Navigation Links
Hormone Combo May Provide Reversible Male Birth Control Tool
Date:3/28/2008

Testosterone coupled with progestin effectively suppressed sperm production

FRIDAY, March 28 (HealthDay News) -- A combination of testosterone and progestin suppresses sperm production faster and more completely than testosterone alone, according to an analysis by an international team of researchers.

The scientists said that hormonal contraception may become a safe, effective and reversible form of male birth control.

"It is possible to suppress sperm output to concentrations that are comparable with reliable contraception in most, but not all men. The rate of suppression is comparable to that achieved after a vasectomy," lead author Peter Y. Liu, an associate professor at the University of Sydney, Australia, said in a prepared statement.

Testosterone and other male hormones create "negative feedback" in the male reproductive system, which suppresses sperm production.

In this study, Liu and colleagues analyzed 30 male hormonal contraceptive studies that included a total of 1,756 men, aged 18 to 51. In these studies, conducted from 1990 to 2006, the men received different preparations of testosterone, with or without various preparations of the hormone progestin.

Testosterone is the primary male sex hormone. Progestin (a synthetic progesterone), which is used in combination with estrogen for female contraception, is not ordinarily produced by men.

The analysis revealed that the combination of testosterone and progestin was more effective at suppressing sperm production that testosterone alone.

"Progestin co-administered with testosterone increased both the rate and extent of suppression. It also may make long-term hormonal contraception safer by reducing the dose of testosterone needed for maintenance contraception," Liu said.

The analysis also showed that treatment suppressed sperm output more quickly in white males but not as completely as in non-whites. Younger men with lower testosterone levels also had faster sperm production suppression.

The review authors also found that it's difficult to predict which men will respond best to this combination hormonal contraception.

"Considerable progress has been made toward finding an effective combination of these two hormones. However, the current analysis didn't take into account the different types of progestins, so more research will need to be done to find the optimum therapy," Liu said.

The study was published in the Journal of Clinical Endocrinology & Metabolism.

More information

The American Academy of Family Physicians has more about birth control.



-- Robert Preidt



SOURCE: Endocrine Society, news release, March 25, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Alert to Women: What Your Doctor Prescribed for Hormone Replacement May Be Killing You and Your Rights Are About to Be Taken Away
2. Thyroid Hormone Could One Day Treat Osteoporosis
3. Low levels of PYY hormone a very early indicator of type 2 diabetes
4. WHI follow-up study: Risks of long-term hormone therapy continue to outweigh benefits
5. Cancer risk slightly higher for women in discontinued hormone treatment trial
6. Health risks after cessation of postmenopausal hormone therapy
7. Heart Hormones Beat Back Cancers in Mice
8. Weill Cornell team identifies potential new drug targets against hormone-dependent breast cancer
9. Hormone replacement therapy appears to have no effect on risk and severity of rheumatoid arthritis
10. Hormone therapy increases frequency of abnormal mammograms, breast biopsies
11. LA BioMed study finds hormone therapy increases frequency of abnormal mammograms, breast biopsies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2017)... NY (PRWEB) , ... September 19, 2017 , ... ... announced today the addition of strategic marketing leader, Denise Flannery, to its strategic ... Marketing, Brand and Management Consultant, Denise will work with clients across different industries ...
(Date:9/19/2017)... TX (PRWEB) , ... September 19, 2017 , ... ... non-profit organization devoted exclusively to funding innovative lymphoma research and serving the lymphoma ... – will return to Texas as a part of its national Swirl: A ...
(Date:9/19/2017)... , ... September 19, 2017 , ... ... Society of Professional Benefit Administrators (SPBA) hosted “Expanding Your Success” with an ... Members as it focused on best practices for third party administrators (TPAs) related ...
(Date:9/19/2017)... ... September 19, 2017 , ... Big Barker , a ... September 2016 donation of dog beds to the K9 officers of the Allentown, ... for its contribution from city and state officials. , The U.S. House ...
(Date:9/19/2017)... ... September 19, 2017 , ... The ISO 9001 standard ... businesses and organizations become more efficient and improve customer satisfaction. ISO 9001:2015 was released ... own QMS, with a deadline of September 2018. , As described in ...
Breaking Medicine News(10 mins):
(Date:8/29/2017)... ivWatch, LLC, the leading provider of continuous monitoring devices ... been awarded an Innovative Technology contract from Vizient, Inc., the largest ... ... the early detection of peripheral IV infiltration and extravasation events ... The Innovative Technology contract was awarded to ivWatch ...
(Date:8/28/2017)... , Aug. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... on Monday, September 11, 2017, in New York ... executive officer, is scheduled to present at 11:05 a.m. Eastern ... accessed at http://ir.hill-rom.com/events.cfm . A recorded replay will be ... through December 10, 2017. ...
(Date:8/25/2017)... , Aug. 25, 2017  Innovation Zed ( www.innovationzed.com ), an Irish ... in South Yorkshire and Bassetlaw, England ... accessory used with diabetes patients as part of a national NHS Test ... ... InsulCheck Connect, a snap-on accessory for disposable ...
Breaking Medicine Technology: