Navigation Links
High potency statins linked to better outcome following a heart attack
Date:2/20/2014

A study looking at the data of thousands of patients who suffered heart attacks has suggested treatment with high-potency statins offers a significantly improved chance of survival compared to those taking normal statins.

The study, led by the University of Dundee, also found a combination of statins and the drug ezetimibe showed no improved survival rate, although researchers caution this finding needs further testing.

"There is presently a lot of interest in ezetimibe as a potential treatment for heart patients," said Professor Chim Lang, from the Division of Cardiovascular and Diabetes Medicine at the University of Dundee Medical School.

"Ezetimibe has been shown to be very effective at lowering cholesterol but we do not know its effect on survival. The key question really is whether it is better than statins, especially high potency statins such as rosuvastatin or atorvastatin.

"What our study has showed, looking at the data from thousands of patients in the UK, is that patients who switched from normal statin treatment to high potency statins lived longer.

"Those who had ezetimibe added did not appear to have a better outcome. So for the moment the data supports the use of high potency statins, one of which, atorvastatin, is now off patent and is cheap and effective."

Results of the study have been published online in the journal Heart.

Data for the study was drawn from the UK's Clinical Practice Research Datalink. Researchers looked at the data for patients who had survived 30 days after their first heart attack, who had not received prior statin or ezetimibe therapy, and who were started on a statin within that period of their attack.

The data of 9597 patients was used. 6990 of those were treated with simvastatin, 1883 had switched to a more potent statin, and 724 were given an ezetimibe/statin combination.

Data for the group was analysed for an average 3.2 years from the start point of their first heart attack. During that time there were 1134 deaths.

The results showed that patients who switched to a high-potency statin had a 28% lower risk of death compared to those who received simvastatin. There was no observed benefit of adding ezetimibe.


'/>"/>

Contact: Roddy Isles
r.isles@dundee.ac.uk
44-138-238-4910
University of Dundee
Source:Eurekalert

Related medicine news :

1. Sleep affects potency of vaccines
2. High-Potency Pot in Pregnancy May Cause Brain Damage
3. ReNew Life Launches Norwegian Gold EPA 1000 Omega, the Highest Potency EPA-only Fish Oil Supplement Sold in Health Food Stores
4. Ganetespib shows potency against ALK-positive lung cancer and overcomes crizotinib resistance
5. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces Prescription hCG Drops with Equal Potency to hCG Injections
6. ReNew Life, America’s #1 Probiotic Brand, Introduces a High-Potency Probiotic Uniquely Formulated for Women
7. ReNew Life, America’s #1 Probiotic Brand, Introduces a High-Potency Probiotic Uniquely Formulated for Women
8. Is There a Dark Side to High Potency Calcium? Source Naturals MBP Bone Renew Helps Consumers Avoid Potential Risks
9. Statins prevent cancer in heart transplant recipients
10. Statins May Help Prevent Enlarged Prostate: Study
11. Are Statins Less Helpful for Women?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... 2016 , ... Itopia, a leader in cloud services automation ... Platform (CIP) into Cielo®, a discovery, migration and cloud orchestration engine. This integration ... and medium business (SMB) clients. , In recent years, BI and ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Jones Agency, a family owned insurance company ... launching a cooperative charity drive with the Tarrant Area Food Bank in the hopes ... and families in need, the Tarrant County Food Bank offers hope and security to ...
(Date:2/12/2016)... ... 2016 , ... Donor Network West, the organ procurement organization that heals lives ... San Ramon Regional Medical Center. Under the collaboration, the first of its kind, specific ... a more certain time frame for donor families for the recovery of organs. ...
(Date:2/12/2016)... ... February 12, 2016 , ... Mediaplanet today announces ... The print component of “Revolutionizing Cancer Care” is distributed within the February 12 ... Seattle, with a circulation of approximately 250,000 copies and an estimated readership of ...
(Date:2/12/2016)... , ... February 12, 2016 , ... US Sport Camps ... Iowa. Legacy Golf Club, located in Norwalk, serves as the host site and directing ... Rob Randall. , “We have had successful camps in recent years around Des Moines ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... --  HeartWare International, Inc . (NASDAQ: HTWR ) ... its financial results for the three and 12 months ... at 8:00 a.m. ET.  The company plans to release ... webcast.  On the conference call and webcast, management will ... quarter and business outlook.   --> ...
(Date:2/12/2016)... Texas , Feb. 12, 2016 On ... for Robotic Surgery at St. David,s North Austin Medical ... da Vinci ® Xi ® Surgical System ... 7000dV. Thiru Lakshman , M.D., colorectal ... a total proctocolectomy utilizing Integrated Table Motion technology, which ...
(Date:2/12/2016)... WILMINGTON, North Carolina , 12 februari ... Laboratories, Inc. (AAI/CML), een toonaangevende leverancier van ... farmaceutische en biotechnologische industrieën, kondigt vandaag een ... en mogelijkheden op haar locatie in ... in vraag heeft geleid tot meerdere recente ...
Breaking Medicine Technology: