Navigation Links
High-Fat Meal May Trigger Asthma

Study finds fatty foods lead to inflammation, reduced lung function

SUNDAY, May 16 (HealthDay News) -- It's well known that food laden with fat isn't good for your heart, but now a new study suggests that fatty meals may affect lung function, too.

Australian researchers tested people with asthma before and after a high-fat meal or after a low-fat meal, and found that the high-fat meal increased inflammation and reduced lung function.

"This is the first study to look at the effects of a high-fat challenge on airway inflammation. Our preliminary results demonstrate that at four hours after the consumption of the food challenges, subjects who consumed the high-fat meal had an increase in airway inflammation. They also had an impaired response to [asthma medication]," said the study's lead author, Lisa Wood, a lecturer in biomedical sciences and pharmacy at the Hunter Medical Research Institute in New Lambton.

"If these results can be confirmed by further research, this suggests that strategies aimed at reducing dietary fat intake may be useful in managing asthma," Wood added.

The prevalence of asthma has increased significantly over the past few decades, and one factor that's been implicated in that rise is the typically high-fat Western diet. Dietary fat can activate an immune response and cause inflammation throughout the body, but the specific effects in the airway hadn't been previously studied, according to Wood.

Thirty non-obese people with asthma were recruited for the study, as well as 16 obese adults. The non-obese volunteers were randomly selected to receive either a high-fat or low-fat meal. The obese study participants were all given the high-fat meal.

The high-fat meal consisted of fast-food hamburgers and hash browns. The meal contained about 1,000 calories, including 60 grams of fat. That means about 50 percent of the meal came from fat. A normal meal should contain no more than 25 percent to 35 percent of its calories from fat, according to recommendations from the American Heart Association.

The low-fat meal contained a low-fat yogurt. That meal was 200 calories and contained 13 percent fat.

Sputum samples were collected at the start of the study and four hours after the meal. In addition, lung function was tested at both of those times.

The researchers found that markers of airway inflammation increased significantly among those who ate the high-fat meal. They also found that lung function was affected as well. And people who were given the high-fat meal who then used their asthma inhaler medication saw just a 1 percent improvement in their lung function. Those on the low-fat meal saw a 4.5 percent increase in their lung function after using their medication.

"Further work is needed to understand the clinical relevance of these observations. Nonetheless, a difference of 3 to 4 percent [in lung function] is approaching a level which can be perceived by patients," said Wood.

Wood said the researchers don't know exactly why the body seems to respond to a high-fat meal this way, but said the immune system might be recognizing saturated fat as an invading pathogen, which prompts inflammation.

She also said the researchers don't yet know how long these effects might last, but added that if someone is consuming high-fat foods every day, they may be experiencing these effects for at least several hours a day.

Dr. Thomas Leath, division director of allergy and immunology at Scott & White Healthcare in Round Rock, Texas, said, "I wouldn't have thought that the food itself would cause the inflammation. Eating that way can lead to obesity, and fat cells can definitely cause quite a bit of inflammation, but I'm surprised one meal could do this."

Leath said he doubted that the effect on lung function was significant enough for people to notice, but said the study definitely provides "one more reason that people shouldn't eat high-calorie, high-fat diets."

Wood is scheduled to present the results of her study Sunday at the American Thoracic Society's International Conference in New Orleans.

More information

Learn more about asthma triggers from the Nemours Foundation's KidsHealth Web site.

SOURCES: Lisa Wood, Ph.D., lecturer in biomedical sciences and pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton, Australia; Thomas Leath, M.D., assistant professor of pediatrics, department of allergy and immunology, Texas A&M Health Science Center, College Station, Texas, and division director, allergy and immunology, Scott & White Healthcare, Round Rock, Texas; May 16, 2010, presentation, American Thoracic Society International Conference, New Orleans

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. High-fat ketogenic diet to control seizures is safe over long term
2. Wooden Toilet Seats Can Trigger Childrens Rash
3. Lack of cellular enzyme triggers switch in glucose processing
4. Puberty May Trigger Sleep Apnea in Overweight Kids
5. Stress triggers tumor formation, Yale researchers find
6. Blue Cross Claim That 39% Premium Hikes Due Only to Escalating Cost of Health Care Trigger Calls for Regulation of Rates
7. Small Time Company Rolls into the Big League: Trigger Point Performance Therapy Selected to Attend Athletes' Performance NFL Combine Preparation Program
8. Stress hormone, depression trigger obesity in girls
9. Discovery of cellular switch may provide new means of triggering cell death, treating disease
10. Measles Outbreak Triggered by Unvaccinated Child
11. Movies Trigger Young Adult Smokers to Light Up
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... ... The directory is specialized and only includes chiropractic clinics in the US. , ... and trustworthy alternative health practitioner when back pain sets in. When people are ...
(Date:11/30/2015)... ... ... On Saturday, October 24th, 2015, at the Mill Race Park in Downtown ... walk known as “Making Strides Against Breast Cancer”. Patients and staff members from A ... Battle Creek, joined in for this campaign that sought to raise donations that will ...
(Date:11/30/2015)... ... 30, 2015 , ... Rick Sommer, president of Intellitec Solutions, ... of Information Systems course. Based in Wilmington Delaware, Intellitec Solutions is an established ... student in the Enterprise Resource Planning (ERP) Systems class. The course focuses on ...
(Date:11/30/2015)... ... November 30, 2015 , ... RoamRight, a leading provider of ... Public Television’s Travel With Kids to promote family vacations around the world. ... they explore international destinations and educate families about the people and places of the ...
(Date:11/30/2015)... NJ (PRWEB) , ... November 30, 2015 , ... ... top choice for innovative, patient centered orthopedic care. Led by John Vitolo, ... your injury or chronic condition, the team at Advocare Orthopedic & Sports Medicine ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... MOUNTAIN VIEW, Calif. , Nov. 30, ... has been the norm in U.S. medical ... obsolete. The increasingly popular accountable care payer-provider ... payment models and, in their wake, alter ... or quality-based payments will push forward new ...
(Date:11/30/2015)... 2015 Cumberland Pharmaceuticals (CPIX), today announced that A.J. ... on December 3, 2015. TIME: 3:15p.m. ET LINK: ... LINK: --> DATE: Thursday, ... --> --> This ... invited to ask the company questions in real-time - both ...
(Date:11/30/2015)... Varian Medical Systems (NYSE: VAR ) has signed ... Apollo Hospitals Group, the largest hospital chain in India ... technologists in the country. The MoU was signed by Dr. ... Ashok Kakkar , Varian,s India managing director, ... , Varian intends to deploy its Access to Care program ...
Breaking Medicine Technology: