Navigation Links
High circulating D-dimers are associated with presence of ascites
Date:4/30/2008

The liver is the production site of most of the proteins which favour and inhibit the process of coagulation and fibrinolysis. Patients with liver cirrhosis may develop serious coagulopathy and a hyperfibrinolytic state, which contributes to the bleeding tendency. Plasma levels of fragment D-dimer (D-dimer) represent an accurate marker of fibrinolytic activity. The finding of a high plasma D-dimer concentration in patients with liver cirrhosis, decompensated with ascites, led Agarwal et al. to suggest the major role of ascites in the pathogenesis of the hyperfibrinolytic state associated with liver failure.

This study, published in the March 14, 2008, issue of the World Journal of Gastroenterology, shows that high circulating D-dimer levels are associated with the presence of ascites, and these decrease or return to normal following its resolution. The depletion of ascitic fluid might prevent bleeding complications, especially if invasive procedures become necessary. Interestingly enough, in the absence of ascites, high D-dimer levels are associated with the presence of hepatocellular carcinoma (HCC). HCC is a frequent complication of liver cirrhosis and its detection at an early stage is important. The finding of high plasma D-dimer levels in cirrhotic patients without ascites may represent a marker of HCC.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
0086-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Circulating fats kill transplanted pancreas cells, study shows
2. FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients
3. New study shows promise in reducing surgical risks associated with surgical bleeding
4. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
5. Study, meta-analysis examine factors associated with death from heatstroke
6. Increased distance to physician associated with thicker skin cancer at diagnosis
7. Minorities more likely to have sleep durations associated with increased mortality
8. Income inequality associated with overnourishment and undernourishment in India
9. Maternal depression and controlling behavior associated with increased stress response in infants
10. Nurses describe dedication, frustration associated with their jobs
11. New research shows ACTOS is associated with a 38 percent lower risk of heart attack
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... ... 2016 , ... The Justin Veatch Fund announced Thursday that ... film Whispering Spirits and its discussion guide for use by all of ... in the war against teen drug abuse. NCADD is the oldest anti-addiction advocacy ...
(Date:12/9/2016)... ... December 09, 2016 , ... MEDI+SIGN®, a provider of fully-automated ... new solution for Emergency Departments (ED) has been added to their portfolio. Housed ... examination rooms, and with a simplified pallet of information available to the patient, ...
(Date:12/8/2016)... , ... December 08, 2016 , ... ... Research Institute (WCRI) officially opened registration today for its 33rd Annual Issues ... Boston, MA . , The theme of the conference is “Persistent Challenges and ...
(Date:12/8/2016)... ... 08, 2016 , ... CURE Media Group, the nation’s leading digital and print ... Upstage Lung Cancer in efforts to combat lung cancer, announced CURE Media Group President ... “CURE Media Group is honored to team up with Upstage Lung Cancer in order ...
(Date:12/8/2016)... ... 08, 2016 , ... Launching of the ... Instance Manager architecture, meeting the needs of multichannel growth and doubling the ... auto-dialing system without agents, Presence Robodialer, provides greater operational capacity, administrative flexibility ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... 2016 Australia Glaucoma Surgery Devices Market ... report, "Australia Glaucoma Surgery Devices Market Outlook to ... Glaucoma Surgery Devices market. The report provides value, ... and average prices (USD) within market segement - ... company shares and distribution shares data for each ...
(Date:12/8/2016)... global biosurgery market is expected to grow at a ... to 2021. The market is poised to reach USD ... 2016. The market is primarily driven by rising number ... spinal problems, increasing clearance of biosurgery products by regulatory ... In this report, the biosurgery market is ...
(Date:12/8/2016)... Dec. 8, 2016 KEY FINDINGS ... grow in 2017-2023. Various reasons for growth of the ... higher incidences of chronic diseases, high recovery cost of ... services. Medical lifting sling refers to an assistive ... mobility. These slings connect to the lift and hold ...
Breaking Medicine Technology: