Navigation Links
Higher soy intake prior to lung cancer diagnosis linked to longer survival in women
Date:3/25/2013

In this News Digest:

  • Summary of a study being published online March 25, 2013 in the Journal of Clinical Oncology, reports that Chinese women who consumed more soy before being diagnosed with lung cancer lived longer compared with those who consumed less soy.
  • Quote for attribution to Jyoti Patel, MD, American Society of Clinical Oncology Cancer Communications Committee member and lung cancer expert
  • Links to additional information on Cancer.Net, ASCO's cancer information Website

New results from a large observational follow-up study conducted in Shanghai, China, indicate that women with lung cancer who consumed more soy food prior to their cancer diagnosis lived longer than those who consumed less soy. The study, published March 25 in the Journal of Clinical Oncology, provides the first scientific evidence that soy intake has a favorable effect on lung cancer survival.

"To our knowledge, this is the first study to suggest an association between high soy consumption before a lung cancer diagnosis and better overall survival," said lead study author Gong Yang, MD, MPH, a research associate professor at Vanderbilt University Medical Center. "Although the findings are very promising, it's too early to give any dietary recommendations for the general public on the basis of this single study."

Lung cancer is the leading cause of cancer-related death among women worldwide, with only one in seven patients surviving for 5 years after diagnosis. Emerging evidence suggests that female hormones, particularly estrogens, may affect lung cancer outcomes. Soy contains isoflavones, estrogen-like substances that are also known to affect molecular pathways involved in tumor development and growth.

A recent study by the same research team showed that high intake of soy food was associated with a 40 percent decrease in lung cancer risk.

This new study assessed the impact of soy intake on lung cancer survival among participants of the Shanghai Women's Health Study, which tracked cancer incidence in 74,941 Shanghai women. Information on usual dietary intake of soy food (soy milk, tofu, fresh and dry soybeans, soy sprouts, and other soy products) was collected in-person at study enrollment and again two years later. Soy food and isoflavone content of various food products was calculated based on the Chinese Food Composition tables. During the course of the study, 444 women were diagnosed with lung cancer. The median time between the first dietary assessment and cancer diagnosis was 5.8 years.

In this analysis, patients were divided into three groups according to soy food intake prior to lung cancer diagnosis. The highest and lowest intake levels were equivalent to approximately 4 oz or more and 2 oz or less tofu per day, respectively. Patients with the highest soy food intake had markedly better overall survival compared with those with the lowest intake ─ 60 percent of patients in the highest intake group and 50 percent in the lowest intake group were alive at twelve months after diagnosis.

The risk of death decreased with increasing soy intake until the intake reached a level equivalent to about 4 oz of tofu per day. Researchers found no additional survival benefit from consuming higher amounts of soy. Similar trends were observed when dietary isoflavone intake was evaluated.

The findings may not necessarily apply beyond this study's population, which has a very low prevalence of cigarette smoking, a known risk factor for the development of lung cancer, and postmenopausal hormone replacement therapy use, a factor that may negatively affect lung cancer prognosis. In addition, the overall soy food intake is higher in Chinese women than in Western women.

"But given the increasing popularity of soy food in the U.S. and elsewhere, and a sizable number of women who don't smoke, the results of this study could have wider relevance," said Yang.

Future research will explore whether consumption of soy food after diagnosis of lung cancer affects survival, particularly among patients with early-stage disease, who may benefit most from a nutritional intervention.

This research was supported by the U.S. National Cancer Institute and conducted by investigators at Vanderbilt University in collaboration with those from the Shanghai Cancer Institute and NCI.

ASCO Perspective
Jyoti Patel, MD, ASCO Cancer Communications Committee member and lung cancer expert

"This study provides some early evidence that consuming large amounts of soy food may help women, particularly never smokers, live longer if they should develop lung cancer."


'/>"/>
Contact: Nicole Racadag
nicole.racadag@asco.org
571-483-1354
American Society of Clinical Oncology
Source:Eurekalert

Related medicine news :

1. Hip surgery complication rate higher than previously reported
2. Cancer drug shortages mean higher costs and greater risk for patients
3. Women Abused in Childhood at Higher Odds of Having Child With Autism: Study
4. Certain Men May Face Higher Risk of Brain Injury
5. In Seriously Ill Kids, Obesity May Be Tied to Higher Death Risk: Study
6. Sweet Drinks Tied to Higher Calorie Consumption in Kids
7. Obese New Mothers May Have Higher Heart Attack, Stroke Risk
8. Heavier Pregnant Women May Face Higher C-Section Risk
9. Lack of aspirin before angioplasty linked with higher mortality
10. Weight loss linked to higher risk with implanted defibrillators
11. Black Breast Cancer Survivors Face Higher Heart Failure Risk: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... US ... Yoga Studio in Dover, NH to direct high-performance kids yoga training. ChildLight Yoga Studio ... seacoast, just one hour from Boston. , ChildLight Yoga Studio founder Lisa Flynn expresses ...
(Date:2/5/2016)... ... 2016 , ... Give To Cure today announced that it is ... Give To Cure’s campaign that is crowdfunding clinical trials to help find cures faster ... through a smart device. In 2015 alone, Venmo processed $7.5 billion in transactions among ...
(Date:2/5/2016)... ... February 05, 2016 , ... Dr. Justin Scott and Dr. ... Annual No Cost Dental Day to individuals in need. The event is scheduled to ... No Cost Dental Day is to provide dental care to community members in need. ...
(Date:2/5/2016)... Pekin, IL (PRWEB) , ... February 05, 2016 , ... ... in disguised form as a dream. A hallmark feature of patients with eating disorders ... and needs. The eating disorder behaviors and obsessions are regarded as maladaptive means for ...
(Date:2/5/2016)... ... , ... Calls Blacklist has just been updated by mobile app developer Vlad ... has fixed known bugs within the app. Calls Blacklist allows its users to only ... any of their device’s battery power or memory. It provides a powerful call blocker ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 2016  SciClone Pharmaceuticals, Inc. (NASDAQ: SCLN ... into a settlement agreement with the United States ... SEC,s investigation into possible violations of the Foreign ... the settlement agreement, SciClone has agreed to pay ... interest and a penalty.  This payment is in ...
(Date:2/4/2016)... , Feb. 4, 2016 Global ... competitive market to drive long-term market growth ... common set of chronic disorders that affect 5–7% ... in terms of their symptoms and key patient ... dysregulation of immune pathways and an inappropriate immune ...
(Date:2/4/2016)... DIEGO, Feb. 4, 2016  Aethlon Medical, Inc. ... affinity biofiltration devices to treat life-threatening diseases, today ... 2016 ended December 31, 2015. ... objectives set forth in our last quarterly call, ... reinforce our long-term objective to establish the Aethlon ...
Breaking Medicine Technology: