Navigation Links
Higher levels of obesity associated with increased risk of death
Date:1/1/2013

CHICAGO In an analysis of nearly 100 studies that included approximately 3 million adults, relative to normal weight, overall obesity (combining all grades) and higher levels of obesity were both associated with a significantly higher all-cause risk of death, while overweight was associated with significantly lower all-cause mortality, according to a study in the January 2 issue of JAMA.

"Estimates of the relative mortality risks associated with normal weight, overweight, and obesity may help to inform decision making in the clinical setting," according to background information in the article.

Katherine M. Flegal, Ph.D., of the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Md., and colleagues conducted a study to compile and summarize published analyses of body mass index (BMI) and all-cause mortality that provide hazard ratios (HRs) for standard BMI categories. For the review and meta-analysis, the researchers identified 97 studies that met inclusion criteria, which provided a combined sample size of more than 2.88 million individuals and more than 270,000 deaths. Regions of origin of participants included the United States or Canada (n = 41 studies), Europe (n = 37), Australia (n = 7), China or Taiwan (n = 4), Japan (n = 2), Brazil (n = 2), Israel (n = 2), India (n = l), and Mexico (n = l).

All-cause mortality HRs for overweight (BMI of 25-<30), obesity (BMI of ≥30), grade 1 obesity (BMI of 30-<35), and grades 2 and 3 obesity (BMI of ≥35) were calculated relative to normal weight (BMI of 18.5-<25).

The researchers found that the summary HRs indicated a 6 percent lower risk of death for overweight; a 18 percent higher risk of death for obesity (all grades); a 5 percent lower risk of death for grade 1 obesity; and a 29 percent increased risk of death for grades 2 and 3 obesity.

The authors note that the finding that grade 1 obesity was not associated with higher mortality suggests that that the excess mortality in obesity may predominantly be due to elevated mortality at higher BMI levels.

The researchers add that their findings are consistent with observations of lower mortality among overweight and moderately obese patients. "Possible explanations have included earlier presentation of heavier patients, greater likelihood of receiving optimal medical treatment, cardioprotective metabolic effects of increased body fat, and benefits of higher metabolic reserves."

The use of predefined standard BMI groupings can facilitate between-study comparisons, the authors conclude.


'/>"/>

Contact: Karen Hunter
ksh7@cdc.gov
404-639-3286
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Chronic Worry Linked to Higher Risk of PTSD
2. Benefits of higher oxygen, breathing device persist after infancy
3. A New Review Reveals How “Jump Manual” Can Help People Jump Higher - Tony Nguyen
4. Daimer Debuts Carpet Cleaners For Car Dealerships Seeking Interior Auto Detailing Steam Cleaner Machines Featuring Higher Power and A Larger Water Capacity
5. Metro Atlanta ServiceMasters Team Up to Offer Higher Quality of Water Damage, Mold Removal, Carpet Cleaning and Fire Damage Services to Customers in North Georgia
6. Some Cancer Risks Higher in 9/11 Recovery Workers: Study
7. Chronic worriers at higher risk for PTSD
8. Children born prematurely are at higher risk of esophageal inflammation, cancer
9. Kids May Be at Slightly Higher Asthma Risk If Parents Had Infertility Treatments
10. Heart Drug Digoxin Tied to Higher Death Risk for Some Patients
11. Diabetes Rates Higher in Countries Using Lots of High Fructose Corn Syrup: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2016)... , ... December 03, 2016 ... ... Newall wins "Best Surgical Body Shaping" at the 2016 Anti-Aging & ... Paris, France. , The Aesthetic & Anti-Aging Medicine European Congress (AMEC) ...
(Date:12/4/2016)... ... , ... Responsible dental care hinges on regular brushing of the teeth. However, ... important necessity inspired an inventor from Las Vegas, Nev., to design the BRUSH PROPER. ... or avoid bad techniques of brushing the teeth in order to prevent cavities," he ...
(Date:12/2/2016)... ... ... twenty-four years, Doctors on Liens has published a directory of the top doctors ... When the company started in 1997, the directory was a single page focusing on ... ten-page directory features a vast array of medical specialists stretching from Sacramento to ...
(Date:12/2/2016)... ... , ... The annual time frame to change Medicare health and prescription drug ... 7th. Currently-enrolled Medicare beneficiaries who are looking to switch from their current plan to ... make changes during this period order for their new policy to go into effect ...
(Date:12/2/2016)... New York, NY (PRWEB) , ... December 02, 2016 , ... ... from high school and while 84 percent of parents report speaking with their child ... control, pornography and sexually transmitted diseases. , Mediaplanet is proud to announce the launch ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Research and Markets has announced the addition of the "R&D ... ... R&D Drug Pipeline Database: 1-Year Subscription Subscription ... online access to information about more than 21,000 project entries (files) ... in research & development. Pre-established and free search ...
(Date:12/2/2016)... December 2, 2016 Persistence Market ... market in its upcoming report titled, "Global Market Study on Cardiac ... CAGR of -1.4% between 2016 and 2024". The global cardiac ... 2015 and this is likely to decline to US$ ... global cardiac pacemaker market is anticipated to exhibit a ...
(Date:12/2/2016)... DUBLIN , Dec 2, 2016 Research ... Market Size, Share, Development, Growth and Demand Forecast to 2022" report ... , , ... revenue of $6 billion in 2015, and it is expected to grow ... ultrasound segment is expected to witness faster growth during the forecast period, ...
Breaking Medicine Technology: