Navigation Links
High-salt diet and ulcer bug combine to increase risk of cancer
Date:4/18/2013

Numerous epidemiologic studies have shown that a diet high in salt is associated with an increased risk of gastric cancer. Now Timothy L. Cover and colleagues of Vanderbilt University show that high dietary salt combined with infection by the ulcer-causing bacterium Helicobacter pylori greatly increases the risk of cancer. The study was published ahead of print in the journal Infection and Immunity.

In the study, the researchers infected Mongolian gerbils with H. pylori. One set of gerbils received a regular diet; the other, a high salt diet. At the end of the experiment the researchers analyzed the animals' stomach tissues. Every animal on the high salt diet developed cancer, compared with just 58 percent of those on the regular diet.

It appears development of gastric cancer required the presence of a particular bacterial oncoprotein, known as CagA, which is produced by H. pylori. Gastric cancer did not develop in animals on the high salt diet that were infected with a mutant H. pylori which did not produce CagA. In earlier studies, Cover and others had shown that culturing H. pylori in a high salt environment boosts production of CagA. "This was one of the driving forces that led us to undertake the current studies," says Cover.

The investigators note that while no studies, to their knowledge, have examined relationships among a high salt diet, and infection with H. pylori expressing cagA, "in several parts of the world that have high rates of gastric cancer, there is a high prevalence of cagA+ strains and a large proportion of the population consumes a high-salt diet."

The investigators also detected significantly higher levels of gastric inflammation in H. pylori-infected gerbils on a high salt diet than in those on a regular diet, a finding which Cover says is relevant to many types of cancer. They also showed that transcription of various inflammatory cytokines,
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Other stomach microbiota modulate resistance to H. pylori-driven ulcers
2. Zion Health Announces Release of New Line of Home Remedies: Kanwa Whole Body Detox teas for Stomach Pain, Ulcers, and Skin Allergies Now available at Bee Health E in Doug
3. Pressure Ulcer Treatment and Prevention Cushions Designed by EHOB Now Offered by Rehabmart.com
4. Stroke drug kills bacteria that cause ulcers and tuberculosis
5. Foot Ulcers Tied to Increased Death Risk for People With Diabetes
6. New Pill Appears Effective, Safe for Ulcerative Colitis: Study
7. NYU School of Medicine announces new clinical trial for ulcerative colitis
8. Spray-on Skin May Someday Heal Stubborn Leg Ulcers
9. Gastric feeding tubes may raise pressure ulcer risk
10. Spencer Institute Lifestyle Fitness Coach Certification Combines Life Coaching and Fitness Coaching in One Powerful Online Training
11. Asbestos exposure, asbestosis, and smoking combined greatly increase lung cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... CA (PRWEB) August 28, 2014 ... small and mid-sized healthcare organizations, today announced that it ... online appointment company ZocDoc , to head their ... company has created a sales management position. , “I’m ... startup like DoctorBase that already has so much traction ...
(Date:8/28/2014)... Tea Leaves Health is pleased ... leader in Connected Consumer Management. By integrating Gigya’s ... the opportunity to build more authentic relationships with ... and how they like to interact. , Gigya’s ... brands to understand and connect with mobile and ...
(Date:8/28/2014)... Hanover, MA (PRWEB) August 28, 2014 Now ... a run/walk that was started in 2011 by two brain ... to raise much needed awareness, provide education to help increase ... have been impacted by a brain aneurysm. We hope that ... support a worthy cause at the 4th Annual Step for ...
(Date:8/28/2014)... Texas (PRWEB) August 28, 2014 MMAR ... The program is a chance for regular customers to ... Medical without the need for a wholesale license. It’s ... coaches, semi-professional athletic programs and others who regularly purchase ... , “Whether supporting your own active lifestyle or ...
(Date:8/28/2014)... The revenue cycle process touches on ... time a patient books an appointment with a physician’s ... payments for services rendered to the healthcare provider. ... has the RCM process down to a science. Over ... common place in nearly every healthcare facility around the ...
Breaking Medicine News(10 mins):Health News:DoctorBase Hires Josh Angeles as Vice-President of Sales 2Health News:Tea Leaves Health Begins Important New Partnership with Gigya 2Health News:Tea Leaves Health Begins Important New Partnership with Gigya 3Health News:Step for Hope and Raise Brain Aneurysm Awareness 2Health News:MMAR Medical Announces Customer Membership Program 2Health News:Tips on Automating the Revenue Cycle Process with Medical Billing 2Health News:Tips on Automating the Revenue Cycle Process with Medical Billing 3
... & plc (NYSE/LSE: CCL; NYSE CUK) today announced a ... majority of which will be incurred in the second ... to cruise itineraries for the six-week period ended June ... Control (CDC) recommendation against non-essential travel to Mexico. The ...
... The National Autism Association (NAA) announced today ... agencies for Project Lifesaver Equipment through the organization,s FOUND ... County Utah Sheriff,s Department will both receive grants for ... children with autism at high risk for wandering. FOUND ...
... Lialda(R) (mesalamine) or Pentasa(R) (mesalamine) for the Treatment of ... May 18 Shire plc (LSE: SHP, Nasdaq: ... responding to the needs of patients who are diagnosed ... from Shire by expanding its Patient Assistant Program (PAP). ...
... EventBOSTON, May 18 AMR Research , ... and its supporting technologies, today announced the final agenda for ... The Phoenician Resort in Scottsdale, Arizona, May 27-29, 2009. ... of Walt Disney Companies from 1984-2005, and the release of ...
... says , , MONDAY, May 18 (HealthDay News) -- A new ... patients moist and clear, researchers say. , Using a special ... too quickly, which is a common problem for people with ... of the airway causes their airways to dry, and allows ...
... no more dangerous than regular flu , , MONDAY, May 18 ... City public school died Sunday night of complications from the ... States to die from the disease that was first identified ... death was not surprising, because even a normal flu season ...
Cached Medicine News:Health News:Carnival Corporation & plc Reports Financial Impact of Itinerary Changes Responding to H1N1 Influenza Mexico Travel Advisory; Plans Rapid Return to Popular Mexican Ports 2Health News:National Autism Association Provides Funds to Law Enforcement Agencies in Staunton, Virginia and Summit County, Utah for Project Lifesaver Equipment 2Health News:Shire Expands Gastrointestinal Patient Assistance Program for Uninsured or Unemployed Americans 2Health News:Shire Expands Gastrointestinal Patient Assistance Program for Uninsured or Unemployed Americans 3Health News:Shire Expands Gastrointestinal Patient Assistance Program for Uninsured or Unemployed Americans 4Health News:Shire Expands Gastrointestinal Patient Assistance Program for Uninsured or Unemployed Americans 5Health News:AMR Research Announces Final Agenda for Sold-Out Supply Chain Executive Conference 2Health News:New Spray Could Benefit Cystic Fibrosis Patients 2Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 2Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 3Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 4Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 5Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 6Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 7Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 8Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 9Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 10Health News:NYC School Assistant Principal Is Latest Swine Flu Fatality 11
(Date:8/27/2014)... , Aug. 27, 2014 Reportlinker.com announces that ... catalogue: Baby Food Eastern Europe 2014 ... Food Eastern Europe 2014" is a new report by ... in Eastern Europe , key segments, ... This report also examines trends which are currently affecting ...
(Date:8/27/2014)... YORK , Aug. 27, 2014 ... new market research report is available ... Chinese Guidebook for Application and Approval ... Regulations to Practices (2014 Edition) ... Now, Chinese regulations ...
(Date:8/27/2014)... and NINGBO, China , Aug. 27, ... Menovo Pharmaceutical Co., Ltd, ("Menovo") today announced they had ... generic pharmaceuticals, primarily targeting the United States ... Amerigen and Menovo will jointly develop products for Amerigen ... . Menovo will be responsible for manufacturing API and ...
Breaking Medicine Technology:Baby Food Eastern Europe 2014 2Baby Food Eastern Europe 2014 3Baby Food Eastern Europe 2014 4Baby Food Eastern Europe 2014 5Baby Food Eastern Europe 2014 6Baby Food Eastern Europe 2014 7Baby Food Eastern Europe 2014 8Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 2Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 3Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 4Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 5Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 6Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 7Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 8Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 9Latest Chinese Guidebook for Application and Approval of Imported Medical Device Registration: From Regulations to Practices (2014 Edition) 10Amerigen Pharmaceuticals Limited and the Ningbo Menovo Pharmaceutical Co., Ltd, today announced they had entered into a collaboration agreement regarding the development of generic pharmaceuticals, primarily targeting the United States market 2
Digital Ultrasonic Diagnostic Imaging System...
Quantitative Plasma-based Factor XIII Incorporation Assay Kit...
Pefakit PiCT LMWH Controls...
Calcium Chloride 0.020M - 4 ml...
Medicine Products: