Navigation Links
High blood sugar levels in older women linked to colorectal cancer
Date:11/29/2011

BRONX, NY -- Elevated blood sugar levels are associated with an increased risk of colorectal cancer, according to a study led by researchers at Albert Einstein College of Medicine of Yeshiva University. The findings, observed in nearly 5,000 postmenopausal women, appear in the Nov. 29 online edition of the British Journal of Cancer.

According to the American Cancer Society, colorectal cancer is the third most commonly diagnosed cancer and the third leading cause of cancer death in both men and women in the U.S.

Statistics compiled by the U.S. Centers for Disease Control and Prevention for 2007 (the most recent year for which figures are available) show that 142,672 Americans were diagnosed with colorectal cancer, including 69,917 women; the 53,219 deaths from colorectal cancer that year were divided almost equally between men and women.

The Einstein study involved women who were enrolled in the National Institutes of Health's landmark Women's Health Initiative study. For these women, fasting blood sugar and insulin levels had been measured at baseline (i.e., the start of the study) and then several more times over the next 12 years.

By the end of the 12-year period, 81 of the women had developed colorectal cancer. The researchers found that elevated baseline glucose levels were associated with increased colorectal cancer riskand that women in the highest third of baseline glucose levels were nearly twice as likely to have developed colorectal cancer as women in the lowest third of blood glucose levels. Results were similar when the scientists looked at repeated glucose measurements over time. No association was found between insulin levels and risk for colorectal cancer.

Obesityusually accompanied by elevated blood levels of insulin and glucoseis a known risk factor for colorectal cancer. Researchers have long suspected that obesity's influence on colorectal cancer risk stems from the elevated insulin levels it causes. But the Einstein study suggests that obesity's impact on this cancer may be due to elevated glucose levels, or to some factor correlated with elevated glucose levels.

"The next challenge is to find the mechanism by which chronically elevated blood glucose levels may lead to colorectal cancer," said Geoffrey Kabat, Ph.D., a senior epidemiologist at Einstein and lead author of the paper. Its possible that elevated glucose levels are linked to increased blood levels of growth factors and inflammatory factors that spur the growth of intestinal polyps, some of which later develop into cancer.


'/>"/>

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Related medicine news :

1. Cell molecule identified as central player in the formation of new blood vessels
2. Newer Blood Thinner May Pose Danger to Trauma Patients
3. Life-threatening condition in preemies linked to blood type
4. At-Home Blood Pressure Readings Might Help Track Ailing Brain: Study
5. Molecules on branched-polymer surfaces can capture rare tumor cells in blood
6. Blood Type May Be Associated With Stroke Risk: Study
7. New screening method can detect a range of clinical conditions from a single dried blood spot
8. Blood disorders are a public health issue
9. Engineered, drug-secreting blood vessels reverse anemia in mice
10. Blood-based genomic test better than imaging test for ruling out obstructive coronary artery disease
11. Got High Blood Pressure? Kiwi Fruit May Help
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/26/2017)... Barcelona, Spain (PRWEB) , ... September 26, 2017 ... ... exciting nutritional ingredient that is not only entirely new and different, it is ... extracts, announced today that the company has received an exclusive license agreement with ...
(Date:9/26/2017)... ... September 26, 2017 , ... Data Integrity: , The ... **, Dec. 5-6, 2017 – Arlington, VA, http://www.fdanews.com/fdadataintegrity , ... indicate the firm’s electronic records may not be trustworthy and reliable … a more ...
(Date:9/26/2017)... ... September 26, 2017 , ... The 2017 American Academy ... “The Magic of Fat,” revealed not only the latest about cosmetic procedures to remove ... an evolution in cosmetic medicine. , “Fat really is magical, especially when it comes ...
(Date:9/26/2017)... ... ... “Good Morning Sunshine!: Finding Strength and Comfort in God”: a hopeful and ... Comfort in God” is the creation of published author, Terri Braun, a mother of ... at a local mental health center for over twenty years, helping the severely and ...
(Date:9/26/2017)... ... September 26, 2017 , ... “Sonflower Submission”: a relatable and concise reality ... destinations of negativity, complaining and the need to always be correct. There comes a ... for a lesson in stress-less living to be learned. “Sonflower Submission” is the ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... PROVIDENCE, R.I. , Sept. 25, 2017 /PRNewswire/ ... immunogenicity assessment, vaccine design, and immune-engineering today announced ... focused on the development of personalized therapeutic cancer ... and has provided exclusive access to enabling technologies ... MSc Eng., MBA will lead EpiVax Oncology as ...
(Date:9/22/2017)... Md. , Sept. 22, 2017  As the ... Republican Senators Bill Cassidy (R-LA) and ... Information notes that the medical device industry is in ... medical device tax, the 2.3% excise tax on medical ... But they also want covered patients, increased visits and ...
(Date:9/19/2017)... Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that uses ... today:   ... Jim ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has led R&D and business ...
Breaking Medicine Technology: