Navigation Links
High-risk prostate cancer associated with significantly lower bone mineral content loss
Date:7/13/2010

Men with prostate cancer lose significantly less bone mineral content (BMC) as they age than men who are free of the disease, according to research in the July issue of BJUI. The findings are important because loss of BMC can play a key role in the development of fragile bones, fractures and osteoporosis.

American researchers studied 519 participants who joined the Baltimore Longitudinal Study at an average age of 56 between 1973 and 1984. The maximum follow-up was 35 years and the median was 22 years. Seventy-six men who took part in the study were later diagnosed with prostate cancer, with just under a quarter (24 per cent) falling into the high-risk category.

When they charted the individual BMCs of the study subjects over an extended period, the researchers could clearly see that the decline was much larger in healthy men than in men later diagnosed with prostate cancer, especially those with high-risk prostate cancer. This occurred despite the fact that the initial baseline readings were very similar for all three groups.

The researchers also adjusted the figures to take account of other factors that affect BMC, such as smoking status, body mass index, dietary calcium and vitamin D. However, this did not change the significant differences between the healthy men and those with prostate cancer.

"There are numerous possible mechanisms to explain the relationship between prostate cancer and BMC" says lead author Dr Stacy Loeb, from Johns Hopkins University, Maryland, USA.

"It is well known that prostate cancer frequently metastasizes (spreads) to bone. Although the biology underlying the association between BMC and this form of cancer requires additional research, our findings suggest that common growth factors might be involved in both bone maintenance and the progression of prostate cancer.

"We believe that this may be why the patients with the highest risk prostate cancer also demonstrated th
'/>"/>

Contact: Annette Whibley
wizard.media@virgin.net
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. School-Based Efforts May Help Curb Obesity in High-Risk Kids
2. Surveillance colonoscopy should be targeted to high-risk patients
3. Indeterminate breast lesions found in high-risk patients should be evaluated aggressively to exclude malignancy
4. Selecting high-risk patients for heart screening
5. Drug reduces risk of prostate cancer diagnosis in high-risk men
6. New heart valve replacement technologies offer hope for high-risk patients
7. Mammogram Plus MRI Cost-Effective in High-Risk Women
8. Mammogram Plus MRI Seems Cost-Effective in High-Risk Women
9. Combined mammography and breast MRI useful for some high-risk women
10. UT researcher receives $2.4 million to research obesity, high-risk pregnancy
11. How prostate cancer packs a punch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... -- Both drinking and getting drunk at an early ... high school students, a new study suggests. The ... who drink, could help expand alcohol-prevention efforts aimed at ... them from becoming binge drinkers, the researchers suggested. , ... use and progression to first heavy use as risk ...
(Date:9/23/2014)... Francisco, CA (PRWEB) September 23, 2014 Avid ... for original 1967 The Doors Eagle Auditorium Seattle concert posters. ... their album “Break On Through” that year. The Seattle Eagles ... to Hawley, “The Doors would return to Eagles Auditorium in ... July poster is not known and comes in three colors. ...
(Date:9/23/2014)... Grinnell Mutual seeks submissions from the ... Midwest. Working Together Making It Better will provide ... projects positively impacting their communities. , “So many ... communities a better places,” said Grinnell Mutual ... Baker. “Their leadership—as coaches, as volunteers, as mentors—help ...
(Date:9/23/2014)... 2014 (HealthDay News) -- Few children who ... behavioral therapy, and the rates vary six-fold across ... finds. Medication alone can manage symptoms for ... if they also receive behavioral therapy (psychotherapy), the ... data in more than 1,500 counties across the ...
(Date:9/23/2014)... recent Oregon survey about an exercise DVD that adds ... of elementary school students found it had a high ... offered clear advantages for overly sedentary educational programs. , ... by the Healthy Youth Program of the Linus Pauling ... , Brain Breaks leads children in 5-7 minute segments ...
Breaking Medicine News(10 mins):Health News:Younger Age at First Drink, Higher Odds for Problem Drinking: Study 2Health News:Younger Age at First Drink, Higher Odds for Problem Drinking: Study 3Health News:Grinnell Mutual Invites Submissions for Innovative, Collaborative Local Projects in Its Second Annual Working Together Making It Better Promotion 2Health News:Kids Taking ADHD Drugs Get Little Psychotherapy: Study 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 3
... Residents Access to Nursing Home, Assisted Living, Home ... Zip Code Statewide RICHMOND, Va., April 30 The cost ... is rising at a rate outpacing inflation, putting significant financial ... annual study by Genworth Financial. At the same time, ...
... Home, Assisted Living, Home Care and Adult Day Health Care ... The cost of long term ... putting significant financial pressure on those in or near retirement, ... the same time, the current economic downturn has led to ...
... Tissue density tied to chances of disease in middle-age and ... Breast cancer risk assessment and prevention should start much earlier ... examined breast cancer risk factors in young women. , ... their mothers found that breast tissue composition in young women ...
... diagnosed in U.S. have continued to be mild, officials ... World Health Organization on Wednesday raised the swine flu ... pandemic is imminent, and urged countries to implement their ... world health officials that the outbreak could trigger large ...
... Study Gives North Dakotans Access to Nursing Home, Assisted Living, ... Every Zip Code StatewideRICHMOND, Va., April 30 The cost ... a rate outpacing inflation, putting significant financial pressure on those ... Genworth Financial. At the same time, the current economic ...
... Study Gives New Mexico Residents Access to Nursing ... Costs in Nearly Every Zip Code Statewide RICHMOND, Va., April ... in New Mexico is rising at a rate outpacing inflation, ... according to an annual study by Genworth Financial. At ...
Cached Medicine News:Health News:Growth in Washington Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 2Health News:Growth in Washington Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 3Health News:Growth in Washington Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 4Health News:Growth in Texas Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 2Health News:Growth in Texas Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 3Health News:Growth in Texas Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 4Health News:Young Women's Breast Tissue Offers Clues to Cancer Risk 2Health News:WHO Raises Swine Flu Alert 2Health News:WHO Raises Swine Flu Alert 3Health News:WHO Raises Swine Flu Alert 4Health News:WHO Raises Swine Flu Alert 5Health News:WHO Raises Swine Flu Alert 6Health News:Growth in North Dakota Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 2Health News:Growth in North Dakota Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 3Health News:Growth in North Dakota Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 4Health News:Growth in New Mexico Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 2Health News:Growth in New Mexico Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 3Health News:Growth in New Mexico Long Term Care Costs Outpacing the Rate of Inflation, According to Annual Genworth Financial Study 4
(Date:9/23/2014)... Nuclear medicine market is estimated to ... Nuclear are drugs that contain radionuclide-emitting ionization radiation, ... and treat diseases. Increasing incidences of ... and ready availability of radiopharmaceuticals are the major ... awareness and use of SPECT and PET also ...
(Date:9/23/2014)...   LabStyle Innovations Corp . (OTCQB: DRIO), ... announced that it has closed a $4.2 million ... stock and warrants.  No placement agent was used ... expects to secure net proceeds of approximately $4.1 ... intends to use the net proceeds from the ...
(Date:9/23/2014)... YORK , September 23, 2014 /PRNewswire/ ... solution Face2Gene améliorée lors d,une série de ... ), pionnier dans le domaine de l,analyse ... sa solution au stand n° 1035 lors de ... San Diego , en ...
Breaking Medicine Technology:Global Nuclear Medicine Market - Growth, Trends & Forecasts (2014-2019) 2LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 2LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 3LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 4LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 5FDNA exposera sa solution Face2Gene intégrée en ligne avec London Medical Databases (LMD) à l'ASHG 2014 2FDNA exposera sa solution Face2Gene intégrée en ligne avec London Medical Databases (LMD) à l'ASHG 2014 3
... Potential of microRNAs as,Novel Cancer Drug Targets, REHOVOT, ... 2007,/PRNewswire-FirstCall/ -- Rosetta Genomics Ltd , a leading ... Cell by scientists from the Weizmann Institute of ... potential for a,specific, single microRNA (miR-34a) to be ...
... endpoint achieved -- , LAINATE, Italy - July ... positive preliminary results from its,phase II/III study with ... a broad spectrum, semi-synthetic,antibiotic that is not absorbed ... Cosmo's MMX(tm) technology, which delivers the active,ingredient into ...
Cached Medicine Technology:Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 2Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 3Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 4Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 5Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III,Data with Rifamycin MMX in Infectious Diarrhea 2
... Temporary, Transvenous Pacing Lead System Features an ... lubricated guide catheter. The system is designed ... The system is disposable, for temporary single ... of 7 days or less. The lead ...
Automated slide maker and stainer...
... The new ... an electromagnetic braking ... years of reliable ... whisper-quiet operation. The ...
The Schiller treadmill ergometer is designed for stress tests, sports medicine and cardiology. It is equipped and tested with the latest safety system and has been manufactured under the stringent qu...
Medicine Products: