awareness for radiopharmaceuticals, and ready availability ... this market. Furthermore, increased public awareness and use ...
(Date:9/23/2014)... CAESAREA, Israel , Sept. 23, 2014 /PRNewswire/ ... of the Dario™ Diabetes Management Solution, today announced ... placement offering consisting of shares of preferred stock ... this financing.  After estimated offering expenses, LabStyle expects ... from this financing. LabStyle intends ...
Breaking Medicine Technology:Ultrasound Devices Market (By Product Type, By Technology and By Application - Obstetrics and Gynecology, Cardiovascular, Abdominal and Others) - Global Industry Analysis, Size, Share, Growth, Trends & Forecast, 2013 - 2019 2Ultrasound Devices Market (By Product Type, By Technology and By Application - Obstetrics and Gynecology, Cardiovascular, Abdominal and Others) - Global Industry Analysis, Size, Share, Growth, Trends & Forecast, 2013 - 2019 3Global Nuclear Medicine Market - Growth, Trends & Forecasts (2014-2019) 2LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 2LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 3LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 4LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 5
... Temporary, Transvenous Pacing Lead System Features an ... lubricated guide catheter. The system is designed ... The system is disposable, for temporary single ... of 7 days or less. The lead ...
Automated slide maker and stainer...
... The new ... an electromagnetic braking ... years of reliable ... whisper-quiet operation. The ...
The Schiller treadmill ergometer is designed for stress tests, sports medicine and cardiology. It is equipped and tested with the latest safety system and has been manufactured under the stringent qu...
Medicine Products: