Navigation Links
High-energy ultrasound sharpens view of liver tumors

DURHAM, N.C. -- A high-energy form of ultrasound imaging developed by researchers at Duke University's Pratt School of Engineering produces pictures of liver tumors that are better than those made with traditional ultrasound, according to results of a clinical study.

The study suggests that the imaging method known as Acoustic Radiation Force Impulse (ARFI) ultrasound might offer a new tool for screening patients at increased risk for liver cancers, according to the researchers. They say it might also play a useful role in guiding biopsy procedures and minimally invasive therapies aimed at destroying cancerous tissues found deep in the abdomen.

The researchers reported their findings Jan. 7 in the journal Physics in Medicine and Biology. The work was funded by the National Institutes of Health with system support from Siemens Medical Solutions.

First developed six years ago by Duke biomedical engineers Gregg Trahey and Kathy Nightingale, ARFI uses high-energy sound waves to push on tissues like sonic fingers. A tracking beam then captures the movement of the tissue, providing a measure of its elasticity or stiffness.

"To our knowledge, these are the first images of abdominal malignancies in humans that show tissue elasticity," said Trahey, professor of biomedical engineering, radiology and medical physics at Duke. The preliminary findings, which represent the Ph.D. thesis work of Trahey's former graduate student Brian Fahey, have already led Siemens to pursue a product prototype that will combine traditional ultrasound with ARFI, he added.

In general, primary liver cancers are soft while those that have spread from other organs are hard. ARFI may be able to tell the difference between hard and soft tumors, Trahey said. "If borne out in further studies, [that discriminating ability] suggests that ARFI may be useful in guiding treatment decisions."

"All current imaging methodsincluding CT, MRI and ultrasoundhave mediocre performance in the detection of early liver cancers," he added. "There is a potential role for ARFI because it is low cost and can be built on conventional ultrasound machines."

Traditional ultrasound is now the guidance method of choice in many hospitals for procedures targeting the liver, kidneys, pancreas and lymph nodes, Trahey said. Ultrasound has advantages in that it is widely available, low cost and doesn't expose patients to ionizing radiation. However, a significant number of tumors are difficult to see with this method, requiring physicians to resort to alternatives such as CT and MRI, which add to the complexity and cost.

In the new study, the researchers captured ARFI images of 12 tumors in nine patients, including seven liver and two kidney tumors, and compared them to traditional ultrasound. The ARFI pictures showed greater contrast than standard ultrasound, providing clearer definition of the edges of cancerous masses.


Contact: Kendall Morgan
Duke University

Related medicine news :

1. ZONARE Ranked Best in KLAS as Hand Carried Ultrasound Vendor in 2007 Top20: Year-End Report
2. Breast Cancer Imaging Study Indicates Breast-Specific Gamma Imaging (BSGI) Is a Strong Adjunct Imaging Modality to Mammography and Ultrasound
3. AIUM and ACEP publish guidelines for performing emergency trauma ultrasound -- the FAST exam
4. Procedure to detect fetal heart defects is first automated use of 3-D ultrasound
5. Ultrasound Treats Localized Prostate Cancer
6. ZONARE Surpasses 1000th Worldwide Ultrasound System Shipment
7. Through-Wave Ultrasound: Effective, Economical and Ideal for Breast Imaging, Biopsy
8. Ultrasound Beats Blood Test for Gauging Ovarian Cancers: Study
9. Ultrasound-guided injections help ease chronic Achilles tendon pain
10. Transcutaneous cervical esophageal ultrasound can not substitute for 24-h pH monitoring or manometry
11. Aloka to Unveil New ProSound Diagnostic Ultrasound System at the 17th World Congress on Ultrasound in Obstetrics and Gynecology, 7th to 11th of October 2007 in Florence, Italy
Post Your Comments:
(Date:11/30/2015)... Maryland (PRWEB) , ... November 30, 2015 , ... ... interactions could be of critical importance to the medical schools of the future. ... exhibited its healthcare suite at the 2015 ChangeMedEd conference in Chicago, organized by ...
(Date:11/30/2015)... ... 30, 2015 , ... TransPack Volume 6 features 30 customizable transitions created exclusively ... transitions to wipes with blur & drop shadow options. Utilize the controls in ... one clip to the next with TransPack's easily customizable styles. , TransPack ...
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... healthcare professionals worldwide today released the results of a survey of educational needs ... and Africa found a growing global demand for high quality online and face-to-face ...
(Date:11/30/2015)... , ... November 30, 2015 ... ... to announce their strategic partnership at the Radiological Society of North America ... Winscribe, global providers of cutting-edge dictation and speech-enabled documentation software, announced their ...
(Date:11/30/2015)... ... November 30, 2015 , ... Several significant coding-related changes are ... likely to include new codes for spine and hip X-rays, paravertebral facet blocks ... of code changes in musculoskeletal, radiology and nervous system sections on an Orthopedic ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... NEW YORK , November 27, 2015 ... health system is set to go online. The potential ... and processes is vast and far from fully exploited ... access to patient health records, either via mobile tablet ... ) --> ) ...
(Date:11/27/2015)... , Nov. 27, 2015 Research and ... the "Global Intrauterine Devices Market 2015-2019" report ... --> In this report, the author the ... devices market for 2015-2019. To calculate the market size, ... following type of products: Hormonal IUDs and copper IUDs. ...
(Date:11/26/2015)... Países Bajos, November 26, 2015 ... fotodinámica de Bremachlorin para el cáncer avanzado.   ... con la terapia fotodinámica de Bremachlorin para el cáncer ... enfoque combina la inmunoterapia con la terapia fotodinámica de ... Clinical Cancer Research . --> Clinical Cancer ...
Breaking Medicine Technology: