Navigation Links
High doses of 'load' slows loss of bone in spinal cord injury
Date:2/16/2012

Loss of bone density leads to brittle bones that fracture easily. It is a major complication of spinal cord injury (SCI), which affects about 250,000 Americans every year.

A new clinical trial conducted by University of Iowa researchers shows that delivering high doses of "load," or stress, to bone through programmed electrical stimulation of the muscle significantly slows the loss of bone density in patients with SCI.

The focus on quantifying the effective dose of load is one of the study's most important aspects, says Richard Shields, P.T., Ph.D., a professor and director of the UI Physical Therapy and Rehabilitation Science Graduate Programs. The study also is the first to carefully test the impact of different doses of load in humans with paralysis.

Previous research had suggested that stressing or loading bone through muscle contractions could slow the loss of bone density, but results from clinical trials have been mixed.

"Thirty years ago a clinical trial concluded that putting patients with SCI in an upright weight-bearing position with braces or standing frames did nothing to prevent loss of bone density," Shields says. "The novelty of our study is we have designed a method for individuals with paralysis to stand (bear weight) while superimposing a dose of muscle force using programmed electrical stimulation of the muscle."

The study findings, published in the journal Osteoporosis International in December 2011, reveal that only high "doses" of muscle force are effective for significantly reducing bone loss.

"The previous studies, without muscle activation, were like doing a drug trial where the dose of drug was too low, or below 'therapeutic threshold,' to cause an effect," Shields explains.

The UI researchers have also recently shown that the electrical stimulation strengthens muscle by activating genes that promote muscle growth and endurance, and improve glucose metabolism.'/>"/>

Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-356-7124
University of Iowa Health Care
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. ASTRO publishes supplement on protecting cancer patients by reducing radiation doses, side effects
2. Children with food allergies should carry 2 doses of emergency medicine
3. Botox reduces wrinkles even in less frequent doses
4. High doses of antioxidant supplements induce stem cell genetic abnormalities
5. Organic Clothing – Is Your Clothing Delivering Death in Small Doses?
6. Cumulative Radiation Doses Seen in Cardiac Imaging
7. High doses of ursodeoxycholic acid ineffective for NASH patients
8. Higher Statin Doses Linked to Fewer Heart Attacks, Stroke
9. Yale researchers find double doses of chicken pox vaccine most effective
10. Study confirms 2 vaccine doses protect children from chickenpox
11. Preparing Small Doses of Medication From Syringes Called Risky
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
High doses of 'load' slows loss of bone in spinal cord injury
(Date:8/28/2015)... ... ... Dr. Gregory K. Toumayan, D.C., Q.M.E., is now treating patients with back ... hip pain, neck pain, stiffness, muscle spasms, and numbness. , Dr. Toumayan received ... went on to earn his title of Doctor of Chiropractic from the Palmer College ...
(Date:8/28/2015)... ... August 28, 2015 , ... Northridge dentists Dr. Elyson ... For just $199, patients can currently receive a one hour treatment of this teeth ... but it includes a number of unique features that can turn teeth up to ...
(Date:8/28/2015)... La Mirada, Ca (PRWEB) , ... August 28, ... ... are now administering medical evaluations for those seeking to go deep sea diving. ... pressure, possible oxygen toxicity, and decompression sickness; for these reasons, it is vital ...
(Date:8/28/2015)... Washington, DC (PRWEB) , ... ... ... Atlantic Information Services, Inc.’s (AIS) Medicare-Medicaid Dual Eligibles Database have added comprehensive ... newest CMS-backed alignment demonstration approved for a December 2015 launch; and Idaho’s ...
(Date:8/28/2015)... ... ... External Counterpulsation, also known as ECP or EECP, is a proven treatment ... ECP) machines with a full clinic licence to help people prevent and reverse heart ... prevent and reverse heart disease through its evidence-based integrative approach to heart ...
Breaking Medicine News(10 mins):Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 3Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2Health News:Healthpointe Now Offering Scuba Physicals 2Health News:AIS Duals Database: August Update Finds Two New Duals Programs in Rhode Island and Idaho 2Health News:Buy New External Counterpulsation (EECP or ECP) With Heart Fit Clinic 2
... research center focused,on improving the quality of life of ... Chattanooga, led by a world-renowned researcher whose,concepts and tools ... The Siskin Center for Child and Family Research ... nonprofit organization focused,on education, outreach and support for children ...
... DIEGO, Dec. 3 Cardium Therapeutics,(Amex: ... presenting a webcast providing,an investor presentation, corporate update ... The webcast will be presented following the ... and can be accessed at, http://www.investorcalendar.com/IC/CEPage.asp?ID=138418 at ...
... place objects in the wound, researchers say , , ... disorder where people wound themselves and then place ... among American teens, especially girls, researchers say. , ... Radiological Society of North America,s annual meeting in ...
... 3 NewCardio, Inc.,(OTC Bulletin Board: NWCI) a cardiac ... a restructure of the going-forward terms of,its December 27, ... investors,in the transaction have exercised a portion of their ... sheet. This will extend the,Company,s cash reserves to ...
... of New York State,s Metro Services has chosen BRANDEMiX, the NYC-based ... brand and launch an employee communications campaign in support of their ... ... December 3, 2008 -- The Cerebral Palsy Associations of New York ...
... their family and friends put their feet where their mouths were on ... charity in the inaugural HBA Great Australian Run. , ... Melbourne, VIC ... employees and their family and friends put their feet where their mouths ...
Cached Medicine News:Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 2Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 3Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 4Health News:Cardium Announces Investor Presentation and Corporate Update Webcast 2Health News:'Self-Embedding' a Troubling Trend Among Teens 2Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 2Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 3Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 4Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 5Health News:NewCardio Restructures 2007 Financing, Receives $2.8 Million Additional Cash and Improves Capital Structure 6Health News:BRANDEMiX Selected to Launch Cerebral Palsy Associations of NYS Metro Services New Strategic Plan 2Health News:HBA People Walk the Talk for Better Health in the HBA Great Australian Run 2
(Date:8/28/2015)... , Aug. 28, 2015 ... has announced the addition of the "Investigation ... to their offering. Developed by Pharmacia ... prostaglandin receptor agonist which effectively reduces intraocular pressure. ... FDA, latanoprost (under the trade name of Xalatan) ...
(Date:8/28/2015)... -- Perrigo Company plc ("Perrigo") (NYSE: PRGO ; ... MYL ) shareholder vote regarding its planned unsolicited ... Mylan,s offer to Perrigo shareholders have always been, and ... reflection of the value available to Perrigo shareholders, and ... has allowed its shareholders to consider," said Joseph ...
(Date:8/28/2015)... 28, 2015 , Joint research by ... from Biostar , Published in ,Stem Cells Translational ... lifespan through multiple IV administration of Adipose-derived MSC ... expectancy found , Commercialization within 5 years expected ... possibility that adult mesenchymal stem cells (MSCs) may extend ...
Breaking Medicine Technology:China Latanoprost Market Investigation Report 2015-2019 2Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 2Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 3Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 4Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 5Korean Researchers Find the Possibility that Adult Mesenchymal Stem Cells (MSCs) May Extend Lifespan 2
... The Astellas European Foundation is delighted to announce the winner ... of the University of Geneva, Switzerland Last evening, ... of US$ 300,000 to support work on their project entitled ... liver transplantation for hepatocellular carcinoma , at the Astellas European ...
... 2011 Unilife Corporation ("Unilife" or "Company") (NASDAQ: UNIS, ASX: ... will be presenting at two upcoming investor conferences taking place ... Mr. Shortall will present at the Rodman and Renshaw Annual ... On Wednesday, September 14, Mr. Shortall will present ...
Cached Medicine Technology:The Astellas European Foundation Winner of Transplantation Grant 2011 Announced 2Unilife to Participate in Two Investor Conferences 2
...
...
EDM Lumbar Drainage Kit with and without Bioglide are fabricated of radiopaque (barium impregnated) silicone tubing, and are packaged with stainless steel stylets inserted in the lumen....
Lumbar External Drainage System (LED) with Touhy needle is indicated for temporary access to the Lumbar Subarachnoid region as a means of draining cerebral spinal fluid (CSF) in order to reduce incre...
Medicine Products: