Navigation Links
Higher levels of obesity associated with increased risk of death
Date:1/1/2013

CHICAGO In an analysis of nearly 100 studies that included approximately 3 million adults, relative to normal weight, overall obesity (combining all grades) and higher levels of obesity were both associated with a significantly higher all-cause risk of death, while overweight was associated with significantly lower all-cause mortality, according to a study in the January 2 issue of JAMA.

"Estimates of the relative mortality risks associated with normal weight, overweight, and obesity may help to inform decision making in the clinical setting," according to background information in the article.

Katherine M. Flegal, Ph.D., of the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Md., and colleagues conducted a study to compile and summarize published analyses of body mass index (BMI) and all-cause mortality that provide hazard ratios (HRs) for standard BMI categories. For the review and meta-analysis, the researchers identified 97 studies that met inclusion criteria, which provided a combined sample size of more than 2.88 million individuals and more than 270,000 deaths. Regions of origin of participants included the United States or Canada (n = 41 studies), Europe (n = 37), Australia (n = 7), China or Taiwan (n = 4), Japan (n = 2), Brazil (n = 2), Israel (n = 2), India (n = l), and Mexico (n = l).

All-cause mortality HRs for overweight (BMI of 25-<30), obesity (BMI of ≥30), grade 1 obesity (BMI of 30-<35), and grades 2 and 3 obesity (BMI of ≥35) were calculated relative to normal weight (BMI of 18.5-<25).

The researchers found that the summary HRs indicated a 6 percent lower risk of death for overweight; a 18 percent higher risk of death for obesity (all grades); a 5 percent lower risk of death for grade 1 obesity; and a 29 percent increased risk of death for grades 2 and 3 obesity.

The authors note that the finding that grade 1 obesity was not associated with higher mortality suggests that that the excess mortality in obesity may predominantly be due to elevated mortality at higher BMI levels.

The researchers add that their findings are consistent with observations of lower mortality among overweight and moderately obese patients. "Possible explanations have included earlier presentation of heavier patients, greater likelihood of receiving optimal medical treatment, cardioprotective metabolic effects of increased body fat, and benefits of higher metabolic reserves."

The use of predefined standard BMI groupings can facilitate between-study comparisons, the authors conclude.


'/>"/>

Contact: Karen Hunter
ksh7@cdc.gov
404-639-3286
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Chronic Worry Linked to Higher Risk of PTSD
2. Benefits of higher oxygen, breathing device persist after infancy
3. A New Review Reveals How “Jump Manual” Can Help People Jump Higher - Tony Nguyen
4. Daimer Debuts Carpet Cleaners For Car Dealerships Seeking Interior Auto Detailing Steam Cleaner Machines Featuring Higher Power and A Larger Water Capacity
5. Metro Atlanta ServiceMasters Team Up to Offer Higher Quality of Water Damage, Mold Removal, Carpet Cleaning and Fire Damage Services to Customers in North Georgia
6. Some Cancer Risks Higher in 9/11 Recovery Workers: Study
7. Chronic worriers at higher risk for PTSD
8. Children born prematurely are at higher risk of esophageal inflammation, cancer
9. Kids May Be at Slightly Higher Asthma Risk If Parents Had Infertility Treatments
10. Heart Drug Digoxin Tied to Higher Death Risk for Some Patients
11. Diabetes Rates Higher in Countries Using Lots of High Fructose Corn Syrup: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... 2016 , ... Jericho Project has named LaToya Williams-Belfort to the position of ... fundraising and communications for the nationally-acclaimed nonprofit, working closely with CEO Tori Lyon and ... homelessness at its roots. , “LaToya Williams-Belfort is joining Jericho at an exciting ...
(Date:5/24/2016)... ... May 24, 2016 , ... Local engineering firm, ... Virginia Medical Center located in Woodbridge, VA. The project includes a brand ... single site. , The new 2 story building houses the Central Sterile department, ...
(Date:5/24/2016)... ... May 24, 2016 , ... Regenerative Medicine is being transformed by ongoing ... therapy technology, protocols and patient results as have been achieved with Okyanos Cell ... accessible standard of care for patients worldwide. , As the Medical Advisory Chairman at ...
(Date:5/24/2016)... ... May 24, 2016 , ... Boyd Industries, a leading supplier of ... groundbreaking new product for pediatric dentistry , at AAPD 2016, the annual conference ... May 26-29. The Concealed Delivery Unit keeps dental hand pieces and other anxiety-provoking pieces ...
(Date:5/24/2016)... ... May 24, 2016 , ... Growing in popularity, more and more people ... are available and easily accessible. Whether someone chooses to cut gluten out of their ... diet, King Kullen Grocery stocks their shelves with many different gluten-free products all year ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... May 24, 2016  Joe Marziani has joined VMS BioMarketing as senior vice president ... today. In his new role, Marziani will lead the company,s business development and sales ... improve outcomes. Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
(Date:5/24/2016)... May 24, 2016 Open Access ... Clinical Neurophysiology  Elsevier , a world-leading ... services, today announced the launch of Clinical ... journal that focuses on clinical practice issues in clinical ... clinical series, normal values and didactic reviews. It is ...
(Date:5/23/2016)... 2016 Global Paclitaxel Market 2016 ... 12 companies and the Paclitaxel analysis in this study ... industry and its players. This is the ... details the current state of the industry while providing ... applications and industry chain structure. The Paclitaxel market analysis ...
Breaking Medicine Technology: