Navigation Links
High Doses of Vitamin C May Raise Risk of Kidney Stones
Date:2/5/2013

By Randy Dotinga
HealthDay Reporter

TUESDAY, Feb. 5 (HealthDay News) -- Men who take high doses of vitamin C may face double the risk of kidney stones than men who do not, new research says.

Although the finding doesn't directly prove that vitamin C is at fault, and the actual occurrence of kidney stones -- the tiny mass of crystals that can painfully clog the urinary tract -- remained fairly rare, the findings raise questions about whether large doses of the vitamin are dangerous to the body.

"It is important that the public is aware that there may be risks associated with taking high doses of vitamin C," said study co-author Agneta Akesson, an associate professor with the Karolinska Institute in Stockholm, Sweden. "Those with a history of kidney stones should consult their doctor before taking high-dose vitamin C supplements."

Researchers have suspected that large amounts of vitamin C may increase the risk of kidney stones because the body breaks down the vitamin into a substance called oxelate, a component of the stones, Akesson said.

In the new study, which was published online Feb. 4 in the journal JAMA Internal Medicine, researchers tracked more than 23,000 Swedish men who were between 45 and 79 years old in 1997. The researchers followed the men, who hadn't previously been diagnosed with kidney stones, until 2009.

About 900 of the men regularly took 1,000-milligram doses of vitamin C, and 31 of them (3 percent) developed kidney stones. Of the rest of the larger group, fewer than 2 percent developed kidney stones.

After the researchers adjusted their statistics so they wouldn't be skewed by factors such as high or low numbers of men of certain ages, education levels and body weights, the researchers found that those who took the high-dose supplements had an increased kidney stone risk of between 1.7 and 2.2 times.

It's easy to find vitamin C tablets in the 1,000-milligram size at American drugstores and health stores. The size provides much more vitamin C than the U.S. government's recommended daily allowance, which is 75 milligrams to 90 milligrams for most adults.

Akesson said there are no well-documented reasons for anyone to take such high doses of vitamin C. The study doesn't apply to vitamin C that people get from food, and the researchers did find that multivitamin supplements, which don't contain mega doses of vitamin C, didn't seem to boost the risk of kidney stones.

It's not clear if the same possible risk from mega doses would apply to women. The study didn't include women, and they typically face a much lower overall risk of kidney stones than men, Akesson said.

What's next?

Akesson said more research is needed to confirm the findings, and another expert added that there are not many reasons to take such high doses of the vitamin.

For now, "there are no clear reasons to take supplemental vitamin C if adequate vitamin C is consumed in the diet," said Dr. Gary Curhan, a professor of medicine at Harvard Medical School who has studied kidney problems. "Of note, we have found that higher vitamin C intake is associated with a reduced risk of gout, but this is not sufficient justification to take a supplement."

More information

For more about kidney stones, try the U.S. National Library of Medicine.

SOURCES: Agneta Akesson, Ph.D., associate professor, Karolinska Institute, Stockholm, Sweden; Gary Curhan, M.D., Sc.D., professor, medicine, Harvard Medical School, Boston; Feb. 4, 2013, JAMA Internal Medicine, online


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Identifying asthma patients who tolerate lower doses of steroids remains problematic
2. Higher Doses of Vitamin D Prevent Fractures in Older Women
3. Higher but not lower doses of vitamin D are effective in fracture risk reduction in older adults
4. Doctor Shopping Tied to Fatal Prescription Drug Overdoses
5. As painkiller overdoses mount, researchers outline effective approaches to curb epidemic
6. Philadelphia Malpractice Lawyers at Console & Hollawell Explore Negligence as Overdoses from Prescription Painkillers Now Kill More People than Heroin
7. Chemo Pills Effective, But Patients May Skip Doses
8. Vitamin E in diet protects against many cancers
9. Researchers determine vitamin D blood level for reducing major medical risks in older adults
10. Vitamin K2: New hope for Parkinsons patients?
11. Experts call for clinical trials to test non-skeletal benefits of vitamin D
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
High Doses of Vitamin C May Raise Risk of Kidney Stones
(Date:12/2/2016)... ... December 02, 2016 , ... Center for Autism and Related Disorders (CARD) ... by autism spectrum disorder (ASD) and other developmental disabilities. The group, which is being ... and other caregivers the opportunity to share stories and advice, seek help, and continue ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... California, will be included in the 2016 “Guide to America’s Top Plastic Surgeons” ... on the amalgamation of their education, experience, and professional associations. , One ...
(Date:12/2/2016)... ... December 02, 2016 , ... Universal Medical Systems, Inc. (UMS) ... first company to offer robotic imaging to veterinary medicine is sponsoring the appearance ... for the American Association of Equine Practitioners 62nd Annual Convention from December 4-6, ...
(Date:12/2/2016)... CA (PRWEB) , ... December 02, 2016 , ... ... care journeys, announced today that it has raised $6.0 million in an initial ... by Clarify Health’s conviction that patients and their caregivers can receive far better ...
(Date:11/30/2016)... ... November 30, 2016 , ... The Fertility Centers of ... a Cigna Infertility Center of Excellence. The Cigna Center of Excellence recognizes participating ... honor to be designated a Cigna Infertility Center of Excellence," said Fertility Centers ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... , Dec. 2, 2016  The Addiction ... the Academy of Managed Care Pharmacy (AMCP), has ... can better address the opioid addiction crisis, including ... Therapies (MAT). ATAG,s newly released paper, ... Access to Naloxone," addresses many issues around gaps ...
(Date:12/2/2016)... -- CVS Health Corporation (NYSE: CVS ) ... December 15, 2016, beginning at 8:00 a.m. (ET). Senior members ... in-depth review of the company,s strategies to drive long-term ... discuss 2017 earnings guidance during the event. ... be broadcast simultaneously on the Investor Relations portion of ...
(Date:12/2/2016)... JUNCTION, N.J. , Dec. 2, 2016   ... care immunotherapy leader commercializing its European Union approved ... critically-ill and cardiac surgery patients worldwide, announced that Dr. ... at the 9th Annual LD Micro Main Event ... th , 2016 at the Luxe Sunset Boulevard Hotel ...
Breaking Medicine Technology: