Navigation Links
Hormone Replacement May Cut Risk for Age-Linked Eye Disease
Date:4/14/2008

Estrogen may prevent advanced macular degeneration, study finds

MONDAY, April 14 (HealthDay News) -- Postmenopausal women who take hormones have a lower risk of developing advanced age-related macular degeneration, especially if they took oral contraceptives in the past, a U.S. study finds.

Age-related macular degeneration (AMD) affects 1.75 million Americans and is a leading cause of vision loss and blindness among older adults, according to background information in the study.

"Although genetics play a key role in susceptibility to AMD, environmental factors, such as smoking, are also important," the researchers wrote. "Evidence of higher rates of AMD in women than in men and links between AMD and cardiovascular disease suggested a role for estrogen" in the development of the condition, they added.

The researchers from Brigham and Women's Hospital and Harvard Medical School in Boston examined data on almost 75,000 postmenopausal women in the Nurses' Health Study. They assessed estrogen-related factors such as postmenopausal hormone use, past use of oral contraceptives, ages at first period and menopause, and childbirth history.

Between 1980 and 2002, 554 of the women developed early AMD, and 334 women developed neovascular (advanced) AMD.

"Currrent postmenopausal hormone users had a notable 48 percent lower risk of neovascular (involving formation of new blood vessels) AMD compared with those who had never used postmenopausal hormones, although risk did not decline linearly with longer durations of use," the study authors wrote. "Risk was lowest for postmenopausal hormone users who had used oral contraceptives in the past."

However, the study found that current hormone users had a 34 percent higher risk of early AMD. There was no link between oral contraceptive use and early AMD. Women who'd given birth were 26 percent less likely to develop early AMD.

"Taken together, these findings suggest a role for estrogen in the pathogenesis of AMD that requires further research in specific early and late signs of disease." the researchers concluded.

The study was published in the April issue of the journal Archives of Ophthalmology.

More information

The U.S. National Eye Institute has more about AMD.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, April 14, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hormone Combo May Provide Reversible Male Birth Control Tool
2. Alert to Women: What Your Doctor Prescribed for Hormone Replacement May Be Killing You and Your Rights Are About to Be Taken Away
3. Thyroid Hormone Could One Day Treat Osteoporosis
4. Low levels of PYY hormone a very early indicator of type 2 diabetes
5. WHI follow-up study: Risks of long-term hormone therapy continue to outweigh benefits
6. Cancer risk slightly higher for women in discontinued hormone treatment trial
7. Health risks after cessation of postmenopausal hormone therapy
8. Heart Hormones Beat Back Cancers in Mice
9. Weill Cornell team identifies potential new drug targets against hormone-dependent breast cancer
10. Hormone replacement therapy appears to have no effect on risk and severity of rheumatoid arthritis
11. Hormone therapy increases frequency of abnormal mammograms, breast biopsies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hormone Replacement May Cut Risk for Age-Linked Eye Disease
(Date:1/17/2017)... ... January 17, 2017 , ... Achieve ... Desert, is opening a new office in San Clemente, California this month. Achieve ... in Southern California, successfully treating individuals struggling with major depression. Depression impacts over ...
(Date:1/17/2017)... , ... January 17, 2017 , ... ... – will lecture to primary eye care practitioners on the latest breakthroughs in ... upcoming 13th Semi-Annual Continuing Education Symposium, according to eye surgeon, Jeffrey Martin, MD, ...
(Date:1/17/2017)... ... January 17, 2017 , ... Wettstein Agencies, a Denver ... business professionals throughout central Colorado, is joining local nonprofit Aurora Warms The Night ... The Night organization is committed to breaking the cycle of homelessness and poverty ...
(Date:1/17/2017)... ... January 17, 2017 , ... Physicians Education Review®, LCC (PER®) ... speaker for the 34th Annual Miami Breast Cancer Conference®, on March 9-12, 2017 ... Phil Talamo, said, “We are delighted to have Sandra Lee join us as ...
(Date:1/17/2017)... ... January 17, 2017 , ... Today, FloSports , a ... announced a new agreement as part of a long-term extension of their media partnership. ... the airing of some of the sport’s premier events exclusively on FloWrestling.com as well ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... -- Research and Markets has announced the addition of ... to their offering. ... The global fluoropolymer market in the healthcare industry to grow ... Global Fluoropolymer Market in the Healthcare Industry 2016-2020, has been ... experts. The report covers the market landscape and its growth prospects ...
(Date:1/17/2017)... Jan. 17, 2017 Following an initial ... praised the Food and Drug Administration,s (FDA,s) final ... Drug Products by Pharmacies and Outsourcing Facilities." In ... limitation on pre-packaging -- which would have put ... to long term care (LTC) pharmacies.  ...
(Date:1/17/2017)... ReportsnReports.com adds "Anaphylaxis - Pipeline Review, H2 2016" ... Anaphylaxis,s therapeutic pipeline with comprehensive information on the therapeutic development ... assessment by drug target, mechanism of action (MoA), route of ... featured news and press releases. ... Complete report on H2 2016 pipeline ...
Breaking Medicine Technology: