Navigation Links
High pollution linked to poor lung function growth in children in Mexico City
Date:8/15/2007

Children who are chronically exposed to higher levels of air pollution show marked deficiencies in lung growth and function, and not just short-term breathing problems, according to researchers in Mexico.

"Our study revealed significant deficits in lung function growth in children with long-term exposure to air pollutants, wrote Isabelle Romieu, M.D., M.P.H., lead author of the study. "In addition to the important impact of lung health, early lung deficits may increase the risk of developing chronic obstructive lung disease later in life, as well as cardiovascular morbidity and general mortality.

These conclusions are the result of a three-year, multi-site prospective study that measured lung function growth in 3,170 eight-year-old children at 39 schools in Mexico City and analyzed it with respect to the childrens exposure to common urban pollutants: ozone (O3), nitrogen dioxide (NO2), and particulate matter under 10 m (PM10).

Dr. Romieu, of the Instituto Nacional de Salud Publico in Mexico, and eight colleagues reported their findings in the second issue for August of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Previous studies have found that short-term exposure to pollutants is associated with acute but reversible deficits in lung function, but the effects of long-term exposure, like that experienced by residents of heavily polluted urban environments, had not been conclusively characterized.

The researchers analyzed forced vital capacity in one second (FVC1); forced expiratory flow, midexpiratory phase (FEF25-75); and forced expiratory volume in one second (FEV1) in the schoolchildren at six month increments over three years to determine the effects of pollutant exposure, which was measured by air monitoring stations within 2 km of the children's schools. They conducted personal exposure assessments on 60 randomly selected children in the study to ensure that the air monitoring station data was an accurate representation of individual exposure.

Although all measurements of lung function increased over time, the researchers found that higher exposure to O3, NO2 and PM10 was significantly associated with growth deficits in FVC and FEV1.

At the beginning of the study and at each phase of follow-up, children exposed to lower O3 and PM10 concentrations had better lung function values that children exposed to higher concentrations, wrote the researchers.

Strikingly, the effect of pollutant exposure on FEV1 among the children in their study was slighter greater than the effect of exposure to maternal smoking among children in the United States.

The study could not determine the mechanism by which pollutants change lung growth, but other studies have found differences in lung morphology related to O3 exposure, and suggested that chronic exposure to PM and O3 may be associated with small airway disease.

Recently, oxidative stress from oxidant compounds, including O3, NO2 and PM has been identified as a potential cause of an inflammatory response, which could then lead to chronic lung damage. The reversibility of the damage is unclear, but the authors note that previous studies have reported long-term deficits in lung function associated with air pollutants.

Although we could not identify specific sources [of the pollutants], the effect is likely to be due to vehicular exhaust, wrote the researchers, concluding that there is a clear need for stricter air pollution measures in Mexico City to protect lung growth in children living there.


'/>"/>
Contact: Suzy Martin
smartin@thoracic.org
212-315-8631
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Air pollution affects the heart
2. Pollution could be a risk
3. Pollution- hazardous for diabetics
4. Air Pollution Found To Accelerate Heart Disease
5. Air pollution may raise risk of lung cancer
6. Air pollution hits heart patients during exercise
7. Air Pollution and Heart Attacks
8. Air pollution combined with greater medical needs
9. Traffic pollution linked to severe asthma attacks
10. Air Pollution Tied to Stroke Risk
11. Air Pollution said To Increase Risk of Cardiovascular Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Carolina (PRWEB) , ... June 26, 2016 , ... ... of a new product that was developed to enhance the health of felines. The ... centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial ... Plant City Observer , brings up a new, often overlooked aspect of head lice: the ... closing for fumigation is not a common occurrence, but a necessary one in the event ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... ... ... Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair ... hour by 2020 and then adjusting it yearly to increase at the same rate as ... the wage floor does not erode again, and make future increases more predictable. , The ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)... MOUNTAIN VIEW, Calif. , June 23, 2016 ... 9:00 a.m. CST on Thursday, July 7, 2016 , , ... kayla.belcher@frost.com ) , , , , EXPERT PANELISTS:  ... Sciences, Nitin Naik; Senior Industry Analyst, Christi Bird; Senior Industry Analyst, ... The global pharmaceutical industry is witnessing ...
(Date:6/23/2016)... , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate ... in Latin America . ... ... ... ...
Breaking Medicine Technology: