Navigation Links
High insulin levels raise risk of breast cancer in postmenopausal women
Date:1/9/2009

the researchers assessed their fasting insulin level, naturally occurring levels of estradiol (a form of estrogen), and body mass index, or BMI (a measure of obesity). After dividing the women into four groups based on their fasting insulin levels and controlling for estrogen levels, the researchers found that women with the highest insulin levels were nearly 50 percent more likely to have developed breast cancer compared with women who had the lowest insulin levels.

Most of this effect was observed in the large subset of women from the WHI study who did not use hormone-replacement therapy. HRT has a strong effect on insulin and other hormonal factors, so eliminating this variable gives a clearer picture of insulin's effect on breast cancer. "Among these women, the influence of insulin on breast cancer risk was quite high," says lead author Marc Gunter, Ph.D., assistant professor of epidemiology & population health at Einstein. "Women with the highest insulin levels in their blood were more than two times more likely to develop breast cancer than women with the lowest insulin levels." Moreover, "when we controlled for insulin, the association between obesity and breast cancer became much weaker," adds Dr. Gunter. "This means that a large component of that obesity-cancer relationship may be mediated by insulin levels."

The findings have important implications for prevention, and possibly treatment, of postmenopausal breast cancer, according to Howard Strickler, M.D., M.P.H, who was senior author of the paper and a professor of epidemiology & population health at Einstein. "Research now needs to focus on ways to reduce insulin's effects on cell growth and replication in the breast while preserving its positive metabolic effects.

There are several possibilities and working with our laboratory collaborators we hope to make fast progress," said Dr. Strickler.

"It is also possible that screening non-diabetic postmenopausal women
'/>"/>

Contact: Michael Heller
mheller@aecom.yu.edu
718-430-4186
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. High Insulin May Boost Odds of Breast Cancer
2. Vitamin K Slows Insulin Resistance in Older Men
3. Vitamin K linked to insulin resistance in older men
4. Lilly Announces Major Donation of Insulin to International Diabetes Federations Life for a Child Program; Initial Focus Will Be on Sub-Saharan Africa
5. Completely novel action of insulin unveiled
6. Impact of insulin pump under study
7. Diabetes Spectrum Reports a Study Assessing the i-port(R) Injection Port for Administration of Insulin
8. Pancreatic Cells Turned Into Insulin-Producing Beta Cells
9. New survey explores the impact of insulin injections on people with diabetes
10. Inheritance of hormonal disorder marked by excessive insulin in daughters
11. Montreal researchers prove that insulin-producing cells can give rise to stem-like cells in-vitro
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... New York, NY (PRWEB) October 20, 2014 ... to be introduced in the U.S., has a lot to ... time when our country recognizes the achievements and contributions of ... marks the anniversary for Punzoné, and today it shares its ... and take a trip to Italy - even if it ...
(Date:10/20/2014)... Maryland, USA (PRWEB) October 20, 2014 ... to track interventions? Here comes a wonderful app Metassessor ... mobile app development company helped its client “Intervention ... more efficiently. The app is designed for iOS 4.3 ... iPod touch. This app is optimized for iPhone 5. ...
(Date:10/19/2014)... October 20, 2014 The leading ... ( http://www.top10bestseohosting.com/go/iPage/ ) and GreenGeeks are the best ... platforms for those who want to buy high ... time. , The IT manager of Top10BestSEOHosting.com says, ... most recommended suppliers for everyone. A lot of ...
(Date:10/19/2014)... 19, 2014 Dr. Babatunde Osotimehin, Executive ... news of a ceasefire agreement that is expected to ... girls who were kidnapped from the north-eastern Nigerian town ... captivity long enough, and it is high time they ... Dr. Osotimehin. , "We owe it to these girls ...
(Date:10/19/2014)... Having been working in the garment industry for decades, ... According to James, one of the company’s top designers, many ... high-low skirts that add beauty to them. Chiffon floor length ... unveiled its new selection of 2014 long prom dresses. ... items are available in over 20 popular designs. The company ...
Breaking Medicine News(10 mins):Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 3Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 4Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 2Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 3Health News:Top10BestSEOHosting.com Considers iPage And GreenGeeks As The Best Dedicated Server Hosting Suppliers 2Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2
... Rochelle, NY -- The current issue of Medical ... Liebert, Inc., explores how the U.S. military is incorporating ... military personnel serving in the war zones and the ... issue is available online at http://www.liebertpub.com/acu . ...
... 4, 2012 As the pharmaceutical industry continues to ... protecting patients from counterfeit medicines, as well as the ... mounted. In an effort to encourage comprehensive public standards ... is proposing a set of recommended best practices that ...
... used extensively in Chinese traditional medicine that kill ... the leading causes of tooth loss in children and adults. ... , they say that these substances could have a role ... Stefan Gafner and colleagues explain that the dried root ...
... Weight loss surgery is not a cure for type 2 ... a new study published in the British Journal of ... to 80 per cent of diabetes patients have been cured ... that only 41 per cent of patients achieve remission using ...
... -- Arrogant people are less likely than humble people to ... Although personal factors (such as previous time commitments and ... how many people are watching) come into play, humility is ... helping hand, according to the study published online Jan. 2 ...
... a study that investigates the challenges of disseminating clinical research ... have found that fewer than half of a sample of ... Health (NIH) were published within 30 months of completing the ... issue of the British Medical Journal , which focuses ...
Cached Medicine News:Health News:Proposed standard offers best practices to help ensure pharmaceutical supply chain integrity 2Health News:Proposed standard offers best practices to help ensure pharmaceutical supply chain integrity 3Health News:Proposed standard offers best practices to help ensure pharmaceutical supply chain integrity 4Health News:Scientists reassess weight loss surgery for type 2 diabetes 2Health News:Need Help? Seek Out the Humble 2Health News:Many NIH-funded clinical trials go unpublished over 2 years after completion 2
(Date:10/17/2014)... 17, 2014  Training market researchers to spot ... factor in today,s highly competitive global marketplace. As ... that effectively and efficiently produce high performing analysts, ... Effective training programs can help ... from internal clients by developing analysts who can ...
(Date:10/17/2014)... UBM Medica US announces that Neurology Times ... for neurologists and other healthcare providers, features special coverage on ... discussions of the latest developments in approaches to diagnosis. ... , more than the total of those who have multiple ... can be difficult because there are no confirmatory medical tests. ...
(Date:10/17/2014)... According to the ... (Optical Coherence Tomography, Hyperspectral Imaging, Photoacoustic Tomography), Product ... Oncology, Cardiology) - Global Forecasts to 2019" ... Imaging market over the forecast period of ... million in 2014 and is expected to ...
Breaking Medicine Technology:Effective Training Programs for Market Research Groups can Boost Overall Organizational Success 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 3Optical Imaging Market Worth $1,669.2 Million by 2019 2Optical Imaging Market Worth $1,669.2 Million by 2019 3Optical Imaging Market Worth $1,669.2 Million by 2019 4
... Wound Management division of Smith & Nephew (LSE: SN; NYSE: ... on a range of products and therapies from their ALLEVYN ... wound care portfolio. The data demonstrate advanced healing strategies and ... Results of the studies are being presented at the Clinical ...
... 2011 Cardica, Inc. (Nasdaq: CRDC ... System will be featured in a clinical presentation ... Carolina Heart Institute-International Society for Minimally Invasive Cardiothoracic ... presentation, entitled "Robotic Coronary Revascularization: Connectors and Pearls," ...
Cached Medicine Technology:Smith & Nephew Showcases Strong Data at the Clinical Symposium on Advances in Skin & Wound Care Conference 2Smith & Nephew Showcases Strong Data at the Clinical Symposium on Advances in Skin & Wound Care Conference 3Smith & Nephew Showcases Strong Data at the Clinical Symposium on Advances in Skin & Wound Care Conference 4Cardica's Cardiac Anastomosis Device Featured in Clinical Presentation on Robotic Cardiac Bypass Procedures 2Cardica's Cardiac Anastomosis Device Featured in Clinical Presentation on Robotic Cardiac Bypass Procedures 3
The CGIL iridectomy contact glass was designed by Riquin, Fankhauser et al. to perform full thickness peripheral laser iridectomies....
The CGVL vitrectomy contact glass was designed by Rol, Fankhauser et al. for photodisruptive YAG laser procedures in the posterior vitreous....
For newly born children 10 mm internal diameter of the cornea part. Designed to work with argon/YAG Lasers....
... uses a classical distance-independent measuring principle which ... The size of the mire image is ... and the measured object; 2. The resulting ... the Ophthalmometer and the measured object; 3. ...
Medicine Products: