Navigation Links
High-Fat Diet While Pregnant May Produce Obese Kids
Date:11/14/2008

It may lead to permanent changes in the fetal brain, study says

FRIDAY, Nov. 14 (HealthDay News) -- Eating a high-fat diet during pregnancy causes permanent changes in the fetal brain that can result in overeating and obesity early in life, according to a study with rats.

The researchers from Rockefeller University in New York City said their finding is an important advance in understanding mechanisms of fetal programming. It also sheds light on the production of new brain cells, helping to explain the dramatic rise of childhood obesity in the United States over the past three decades.

"We've shown that short-term exposure to a high-fat diet in utero produces permanent neurons in the fetal brain that later increase the appetite for fat," study senior author Sarah F. Leibowitz, director of the Laboratory of Behavioral Neurobiology at Rockefeller, said in a university news release. "This work provides the first evidence for a fetal program that links high levels of fat circulating in the mother's blood during pregnancy to the overeating and increased weight gain of offspring after weaning."

For the study, pregnant rats were fed either a high-fat or a balanced diet for two weeks. Pups born to mothers that ate the high-fat diet ate more, weighed more throughout life, and began puberty earlier than pups born to mothers that ate a balanced diet. The pups born to the mothers that at the high-fat diet also had higher levels of triglycerides in the blood at birth and as adults, and also had greater production of brain peptides that stimulate eating and weight gain.

The study was published in the Nov. 12 issue of the Journal of Neuroscience.

The creation of neurons that increase the appetite for fat may also occur in human babies born to mothers who eat a high-fat diet during pregnancy, Leibowitz said.

"We're programming our children to be fat," she believes. "I think it's very clear that there's vulnerability in the developing brain, and we've identified the site of this action where new neurons are being born. We now need to understand how the lipids affect these precursor cells that form these fat-sensitive neurons that live with us throughout life."

More information

The Nemours Foundation has more about overweight and obesity in children.



-- Robert Preidt



SOURCE: Rockefeller University, news release, Nov. 11, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. A high-fat diet could promote the development of Alzheimers
2. High-Fat Diet Can Disrupt Bodys Clock
3. High-fat diet makes mice susceptible to liver injury
4. US Oncology Applauds Senator Baucuss Healthcare Reform Call to Action for 2009, Supports Collaborative Measures to Enhance Cancer Patients Access to Care While Improving Quality and Access
5. Tips for Maintaining Your Physique While Enjoying Your Favorite Treats
6. AMA to Support Laws Against Text Messaging While Driving
7. This Thanksgiving Season, Lifespring Health is Helping You Donate While You Shop
8. Media Spotlight Shines on Dr. Siegals Cookie Diet While Major Study Reveals Doubling of U.S. Type II Diabetes Cases During Past Ten Years
9. While prevalent, sexual problems in women not always associated with distress
10. Credit Counseling Agency Helps Consumers Live Healthier While Becoming Financially Fit
11. Eating fish while pregnant, longer breastfeeding, lead to better infant development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... ... 20, 2017 , ... Houston dentist , Dr. Nazari, ... at his office, Antoine Dental Center. Emergency dentistry encompasses many treatments for emergencies ... risk for serious complications and often experience severe pain. Not only does prompt ...
(Date:2/20/2017)... ... February 20, 2017 , ... Florida Hospital ... a new ultrasound-enhanced thrombolysis machine, a state-of-the-art device that breaks up life-threatening blood ... the Pepin Family Foundation. , “We greatly appreciate this gift from Constellation Brands. ...
(Date:2/19/2017)... RI (PRWEB) , ... February 19, 2017 , ... ... is proven to result in better care, and MEDfx and the Delaware Health ... state of Delaware. , As the nation’s first state-wide health information exchange, DHIN ...
(Date:2/18/2017)... ... 2017 , ... Butler Mobility invited Ken Matthews to visit its manufacturing facility ... Ken was impressed with the safety and reliability of the Stannah Stairlift as well ... This endorsement by Ken Matthews can be heard on News Radio WHP 580 ...
(Date:2/18/2017)... ... 2017 , ... A new directory from the Senior Veterans ... connect elderly veterans of America's armed forces to a range of senior care ... on this year's increase in the Veterans Pension with Aid & Attendance for ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... FRANCISCO , February 20, 2017 ... expected to reach USD 58.4 billion by 2025, ... Research, Inc. The market is driven by technological ... serve future growth opportunities to the market. For ... with an aim of identifying emerging viruses and ...
(Date:2/20/2017)... LONDON , February 20, 2017 Acute, Chronic ... is expected to grow at a CAGR of 7% from 2016-2021 and ... a CAGR of 6% from 2016 to 2027. The market is estimated ... ... Read on to discover how you can exploit the future business ...
(Date:2/18/2017)... 17, 2017   Parker Waichman LLP, ... rights of victims injured by medical devices, comments ... call for better reporting. Congress required hospitals to ... concerns involving power morcellators and duodenoscopes prompted the ... how hospitals report injuries and deaths related to ...
Breaking Medicine Technology: