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Hormonal Therapies Offer Effective Solutions for Many Adult Women With Acne
Date:7/29/2009

ogen (ethinyl estradiol for most contraceptive pills) and a progestin. The estrogen component decreases the production of testosterone and other androgens by the ovaries and decreases the amount of active testosterone in the body.

Some progestins may actually mimic the activity of testosterone on the oil gland and thereby worsen acne. Therefore, Dr. Schlosser primarily recommends oral contraceptives that contain one of the following progestins: norgestimate, desogestrel, or drospirenone, all of which demonstrate low or no risk of increasing the activity of the testosterone receptor.

"Combination oral contraceptives can be very beneficial in the treatment of acne in appropriately selected women, and several different oral contraceptives have been shown to be effective in clinical studies," said Dr. Schlosser. "But the treatment of acne with combination oral contraceptives needs to be targeted to each patient's individual needs, and patients should be monitored regularly to ensure the safety and effectiveness of their particular therapy."

Dr. Schlosser cautioned that improvement of acne with hormonal therapy does not occur overnight and requires at least three months of continuous use before a judgment about effectiveness should be made. In many cases, patients need to continue using oral contraceptives to sustain their results over time. However, some patients can stop hormonal therapy and maintain clear skin with the regular use of a topical retinoid.

"For many women with adult-onset acne, combination hormonal therapy can provide excellent results," added Dr. Schlosser. "Women who think they might be good candidates should discuss their options with their dermatologist who can offer a customized treatment regimen and continual monitoring to ensure optimal results."

To learn more about acne, visit the AcneNet section of www.skincarephysicians.com, a Web site developed by
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SOURCE American Academy of Dermatology
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