Navigation Links
Hope for patients with HIV-associated cognitive impairment
Date:8/14/2012

Current drug therapy for patients with HIV is unable to control the complete replication of the virus in the brain. The drugs therefore do not have any effect against the complications associated with neurocognitive impairment in patients with HIV. New research by Joseph Steiner and colleagues from Johns Hopkins University has discovered that a group of plant polyphenols known as catechins, which naturally occur in green tea and the seed of the cacao tree, may help in the prevention of these neurological complications. Their work is published online in Springer's Journal of NeuroVirology.

Previous research has established the critical role of a protein called brain-derived neurotrophic factor (BDNF) in supporting the survival and growth of neurons in the brain. This protein is active in areas of the brain vital to learning, memory and higher thinking. Patients with HIV have been found to have lower levels of BDNF in their brains than healthy individuals suggesting that this could be directly responsible for the cognitive impairment suffered.

In their research, Steiner and colleagues analysed the effects of 2000 compounds, containing both natural substances and FDA-approved drugs, on brain cells in the laboratory. They identified a series of compounds which had the potential to help protect neurons in the brain. Nine of these were related to epicatechin, which is found in cocoa and green tea leaves. Further screening and comparison with resveratrol, the antioxidant found in red wine, specifically identified epicatechin and epigallocatechin gallate (EGCG) as being the most effective at helping protect neurons by inducing production of BDNF.

Although the antioxidant activities of epicatechin and EGCG are well documented, the discovery that they could be responsible for inducing production of BDNF is an exciting advancement in this area. The fact that these compounds readily cross the blood-brain barrier further increases their th
'/>"/>

Contact: Renate Bayaz
renate.bayaz@springer.com
49-622-148-78531
Springer
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Questions Guidelines on Radiation for Older Breast Cancer Patients
2. Study: Majority of older, early-stage breast cancer patients benefit from radiation after lumpectomy
3. Individualized care best for lymphedema patients, MU researcher says
4. Rhode Island Hospital study: Bariatric patients with obstructive sleep apnea fail to show symptoms
5. Patients Often Kept in Dark About Off-Label Drug Use: Study
6. Underinsured Heart Disease Patients Die Sooner, Study Finds
7. Doctors often dont disclose all possible risks to patients before treatment
8. Patients want more risks disclosed before treatment
9. No difference in death rates among patients exposed to common rheumatoid arthritis drugs
10. Weekends More Fatal for Older Patients With Head Injury: Study
11. Coach could be key in helping stroke patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... ... September 02, 2015 , ... A recent survey by Consumer Reports ( ... and its negative impact on consumers. It was reported that 33% are paying an ... as much as an extra $100 compared to last year. Among the drugs that ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... content, records and case management solutions and services to both government and commercial ... Re-sizing and Image Clean-up utility for IBM’s Datacap document capture platform. EDAC ...
(Date:9/2/2015)... ... September 02, 2015 , ... Available in select spas and ... PIONNIÈRE XMF Perfection Youth Rich Cream , an evolution of the classic PIONNIÈRE ... a lipid-replenishing marine oil for intense nourishing and moisturizing. Phytomer exclusive ingredient XMF ...
(Date:9/2/2015)... ... , ... Dr. Robert G. Schwartz , the principal of Piedmont Physical ... Russian martial art system that is also a philosophy of life that focuses on ... back to the 10th century, is a Russian Martial Art that has four key ...
(Date:9/1/2015)... ... September 01, 2015 , ... An August 25 article ... surgeries conducted each year on teenagers, quoting a New York City-area plastic surgeon ... plastic surgeon Payam Jarrah-Nejad, M.D., F.I.C.S., F.A.C.S., known more familiarly to patients and ...
Breaking Medicine News(10 mins):Health News:Watertree Health President Responds to Consumer Reports Survey on Rising Prescription Drug Prices 2Health News:EDAC Systems, Inc. announces a new version of its Image Enhancement and Image Re-Sizing utility EDAC’s PurePAGE® 2Health News:EDAC Systems, Inc. announces a new version of its Image Enhancement and Image Re-Sizing utility EDAC’s PurePAGE® 3Health News:Phytomer announces PIONNIÈRE XMF Perfection Youth Rich Cream 2Health News:Phytomer announces PIONNIÈRE XMF Perfection Youth Rich Cream 3Health News:Phytomer announces PIONNIÈRE XMF Perfection Youth Rich Cream 4Health News:Dr. Robert G. Schwartz Achieves Certification in Russian Martial Art “Systema” and Focuses on Integrating Techniques & Principles into Health Care Delivery 2Health News:Dr. Robert G. Schwartz Achieves Certification in Russian Martial Art “Systema” and Focuses on Integrating Techniques & Principles into Health Care Delivery 3Health News:Teen Plastic Surgery Article Understates the Most Important Realities of Procedures on Young People, Notes Dr. J 2
... Carnegie Mellon University neuroscientist Marcel Just and Stanford postdoctoral ... theory of brain function that provides answers to one ... the human brain organize itself to give rise to ... spatial reasoning? Just and Varmas theory, called 4CAPS, is ...
... Children,s Research Hospital, and Help Kick Off the Fourth ... to be Held Monday, Nov. 19 at 11 a.m. at ... Visitors to Bryant Park on,Monday morning will have the ... the finishing touches on a three-dimensional canvas mural derived,from a ...
... Delivery Service Launches Highly Accessible and ... Affordable Program ... NEW YORK, Nov. 15 Chefs Diet(R), the leading meal,delivery service ... launch of My Solution -- a nationwide program that provides,chef-prepared, gourmet frozen ...
... VERNON HILLS, Ill., Nov. 15 Winston,Laboratories, Inc., ... development of products for pain management, and Getting,Ready ... no active operations, have signed a merger agreement ... The combined company will be renamed,Winston Pharmaceuticals, Inc., ...
... International,Technology Inc. (MDLH. PK) ( http://www.mitcanada.ca , http://www.mitinvest.ca ... completed its,10QSB quarterly reports (December 2006, March 2007 ... with its filings. Medical International Technology Inc. ... means to help prevent the spread of deadly ...
... when applying for driver,s licenses, researchers suggest , THURSDAY, ... epilepsy, simply asking how often they have seizures doesn,t ... research suggests. , Reminding patients to keep written records ... may be unaware of some seizures, said the University ...
Cached Medicine News:Health News:Carnegie Mellon neuroscientist proposes new theory of brain flexibility 2Health News:Carnegie Mellon neuroscientist proposes new theory of brain flexibility 3Health News:American Airlines Invites the Public to Join Marlo Thomas and St. Jude Patients to Create One-of-a-Kind Mural to Celebrate 80 Years of Service in the Greater New York Area 2Health News:American Airlines Invites the Public to Join Marlo Thomas and St. Jude Patients to Create One-of-a-Kind Mural to Celebrate 80 Years of Service in the Greater New York Area 3Health News:American Airlines Invites the Public to Join Marlo Thomas and St. Jude Patients to Create One-of-a-Kind Mural to Celebrate 80 Years of Service in the Greater New York Area 4Health News:CHEFS DIET(R) Introduces My Solution 2Health News:Getting Ready Corporation and Winston Laboratories, Inc. Announce Merger Agreement 2Health News:Getting Ready Corporation and Winston Laboratories, Inc. Announce Merger Agreement 3Health News:Getting Ready Corporation and Winston Laboratories, Inc. Announce Merger Agreement 4Health News:Some Epilepsy Patients Not Always Aware of Seizures 2
(Date:9/2/2015)...  MGC Diagnostics Corporation (NasdaqCM: MGCD), a global medical ... its financial results for the third quarter of fiscal ... at 4:30 p.m. ET on Thursday, September 10, 2015. ... quarter of fiscal 2015 after the markets close on ... dial (877) 317-6789 or (412) 317-6789 to access the ...
(Date:9/2/2015)... YORK , Sept. 2, 2015 Relmada ... novel therapies for the treatment of chronic pain, announced ... meetings at both the FBR Second Annual Healthcare Conference ... as follows: FBR Second Annual Healthcare Conference ... Boston No presentation, investor ...
(Date:9/2/2015)... Belgium , Sept. 2, 2015 /PRNewswire/ -- VolitionRx Limited ... blood-based diagnostic tests for a broad range of cancer types ... Cameron Reynolds , is scheduled to present at the ... being held September 8-10, 2015 in New York, ... Mark Eccleston will be presenting at the CNAPS ...
Breaking Medicine Technology:MGC Diagnostics Corporation to Report Third Quarter Fiscal 2015 Financial Results on Thursday, September 10, 2015 2Relmada Therapeutics to Participate in Two Upcoming Investor Conferences 2VolitionRx to Present at Rodman & Renshaw 17th Annual Global Investment Conference in New York and CNAPS IX Conference in Berlin on September 9 and 11, 2015 2VolitionRx to Present at Rodman & Renshaw 17th Annual Global Investment Conference in New York and CNAPS IX Conference in Berlin on September 9 and 11, 2015 3VolitionRx to Present at Rodman & Renshaw 17th Annual Global Investment Conference in New York and CNAPS IX Conference in Berlin on September 9 and 11, 2015 4
... MOUNTAIN VIEW, Calif., Dec. 7, 2010 Alexza Pharmaceuticals, Inc. ... has scheduled an End-of Review meeting with the U.S. Food ... Response Letter (CRL) regarding the Company,s New Drug Application (NDA) ... Information Package to the FDA in preparation for the meeting, ...
... Dec. 7, 2010 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc. ("China-Biotics" ... the leading developer, manufacturer and distributor of probiotics ... from the Company,s research and development department presented ... Application and Equipment seminar in Hangzhou, China on ...
Cached Medicine Technology:Alexza Pharmaceuticals Provides Regulatory Update for AZ-004 (Staccato® Loxapine) 2Alexza Pharmaceuticals Provides Regulatory Update for AZ-004 (Staccato® Loxapine) 3China-Biotics Attended National Probiotics Seminar 2China-Biotics Attended National Probiotics Seminar 3
... The VersaPulse PowerSuite holmium laser ... properties for precise, virtually bloodless procedures. ... fragmenting urinary and gall bladder stones ... ideal multipurpose surgical tool. Because its ...
... Nd:YAG technology has allowed for perfecting mini-invasive ... of various pathologies with a considerable social ... for reducing the post-operatory times and represents ... costs in all hospital structures.,DEKAs family of ...
... have to choose. The Apogee Elite ... 755nm Alexandrite laser and a high ... in one convenient unit. The ... for hair removal, pigmented lesions, facial ...
Single use trocar with non-conductive sleeves for gaining and maintaining thoracic access., ,THORACOPORT™ devices are trocars used to gain access to the thoracic cavity for use in video assis...
Medicine Products: