Navigation Links
Hormone Therapy May Fight Resistant Prostate Cancer
Date:4/14/2010

Experimental treatment offers hope against cancer that returns after castration

WEDNESDAY, April 14 (HealthDay News) -- Preliminary research suggests that a new hormone treatment could be a weapon for doctors in the battle against a form of prostate cancer that's resistant to surgical removal of the testicles.

Only two of the three phases of research required for new drug treatments have been completed, however. At this point, it's not clear whether the treatment will go on to receive federal approval.

The hormone treatment, called MDV3100, is being tested as a treatment for a disease known as castration-resistant prostate cancer, according to a report on the research, published online April 14 in The Lancet.

Prostate tumors need testosterone to grow. One treatment involves castration, possibly with additional drug treatment, to combat the body's processing of testosterone.

Though the treatment kills some cancer cells, others remain alive but dormant, the researchers explained in a news release from the journal. And these cells can re-grow and survive without as much testosterone, thus becoming castration-resistant, they said.

For their study, Dr. Howard Scher of Memorial Sloan-Kettering Cancer Center in New York City and his colleagues tested the MDV3100 hormone treatment in 140 men in the United States with castration-resistant prostate cancer. The researchers gave varying doses, from 30 to 600 milligrams a day, to the men to find the maximum tolerable dose, which they determined to be 240 milligrams.

"We recorded encouraging anti-tumor activity with MDV3100 in patients with castration-resistant prostate cancer," both before and after chemotherapy, the researchers wrote in their report.

The researchers have begun a third phase of testing in which they will compare the hormone treatment to a placebo to see if it helps men with advanced prostate cancer live longer.

More information

For more about prostate cancer, visit the U.S. National Cancer Institute.



-- Randy Dotinga



SOURCE: The Lancet, news release, April 14, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Hormones Tied to Diabetes Might Also Influence Fertility
2. Anti-aging hormones: Little or no benefit and the risks are high
3. Demonstrated in vivo the transfer of maternal thyroid hormones to the fetus
4. Novel soy germ-based dietary supplement, SE5-OH containing natural S-Equol, examined for safety and influence on hormones in pre- and post-menopausal women
5. Promising hormone may help reduce malnutrition in gastric cancer patients
6. Hormone Replacement Might Relieve Arthritis
7. Hormone replacement in joint fluid has potential regenerative effect
8. Another perk of painkillers? Decreased hormone levels may reduce cancer risk
9. Metagenics Launches Estrovera™, an All-Natural, Clinically Demonstrated Alternative to Hormone Therapy for Relief of Hot Flashes and Other Menopausal Symptoms*
10. Thyroid hormone analogue for treating high cholesterol
11. Thyroid Hormone Analogue for Treating High Cholesterol
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... , ... June 24, 2016 , ... ... supporting the upcoming 2016 Miss Arizona pageant as its official Medspa Sponsor. Dr. ... Tempe, Mesa, and Chandler, Arizona. , Dr. Olson says the decision to ...
(Date:6/24/2016)... ... June 24, 2016 , ... To succeed under value-based payments, ... are unsure how to move forward, given the need to sustain current operations. ... tailored to an organization’s specific needs. , PYA Principal Martie Ross states, “Healthcare ...
(Date:6/24/2016)... ... June 24, 2016 , ... Today, InhaleLabs.com (Inhale) offilially launched ... medication by matching users with high quality water pipes within an ideal price range. ... , Inhale was founded by two brothers, Nick and Mike Hunter, who use medical ...
(Date:6/24/2016)... Austin, TX (PRWEB) , ... June 24, 2016 , ... ... laude graduate, joins Evans Dermatology in the South Lamar location as of July 13, ... Texas Southwestern Medical School. As a medical student, she regularly volunteered at the Agape ...
(Date:6/23/2016)... ... 2016 , ... An article published June 8 on AOL News ... neck cancer in individuals with unhealthy oral hygiene habits. The article goes on to ... had gum disease, brushed their teeth on a daily basis, wore dentures and if ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Dublin ... of the " Global Markets for Spectroscopy Equipment" ... This report focuses on the global ... including its applications in various applications. The report deals ... three main industries: pharmaceutical and biotechnology, food and beverage, ...
(Date:6/24/2016)... , June 24, 2016 Research ... World Market for Companion Diagnostic Tests" report to their ... Market for Companion Diagnostics The World Market ... and personalized medicine diagnostics. Market analysis in the report includes ... Test Market (In Vitro Diagnostic Kits) by Region (N. America, ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
Breaking Medicine Technology: