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Hormone improves long-term recovery from stroke
Date:5/16/2011

positive effect of high IGF-I levels in the early phase after a stroke, while the scientists at the Sahlgrenska Academy have now demonstrated that the positive effects on recovery remain long after the stroke event.

"Our results may explain why patients who exercise more actively, with physiotherapy and physical exercise, demonstrate better recovery after a stroke. Unfortunately, we do not know how much our patients exercised after the stroke. This means that we need to carry out further studies in which we measure both the amount of physical activity and the levels of IGF-I, in order to understand the exact relationships better", David berg points out.

These results pave the way for further studies on whether drug treatments that raise IGF-I levels can improve long-term recovery after stroke. David berg believes that two avenues are open: either to treat with IGF-I, or to treat with the better known growth hormone (GH). This can stimulate the body's own production of IGF-I.

"Of course, these possibilities must be tested in carefully constructed clinical trials, so that we discover any undesired effects that must be considered. This is particularly true during the acute phase of a stroke, while treatment during the recovery phase is probably easier and has greater benefit", says David berg.


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Contact: David berg
david.aberg@medic.gu.se
46-031-342-8422
University of Gothenburg
Source:Eurekalert

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