Navigation Links
Hormone Combo May Provide Reversible Male Birth Control Tool
Date:3/28/2008

Testosterone coupled with progestin effectively suppressed sperm production

FRIDAY, March 28 (HealthDay News) -- A combination of testosterone and progestin suppresses sperm production faster and more completely than testosterone alone, according to an analysis by an international team of researchers.

The scientists said that hormonal contraception may become a safe, effective and reversible form of male birth control.

"It is possible to suppress sperm output to concentrations that are comparable with reliable contraception in most, but not all men. The rate of suppression is comparable to that achieved after a vasectomy," lead author Peter Y. Liu, an associate professor at the University of Sydney, Australia, said in a prepared statement.

Testosterone and other male hormones create "negative feedback" in the male reproductive system, which suppresses sperm production.

In this study, Liu and colleagues analyzed 30 male hormonal contraceptive studies that included a total of 1,756 men, aged 18 to 51. In these studies, conducted from 1990 to 2006, the men received different preparations of testosterone, with or without various preparations of the hormone progestin.

Testosterone is the primary male sex hormone. Progestin (a synthetic progesterone), which is used in combination with estrogen for female contraception, is not ordinarily produced by men.

The analysis revealed that the combination of testosterone and progestin was more effective at suppressing sperm production that testosterone alone.

"Progestin co-administered with testosterone increased both the rate and extent of suppression. It also may make long-term hormonal contraception safer by reducing the dose of testosterone needed for maintenance contraception," Liu said.

The analysis also showed that treatment suppressed sperm output more quickly in white males but not as completely as in non-whites. Younger men with lower testosterone levels also had faster sperm production suppression.

The review authors also found that it's difficult to predict which men will respond best to this combination hormonal contraception.

"Considerable progress has been made toward finding an effective combination of these two hormones. However, the current analysis didn't take into account the different types of progestins, so more research will need to be done to find the optimum therapy," Liu said.

The study was published in the Journal of Clinical Endocrinology & Metabolism.

More information

The American Academy of Family Physicians has more about birth control.



-- Robert Preidt



SOURCE: Endocrine Society, news release, March 25, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Alert to Women: What Your Doctor Prescribed for Hormone Replacement May Be Killing You and Your Rights Are About to Be Taken Away
2. Thyroid Hormone Could One Day Treat Osteoporosis
3. Low levels of PYY hormone a very early indicator of type 2 diabetes
4. WHI follow-up study: Risks of long-term hormone therapy continue to outweigh benefits
5. Cancer risk slightly higher for women in discontinued hormone treatment trial
6. Health risks after cessation of postmenopausal hormone therapy
7. Heart Hormones Beat Back Cancers in Mice
8. Weill Cornell team identifies potential new drug targets against hormone-dependent breast cancer
9. Hormone replacement therapy appears to have no effect on risk and severity of rheumatoid arthritis
10. Hormone therapy increases frequency of abnormal mammograms, breast biopsies
11. LA BioMed study finds hormone therapy increases frequency of abnormal mammograms, breast biopsies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2017)... , ... July 25, 2017 , ... ... ATM provider in the United States, today announced its partnership with financial technology ... , The foundation of the solution lies within Hyosung’s superior ATMs, assisted ...
(Date:7/25/2017)... ... July 25, 2017 , ... USHEALTH Group, Inc. has ... prestigious CEO World Awards®. The coveted annual CEO World Awards program encompasses the ... studies, corporate social responsibility, and milestones from every major industry in the world. ...
(Date:7/24/2017)... JACKSONVILLE, Florida (PRWEB) , ... ... ... Klaproth, Division Marketing Director,      (407) 916-7235, kklaproth(at)robinsmorton(dot)com , Robins ... guests joined together to celebrate the structural topping out of the new ...
(Date:7/24/2017)... ... July 24, 2017 , ... Cosmetic Town, an online plastic surgery information community, ... perform on a daily basis. , The new video series will feature board-certified ... at their practices. , When asked about the new video series, the senior ...
(Date:7/24/2017)... (PRWEB) , ... July 24, 2017 , ... ... in Oakland, California effectively destroyed the construction site and threatened numerous homes and ... July 7th article on NBCLosAngeles.com. Los Angeles Area consulting firm Fire ...
Breaking Medicine News(10 mins):
(Date:7/12/2017)... CarpalAID is a revolutionary new product that relieves painful carpal tunnel ... syndrome affects more than 8 million people a year. Women suffer ... common methods of treating CTS are painful surgery, the use of ... ... is a clear patch worn on the palm of the hand. ...
(Date:7/11/2017)... , July 11, 2017  Bayer has awarded grants totaling ... as part of its prestigious Bayer Hemophilia Awards Program (BHAP). ... Philadelphia and Uniformed Services University of ... among the winners. Grant recipients were announced last night during ... (ISTH) 2017 Congress, Berlin, Germany . ...
(Date:7/11/2017)... , July 11, 2017  Dr. Echenberg, founder of Echenberg Institute, ... program to patients who suffer from painful intercourse and other painful pelvic ... vaginal atrophy due to menopause. ... VuVatech LLC ... created by Sarasota, Florida -based start-up company, VuVatech LLC, ...
Breaking Medicine Technology: