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Higher testosterone may raise risk of heart disease in elderly men
Date:7/1/2010

her total testosterone level relates to an increased risk of coronary disease. Men whose total testosterone was in the highest quartile (greater than or equal to 495 nanograms per deciliter, or ng/dL) had more than twofold the risk of coronary disease compared with men in the lowest quartile (below 308 ng/dL).

Other important measures of testosterone in the body and of a protein that tightly binds with testosterone (sex hormone-binding globulin) also showed a close relationship between testosterone and coronary heart disease, Sueoka said.

The investigators did not divide the men by normal or abnormal testosterone levels because the definition of abnormal levels depends on many factors, including increasing age. In fact, says Sueoka, "Men with the highest testosterone could potentially be at risk for heart disease regardless of the definition of "normal" levels."

"One day testosterone measurements may be used to help predict which men are more likely to develop cardiovascular disease," she said. "But we need more studies to confirm that high testosterone is a risk factor for heart disease."


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Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Page: 1 2

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