Navigation Links
Hormone Replacement May Cut Risk for Age-Linked Eye Disease
Date:4/14/2008

Estrogen may prevent advanced macular degeneration, study finds

MONDAY, April 14 (HealthDay News) -- Postmenopausal women who take hormones have a lower risk of developing advanced age-related macular degeneration, especially if they took oral contraceptives in the past, a U.S. study finds.

Age-related macular degeneration (AMD) affects 1.75 million Americans and is a leading cause of vision loss and blindness among older adults, according to background information in the study.

"Although genetics play a key role in susceptibility to AMD, environmental factors, such as smoking, are also important," the researchers wrote. "Evidence of higher rates of AMD in women than in men and links between AMD and cardiovascular disease suggested a role for estrogen" in the development of the condition, they added.

The researchers from Brigham and Women's Hospital and Harvard Medical School in Boston examined data on almost 75,000 postmenopausal women in the Nurses' Health Study. They assessed estrogen-related factors such as postmenopausal hormone use, past use of oral contraceptives, ages at first period and menopause, and childbirth history.

Between 1980 and 2002, 554 of the women developed early AMD, and 334 women developed neovascular (advanced) AMD.

"Currrent postmenopausal hormone users had a notable 48 percent lower risk of neovascular (involving formation of new blood vessels) AMD compared with those who had never used postmenopausal hormones, although risk did not decline linearly with longer durations of use," the study authors wrote. "Risk was lowest for postmenopausal hormone users who had used oral contraceptives in the past."

However, the study found that current hormone users had a 34 percent higher risk of early AMD. There was no link between oral contraceptive use and early AMD. Women who'd given birth were 26 percent less likely to develop early AMD.

"Taken together, these findings suggest a role for estrogen in the pathogenesis of AMD that requires further research in specific early and late signs of disease." the researchers concluded.

The study was published in the April issue of the journal Archives of Ophthalmology.

More information

The U.S. National Eye Institute has more about AMD.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, April 14, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hormone Combo May Provide Reversible Male Birth Control Tool
2. Alert to Women: What Your Doctor Prescribed for Hormone Replacement May Be Killing You and Your Rights Are About to Be Taken Away
3. Thyroid Hormone Could One Day Treat Osteoporosis
4. Low levels of PYY hormone a very early indicator of type 2 diabetes
5. WHI follow-up study: Risks of long-term hormone therapy continue to outweigh benefits
6. Cancer risk slightly higher for women in discontinued hormone treatment trial
7. Health risks after cessation of postmenopausal hormone therapy
8. Heart Hormones Beat Back Cancers in Mice
9. Weill Cornell team identifies potential new drug targets against hormone-dependent breast cancer
10. Hormone replacement therapy appears to have no effect on risk and severity of rheumatoid arthritis
11. Hormone therapy increases frequency of abnormal mammograms, breast biopsies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hormone Replacement May Cut Risk for Age-Linked Eye Disease
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... The Visiting ... Day Market. Featuring a collection of specialty vendors and unique items from across the ... and quality-focused health and wellness services offered by the VNA. The boutique will ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in ... awarded a contract by the Center for Medicare and Medicaid Services (CMS). The ... enterprise use of Agile methodologies in a consistent and high value manner across ...
(Date:10/12/2017)... , ... October 12, 2017 , ... Planet Fitness, one ... U.S., announced today its plans to open a flagship location in Covington, LA at ... former Rooms To Go store next to Office Depot in the Holiday Square shopping ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the ... to develop to enable prevention of a major side effect of chemotherapy in ... in pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand ... Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness will be ... Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... The Rebound mobile app is poised to become a vital ... prescription drug addiction. The app empowers users to develop an ... their dosage in a safe, controlled manner while maximizing well-being. ... 100,000 people to sign up will enjoy 3 months of ... ...
(Date:9/25/2017)... --  Montrium , an industry leader in powerful ... Trial Master Files & Inspection Readiness Conference ( ... Services has selected eTMF Connect to ... a leading European contract research organization (CRO), will ... enable greater collaboration with sponsors, improve compliance and ...
Breaking Medicine Technology: