Navigation Links
Higher disease activity scores in obese RA patients
Date:6/11/2014

A new study presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) showed that obese patients with rheumatoid arthritis (RA) have higher DAS (disease activity) scores than non-obese patients, irrespective of their disease stage.1 With clinical remission as the ultimate therapeutic goal in RA,2 several studies have demonstrated that treatment to target a treatment approach guided by its impact on reducing DAS scores is more effective in lowering disease activity and, ultimately, reaching remission than usual care.3-7 Because obese patients have inflated DAS scores, treatment to target protocols may result in them being treated more aggressively than non-obese patients, which would explain the inverse relationship between body mass index (BMI)* and outcomes in RA.

"Increasing levels of body fat are associated with heightened production of proinflammatory signalling proteins and raised levels of inflammatory markers. This systemic inflammation could inflate standard DAS scores and mean that obese patients receive more aggressive treatment than their non-obese counterpart," commented Dr. Christopher Sparks, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom. "Not only do these results provide an explanation for the paradoxical relationship between BMI and disease outcome in RA, they clearly support the benefit to all RA patients of early and aggressive treatment."

RA is a chronic autoimmune disease that affects 0.3𔂿.0% of the general population; approximately one in 100 people worldwide. It is more prevalent among women than men, and more prevalent in developed countries.8 The symptoms of the disease, which include persistent inflammation, can lead to irreversible joint damage.

In this study, clinical data from an international RA database were used to identify an early (eRA, disease duration <12 months) and established (disease duration ≥12 months) RA
'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-078-801-73209
European League Against Rheumatism
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Higher-spending hospitals have fewer deaths for emergency patients
2. Taller, Heavier Women May Face Higher Ovarian Cancer Risk
3. Heart failure patients with diabetes may benefit from higher glucose levels
4. Cancer Care Costs Higher in U.S. Than Europe, But Survival Longer
5. Children Born to Obese Moms May Face Higher Autism Risk: Study
6. Could Menthol Cigarettes Pose Even Higher Stroke Risk?
7. Certain Birth Control Pills May Carry Higher Blood Clot Risk: FDA
8. Mental Illness Tied to Higher Rates of Physical Problems: Report
9. Overweight Pregnant Women at Higher Risk for Complications
10. Depression Linked to Higher Odds for Poor Leg Circulation
11. Joint-Replacement Failure Rate Higher for Smokers: Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Chemo Duck Program is pleased to announce the release of the ... with cancer. The Chemo Duck App, available on iTunes for use ... to help children of all ages living with cancer adjust to ... entertained, educated and at ease while waiting for clinic visits or ...
(Date:1/22/2015)... Angelweddingdress is a famous wedding dress company ... to follow it on Facebook, Twitter, and Pinterest. The fans ... Angelweddingdress draws a lottery every week. , Moreover, the company ... 2015. Click Angelweddingdress homepage for more information. ...
(Date:1/22/2015)... Juvent Sports ( http://www.juventsports.com ) and David Leadbetter ... to bestow a Juvent Sports Achievement award upon an ... The award commemorated and congratulated McKitrick for her record ... her first amateur tournament in 1979 and most recently ...
(Date:1/22/2015)... 22, 2015 For over 20 years, Dr. David ... and Vista area has treated just about every type of ... circumstances. And for those same twenty-plus years, the team at ... those injuries with the best possible doctor. With the ...
(Date:1/22/2015)... La Jolla, Calif. (PRWEB) January 22, 2015 ... and Assemblymembers Susan Bonilla (D-Concord) and Kristin Olsen ... (CHI) for their leadership in advancing biotechnology, biomedical ... Mitchell, Bonilla and Olsen each received the “2014 ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3
... Inc. (Nasdaq: CYNO ), a leading developer ... treatment systems, announced today that the United States District ... favorable set of rulings in a Markman hearing in ... alleges that CoolTouch,s 1320 nm CoolLipo(TM) laser system infringes ...
... to Combat Waste in Medicare ProgramsSEATTLE, March 3 ... for the Centers for Medicare & Medicaid Services (CMS), ... Care Guidelines (R). HDI will use the ... claims. HDI is the RAC for 17 Western states ...
... CORAL GABLES, Fla., March 3 Catalyst Pharmaceutical Partners, ... that acquires or in-licenses, develops and commercializes prescription drugs ... to its previously announced product development program. In ... Catalyst has decided to halt enrollment of new subjects ...
... Supported by a Grant from Otsuka America Pharmaceutical, Inc.ROCKVILLE, ... has named three universities as the recipients of Helping ... of up to $5,000 for a community mental health ... the supervision of medical faculty. The awards are ...
... chain honored for accomplishments , ... Dallas (Vocus) March 3, 2009 -- ... Alliance of Greater Cincinnati, was recently announced 2008 Contracting Professional of the ... ,Described as a pioneer in healthcare for more than three decades, Robb ...
... quality of life among obese men are related to ... gastric bypass surgery according to a new study accepted ... Clinical Endocrinology & Metabolism (JCEM). , "Previous studies ... count and can be associated with infertility, but we ...
Cached Medicine News:Health News:Cynosure Obtains Favorable Markman Rulings in Patent Infringement Case Against CoolTouch 2Health News:Cynosure Obtains Favorable Markman Rulings in Patent Infringement Case Against CoolTouch 3Health News:Recovery Audit Contractor HealthDataInsights Licenses Milliman Care Guidelines(R) 2Health News:Recovery Audit Contractor HealthDataInsights Licenses Milliman Care Guidelines(R) 3Health News:Catalyst to Focus Resources on its Lead Indication for CPP-109; Cocaine Addiction 2Health News:Catalyst to Focus Resources on its Lead Indication for CPP-109; Cocaine Addiction 3Health News:American Psychiatric Foundation Announces Recipients of Helping Hands Grants 2Health News:American Psychiatric Foundation Announces Recipients of Helping Hands Grants 3Health News:The Health Alliance's Dennis Robb Announced Contracting Professional of the Year by The Journal of Healthcare Contracting 2Health News:The Health Alliance's Dennis Robb Announced Contracting Professional of the Year by The Journal of Healthcare Contracting 3Health News:The Health Alliance's Dennis Robb Announced Contracting Professional of the Year by The Journal of Healthcare Contracting 4
(Date:1/23/2015)... 2015 A lot of discussion in the medical community ... illnesses, injuries, or conditions. As medical science advances, doctors and ... ones that they consider to be more cutting edge. Yet, ... textbook method of treatment that stands out as the best ...
(Date:1/23/2015)...  The Partnership to Fight Chronic Disease (PFCD) released a public opinion ... a new study analyzing the impact of increased cost sharing on ... working to educate policy makers and the public on the costs ... on how the Iowa healthcare exchange could ...
(Date:1/23/2015)... 23, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: NWBO )("NW ... for operable and inoperable solid tumor cancers, announced today that ... th Annual Phacilitate Immunotherapy Forum in Washington ... will take place on January 26 at 10:30 a.m. EST ...
Breaking Medicine Technology:No One-Size-Fits-All Remedy for Hernia Correction 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3
... WESTLAKE VILLAGE, Calif., Dec. 21 Specialists On ... its 10,000th emergency teleneurology consultation since the company,s inception. ... expands SOC,s leadership position as the largest private emergency ... consults when it recently responded to a neurologic emergency ...
... , SAN MARINO, Calif., Dec. 21 /PRNewswire-FirstCall/ -- ... announced that it filed an updated Information Statement including ... September 30, 2009, as well as year-end statements for ... in PDF form free of charge via the ...
Cached Medicine Technology:Specialists On Call Delivers 10,000th Emergency Teleneurology Consultation 2Specialists On Call Delivers 10,000th Emergency Teleneurology Consultation 3Viral Genetics Files 2009 3rd Quarter Consolidated Financials and Information Statement at Pinksheets.com 2
... Operation: , Standby: All toggle switches at off ... pulse/s); 10 s (1 pulses/10 s) , Tetanus: ... pulses/s) , Train-Of-Four: Single (4 pulses/2 s); repeat ... Output Current: Adjustable from 0-70 mA(HI range) 0-6.0mA ...
... of Operation: , Double Burst : 2 60-ms bursts ... 1 s (1 pulse/s) , Tetanus: 50 Hz ... Train-Of-Four: Single (4 pulses/2 s) , Output Current: Adjustable ... Monophasic pulses (200-us duration) , Indicators: Battery LED (green) ...
... Modes of Operation: , Standby: A standby ... stimulus pulses. , Twitch: 1 s (1 pulse/s) ... Train-Of-Four: Single (4 pulses/2 s) , Output Current: ... Square Wave Monophasic pulses (200-us duration) , Indicators: ...
Anesthesia Associates Model 100 Compact Peripheral Nerve Stimulator, incorporates the latest state-of-the-art electronics with solid state cicuitry to ensure trouble-free operation and extended batte...
Medicine Products: