Navigation Links
Hormone Shows Potential as Diabetes Treatment in Mice
Date:4/25/2013

THURSDAY, April 25 (HealthDay News) -- A hormone that could lead to more effective diabetes treatment has been identified by researchers.

The hormone, called betatrophin, causes mice to produce insulin-secreting pancreatic beta cells at up to 30 times the normal rate. But it only produces insulin when the body needs it, according to the team at the Harvard Stem Cell Institute.

The researchers said their findings offer the potential for the natural regulation of insulin and a significant reduction in diabetes-related complications such as blindness and limb amputation.

The study is published in the April 25 online edition of the journal Cell and in its May 9 print issue.

Although the hormone shows promise in lab mice, much more work is needed before it could be considered as a treatment for diabetes in humans, the researchers noted. Results obtained in animal experiments often aren't attainable in trials with humans.

"If this could be used in people, it could eventually mean that instead of taking insulin injections three times a day, you might take an injection of this hormone once a week or once a month, or in the best case maybe even once a year," Doug Melton, co-director of the institute and co-chair of Harvard University's department of stem cell and regenerative biology, said in a university news release.

About 26 million Americans have type 2 diabetes, which causes people to slowly lose beta cells and the ability to produce sufficient amounts of insulin.

"Our idea here is relatively simple," Melton said. "We would provide this hormone, the type 2 diabetic will make more of their own insulin-producing cells, and this will slow down, if not stop, the progression of their diabetes. I've never seen any treatment that causes such an enormous leap in beta cell replication."

Along with its potential for treating type 2 diabetes, betatrophin might also have a role in treating type 1 diabetes, Melton said.

Unlike type 2 diabetes, which is associated with being overweight and sedentary, type 1 diabetes is an autoimmune disease that occurs most often in children and young adults.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes.

-- Robert Preidt

SOURCE: Harvard University, news release, April 25, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hormones For Weight Control Article And Video Published by BetterDigestion.org
2. Researchers identify and block protein that interferes with appetite-suppressing hormone
3. Intermittent Hormone Treatment for Prostate Cancer Not the Best
4. Study Suggests Link Between Hormone Melatonin and Type 2 Diabetes
5. Princess Margaret breast cancer research finds new drug target companion prognostic test for hormone therapy resistance
6. More Evidence Shows Hormone Therapy May Increase Breast Cancer Risk
7. Artificial Ovaries Could Potentially Deliver Hormone Therapy
8. Mindfulness from meditation associated with lower stress hormone
9. Should Short Boys Take Growth Hormone?
10. Hormone Pills in Menopause May Carry Gallstone Side Effects
11. Study examines outcomes of screening mammography for age, breast density, hormone therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hormone Shows Potential as Diabetes Treatment in Mice
(Date:5/21/2017)... ... May 21, 2017 , ... For more than 20 ... a wide range of knives and swords, from functional to fantasy. United Cutlery has ... with sleek, modern designs that defy tradition. , Offering a range of weapons and ...
(Date:5/19/2017)... ... ... In a continuous effort to raise awareness of autism and common toxins ... in natural and organic latex mattresses, has announced that they will donate $1 to ... their recent viral Facebook video receives, up to $10,000.00. , The luxury ...
(Date:5/19/2017)... Mo (PRWEB) , ... May 19, 2017 , ... When ... May 20, his name will already appear on two major research studies that could ... been working with Dr. Matt Daggett, KCU alumnus and an orthopedic surgeon, alongside an ...
(Date:5/19/2017)... ... May 19, 2017 , ... ... retirement planning assistance to families and business owners in the region, is embarking ... for MS sufferers and their families. , Multiple sclerosis (MS) is a demyelinating ...
(Date:5/19/2017)... Atlanta, GA (PRWEB) , ... May 19, 2017 , ... ... D. Miller knows the importance of prostate cancer screenings. Early detection of the ... Miller, head of robotic surgery at Georgia Urology , stands alongside the Georgia ...
Breaking Medicine News(10 mins):
(Date:5/18/2017)... , May 18, 2017  Two Bayer U.S. ... Association (HBA) during its recent 28 th ... City.  The event showcases HBA,s longstanding mission of furthering ... of healthcare. Cindy Powell-Steffen , senior ... U.S. Radiology division, and Libby Howe , a ...
(Date:5/12/2017)... 12, 2017  The China and Canada ... consumes less water, energy and detergent, and features a powerful disinfection ... a shoebox-sized washing machine that washes and sanitizes women,s panties or ... ... compact, and does not require an external water inlet. ...
(Date:5/10/2017)... -- The Corporate Whistleblower Center says, "We are urging ... to call us anytime at 866-714-6466 if they possess ... a substantial scheme to overbill Medicare. We are ... of a medical equipment company if their employer ... practice groups with extra generous incentives to use, or ...
Breaking Medicine Technology: