Navigation Links
High-salt diet and ulcer bug combine to increase risk of cancer
Date:4/18/2013

Numerous epidemiologic studies have shown that a diet high in salt is associated with an increased risk of gastric cancer. Now Timothy L. Cover and colleagues of Vanderbilt University show that high dietary salt combined with infection by the ulcer-causing bacterium Helicobacter pylori greatly increases the risk of cancer. The study was published ahead of print in the journal Infection and Immunity.

In the study, the researchers infected Mongolian gerbils with H. pylori. One set of gerbils received a regular diet; the other, a high salt diet. At the end of the experiment the researchers analyzed the animals' stomach tissues. Every animal on the high salt diet developed cancer, compared with just 58 percent of those on the regular diet.

It appears development of gastric cancer required the presence of a particular bacterial oncoprotein, known as CagA, which is produced by H. pylori. Gastric cancer did not develop in animals on the high salt diet that were infected with a mutant H. pylori which did not produce CagA. In earlier studies, Cover and others had shown that culturing H. pylori in a high salt environment boosts production of CagA. "This was one of the driving forces that led us to undertake the current studies," says Cover.

The investigators note that while no studies, to their knowledge, have examined relationships among a high salt diet, and infection with H. pylori expressing cagA, "in several parts of the world that have high rates of gastric cancer, there is a high prevalence of cagA+ strains and a large proportion of the population consumes a high-salt diet."

The investigators also detected significantly higher levels of gastric inflammation in H. pylori-infected gerbils on a high salt diet than in those on a regular diet, a finding which Cover says is relevant to many types of cancer. They also showed that transcription of various inflammatory cytokines,
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Other stomach microbiota modulate resistance to H. pylori-driven ulcers
2. Zion Health Announces Release of New Line of Home Remedies: Kanwa Whole Body Detox teas for Stomach Pain, Ulcers, and Skin Allergies Now available at Bee Health E in Doug
3. Pressure Ulcer Treatment and Prevention Cushions Designed by EHOB Now Offered by Rehabmart.com
4. Stroke drug kills bacteria that cause ulcers and tuberculosis
5. Foot Ulcers Tied to Increased Death Risk for People With Diabetes
6. New Pill Appears Effective, Safe for Ulcerative Colitis: Study
7. NYU School of Medicine announces new clinical trial for ulcerative colitis
8. Spray-on Skin May Someday Heal Stubborn Leg Ulcers
9. Gastric feeding tubes may raise pressure ulcer risk
10. Spencer Institute Lifestyle Fitness Coach Certification Combines Life Coaching and Fitness Coaching in One Powerful Online Training
11. Asbestos exposure, asbestosis, and smoking combined greatly increase lung cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... (PRWEB) October 30, 2014 Dr. Joseph Furlin ... new website for his practices; OB GYN in Melrose ... . This website contains important information about each of ... well as downloadable patient forms in English and Spanish. ... the service pages on the website provide Dr. Furlin’s patients ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Global prebiotics ... 2020, according to a new study by Grand View ... surging demand for sugar and fat free products owing ... the demand for prebiotics over the forecast period. , ... , Food & beverage was the largest application ...
(Date:10/30/2014)... 30, 2014 REV'D Provision Co. announced ... available through a unique service called, The Feed ... empower the everyday athlete. The Feed has taken the ... created a system to pass that information on to ... is now available on The Feed!” says REV’D® marketing ...
(Date:10/30/2014)... York (PRWEB) October 30, 2014 The ... (NAMS) came to a close on Saturday, October ... since the Society’s inception in 1989. NAMS is North ... and quality of life of all women during midlife ... aging. With over 2,000 physicians and thought leaders from ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Sound Telecom, a ... infographic that will assist people any time they wonder, “Should ... the right answer by leading them through a series of ... to their initial query. , There are many considerations and ... to use an answering service . This decision infographic ...
Breaking Medicine News(10 mins):Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 2Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 3Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 4Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 5Health News:Nutrition Experts at TheFeed.com Get REV'D 2Health News:Nutrition Experts at TheFeed.com Get REV'D 3Health News:Highlights from The North American Menopause Society 25th Annual Meeting 2Health News:Highlights from The North American Menopause Society 25th Annual Meeting 3Health News:Sound Telecom Produces Decision Infographic to Aid Businesses 2
... ... at least one broken implant within 11 years. Smart Choice MRI offers the ... the first MRI clinic in Milwaukee to offer a silicone implant rupture screening ... to a 75% savings when compared to other MRI providers. , ...
... ... Dispensing System™ at ASCP as one option for addressing health reform’s new medication waste ... ... has surpassed 500 customers of its world-class software and proven hardware components to enhance ...
... mice, researchers found , WEDNESDAY, May 26 (HealthDay News) ... certain industrial chemicals while pregnant are at an increased ... animal study suggests. , The chemicals -- bisphenol-A (BPA) ... manufacturing purposes, and are known for interfering with hormonal ...
... 11 Thursday 15 July 2010, Stockholm, Sweden, Stockholm ... Excess body weight is a major risk factor for ... cancer, making obesity one of the leading preventable causes ... the most significant public health challenges of the 21st ...
... BEER-SHEVA, ISRAEL, May 26, 2010 -- A new study ... of the Negev (BGU) indicates that advanced age does ... that older drivers are more sensitive to potential hazards ... Hazard Perception," suggests that driving experience improves drivers, awareness ...
... In the May issue of Mayo Clinic ... pain management in cirrhotic patients. The physician experts reviewed ... no limits in the search to recommend a uniform ... patients. Cirrhosis is a substantial public health problem, ...
Cached Medicine News:Health News:Affordable Implant Screening: Protect Against "Silent" Ruptures 2Health News:Talyst Reaches Major Milestone: 500 Implementations in Long-Term Care, Acute Care and Corrections 2Health News:Talyst Reaches Major Milestone: 500 Implementations in Long-Term Care, Acute Care and Corrections 3Health News:Prenatal Exposure to Chemicals Linked to Breast Cancer Risk 2Health News:Media arrangements for the International Congress on Obesity 2Health News:Elderly drivers' ability to detect hazards doesn't degrade with age according to Ben-Gurion U. 2Health News:Mayo Clinic Proceedings: Review of pain management practices for cirrhosis patients 2
(Date:10/30/2014)... -- WuXi PharmaTech (Cayman) Inc. (NYSE: WX ), ... serving the pharmaceutical, biotechnology, and medical device industries, with ... the United States , today announced the ... Tel Aviv area of Israel.  ... of integrated R&D services to local customers. It will ...
(Date:10/30/2014)... 30, 2014   ViaDerma, Inc. (OTCQB: ... new products to market, has recently released a ... is a topical liquid tetracycline-based antibiotic that uses ... convert oral medication active ingredients into topical drugs. ... aid antibiotic to help prevent skin infection in ...
(Date:10/30/2014)... 2014 Molecular Profiles Ltd., a subsidiary of ... Maryland -based Xceleron have announced a ... clinical development that will be launched at AAPS in ... This partnership extends Molecular Profiles, new ROADMAP to ... this month. The company also has complementary collaborations in ...
Breaking Medicine Technology:WuXi AppTec Launches Representative Office in Israel, Forms Strategic Collaboration with Pontifax 2ViaDerma, Inc. Lead Product TetraStem Shown Effective in Fighting Staph Infections including MRSA 2ViaDerma, Inc. Lead Product TetraStem Shown Effective in Fighting Staph Infections including MRSA 3Molecular Profiles To Launch US Strategic Alliance At AAPS 2Molecular Profiles To Launch US Strategic Alliance At AAPS 3
... CINCINNATI, April 11, 2011 HealthWarehouse.com, Inc. (OTC: ... announced Consumer Reports found it to have among ... Lipitor, Nexium, Plavix, and Singulair. The ... rating pharmacies for price, accuracy, knowledge, and speed. ...
... TechniScan,s (OTC BB: TSNI) novel breast ultrasound technology ... Institute of Ultrasound Medicine,s annual conference in New York ... session on advanced breast ultrasound imaging, Michael Andre, Ph.D., ... of California, San Diego Moores Cancer Center that enlists ...
Cached Medicine Technology:Consumer Reports Finds HealthWarehouse.com Has Lowest Total Price for Lipitor, Nexium, Plavix, and Singulair 2TechniScan's Breast Imaging Science Featured at National Ultrasound Conference 2TechniScan's Breast Imaging Science Featured at National Ultrasound Conference 3
Preference Toric quarterly planned replacement lenses are durable, easy to handle and virtually maintenance free. Meeting the needs of those suffering from astigmatism, these soft contact lenses are ...
... fit for all astigmatic patients. Ideal ... who require excellent visual acuity and ... of disposable lenses; astigmatic spectacle wearers ... lenses; and spherically masked astigmatic patients ...
C 2.3K with lightweight headband: the practical alternative for spectacle-wearers. Delivered in protective designer case....
... Vitrasert implant is a device ... with Aids-related Cytomegalovirus (CMV) Retinitis. This ... CMV when compared with conventional intravenous ... embedded in a polymer-based system that ...
Medicine Products: