Date:8/3/2009

ssets acquired from Third Wave and Cytyc in fiscal 2009 and 2008, respectively 4,065 2,900 Restructuring charge - 6,383 Acquired in-process research and development related to the Cytyc merger - 370,000 Income tax effect of reconciling items (58,512)(2) (51,142)(3) ------- ------- Non-GAAP adjusted net income $229,270 $221,740 ======== ======== EBITDA Non-GAAP adjusted net income $229,270 Interest expense, net 52,058 Provision for income taxes 120,761 Depreciation and amortization not adjusted above 49,499 ------ Adjusted EBITDA $451,588 ======== EXPLANATORY NOTES: ------------------ (1) Non-GAAP adjusted earnings per share was calculated based on 258,574 and 247,678 weighted average diluted shares outstanding for the nine months ended June 27, 2009 and June 28, 2008, respectively. (2) To reflect an estimated annual effective tax rate of 34.5% on a non-GAAP basis. (3) To reflect an estimated annual effective tax rate of 35.6% on a non-GAAP basis.

Non-GAAP Financial Guidance:

This press release also includes estimates of future non-GAAP adjusted earnings and earnings per share. A reconciliation of these amounts to expected GAAP results is presented below:

               Three                         Twelve
              Months                         Months
               Ended             D
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SOURCE  Hologic, Inc.
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