Navigation Links
High Doses of Vitamin C May Raise Risk of Kidney Stones
Date:2/5/2013

By Randy Dotinga
HealthDay Reporter

TUESDAY, Feb. 5 (HealthDay News) -- Men who take high doses of vitamin C may face double the risk of kidney stones than men who do not, new research says.

Although the finding doesn't directly prove that vitamin C is at fault, and the actual occurrence of kidney stones -- the tiny mass of crystals that can painfully clog the urinary tract -- remained fairly rare, the findings raise questions about whether large doses of the vitamin are dangerous to the body.

"It is important that the public is aware that there may be risks associated with taking high doses of vitamin C," said study co-author Agneta Akesson, an associate professor with the Karolinska Institute in Stockholm, Sweden. "Those with a history of kidney stones should consult their doctor before taking high-dose vitamin C supplements."

Researchers have suspected that large amounts of vitamin C may increase the risk of kidney stones because the body breaks down the vitamin into a substance called oxelate, a component of the stones, Akesson said.

In the new study, which was published online Feb. 4 in the journal JAMA Internal Medicine, researchers tracked more than 23,000 Swedish men who were between 45 and 79 years old in 1997. The researchers followed the men, who hadn't previously been diagnosed with kidney stones, until 2009.

About 900 of the men regularly took 1,000-milligram doses of vitamin C, and 31 of them (3 percent) developed kidney stones. Of the rest of the larger group, fewer than 2 percent developed kidney stones.

After the researchers adjusted their statistics so they wouldn't be skewed by factors such as high or low numbers of men of certain ages, education levels and body weights, the researchers found that those who took the high-dose supplements had an increased kidney stone risk of between 1.7 and 2.2 times.

It's easy to find vitamin C tablets in the 1,000-milligram size at American drugstores and health stores. The size provides much more vitamin C than the U.S. government's recommended daily allowance, which is 75 milligrams to 90 milligrams for most adults.

Akesson said there are no well-documented reasons for anyone to take such high doses of vitamin C. The study doesn't apply to vitamin C that people get from food, and the researchers did find that multivitamin supplements, which don't contain mega doses of vitamin C, didn't seem to boost the risk of kidney stones.

It's not clear if the same possible risk from mega doses would apply to women. The study didn't include women, and they typically face a much lower overall risk of kidney stones than men, Akesson said.

What's next?

Akesson said more research is needed to confirm the findings, and another expert added that there are not many reasons to take such high doses of the vitamin.

For now, "there are no clear reasons to take supplemental vitamin C if adequate vitamin C is consumed in the diet," said Dr. Gary Curhan, a professor of medicine at Harvard Medical School who has studied kidney problems. "Of note, we have found that higher vitamin C intake is associated with a reduced risk of gout, but this is not sufficient justification to take a supplement."

More information

For more about kidney stones, try the U.S. National Library of Medicine.

SOURCES: Agneta Akesson, Ph.D., associate professor, Karolinska Institute, Stockholm, Sweden; Gary Curhan, M.D., Sc.D., professor, medicine, Harvard Medical School, Boston; Feb. 4, 2013, JAMA Internal Medicine, online


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Identifying asthma patients who tolerate lower doses of steroids remains problematic
2. Higher Doses of Vitamin D Prevent Fractures in Older Women
3. Higher but not lower doses of vitamin D are effective in fracture risk reduction in older adults
4. Doctor Shopping Tied to Fatal Prescription Drug Overdoses
5. As painkiller overdoses mount, researchers outline effective approaches to curb epidemic
6. Philadelphia Malpractice Lawyers at Console & Hollawell Explore Negligence as Overdoses from Prescription Painkillers Now Kill More People than Heroin
7. Chemo Pills Effective, But Patients May Skip Doses
8. Vitamin E in diet protects against many cancers
9. Researchers determine vitamin D blood level for reducing major medical risks in older adults
10. Vitamin K2: New hope for Parkinsons patients?
11. Experts call for clinical trials to test non-skeletal benefits of vitamin D
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
High Doses of Vitamin C May Raise Risk of Kidney Stones
(Date:6/26/2016)... ... 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop ... The fitness app plans to fix the two major problems leading the fitness industry today:, ... all type program , They don’t eliminate all the reasons people quit their ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... ... ... Bruton Memorial Library on June 21 due to a possible lice infestation, as reported by ... lice: the parasite’s ability to live away from a human host, and to infest common ... the event that lice have simply gotten out of control. , As lice are a ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... ... the United States, named Dr. Sesan Ogunleye, as the Medical Director of its new ... the facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... 24, 2016 Research and Markets has ... Companion Diagnostic Tests" report to their offering. ... Diagnostics The World Market for Companion Diagnostics ... diagnostics. Market analysis in the report includes the following: ... Vitro Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/23/2016)... June 23, 2016  MedSource announced today that ... e-clinical software solution of choice.  This latest decision ... value to their clients by offering a state-of-the-art ... relationship establishes nowEDC as the EDC platform of ... full-service clients.  "nowEDC has long been a preferred ...
Breaking Medicine Technology: