Navigation Links
High-Dose Chemo Helps Beat Rare Brain Cancer
Date:1/30/2008

Many patients achieved long-term remission without radiation, study finds

WEDNESDAY, Jan. 30 (HealthDay News) -- Most people suffering from a rare brain cancer appear to benefit from high doses of the chemotherapy drug methotrexate, a small study finds.

Primary central nervous system lymphoma (PCNSL) is a type of non-Hodgkin lymphoma that affects the brain. Although it is typically very difficult to treat, it can be cured or sent into long remissions. Current treatment is often a combination of radiation and chemotherapy. Newer approaches involve giving chemotherapy first, and waiting on radiation until the results of chemotherapy are seen.

However, "A subset of these patients with a rare form of non-Hodgkin lymphoma appeared to be cured by chemotherapy alone," explained lead researcher Dr. Tracy Batchelor, from the Massachusetts General Hospital Cancer Center in Boston.

Batchelor, who is executive director of the Stephen E. & Catherine Pappas Center for Neuro-Oncology at the hospital, noted there are about 1,500 new cases of PCNSL diagnosed in the United States each year.

In the study, Batchelor's group treated 25 adults with newly diagnosed PCNSL with a high dose of methotrexate every two weeks for four months, or until there were no signs of the brain tumor. The patients were followed for a minimum of 6.5 years.

The report appears in the Jan. 29 issue of Neurology.

Batchelor's team found that 52 percent of the patients had a complete remission of their cancer and 40 percent had not had a relapse after seven years. Average survival of all patients who received methotrexate was 4.5 years, compared with one year among patients who had radiation therapy.

It's clear that methotrexate is the best drug to treat this tumor, Batchelor said. "The drug attacks cells that are dividing. Other drugs don't have as high a response rate," he explained.

Batchelor note
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. High-Dose Chemo Provides Little Benefit to Breast Cancer Patients
2. High-dose chemo and stem cell transplant shows little or no survival benefit for breast cancer
3. Explaining chemotherapy-associated nausea
4. Combined radiation seed, chemotherapy wafer implants show promise in treating cancerous brain tumors
5. ChemoCentryx Appoints Edward E. Penhoet, Ph.D., to Board of Directors
6. Class of Chemotherapy Drugs Helps Certain Breast Cancer Patients
7. Chemotherapy and tamoxifen reduce risk of second breast cancer
8. Modeling Simulation Predicts Potential Negative Impact on U.S. Blood Supply if ESA Use Limited for Chemotherapy-Induced Anemia
9. Gentler chemotherapy before stem cell transplant causes long-term remission of follicular lymphoma
10. Extracellular protein sensitizes ovarian cancer cells to chemotherapy
11. Chemoprevention, naturally: Findings on plant-derived cancer medicines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
High-Dose Chemo Helps Beat Rare Brain Cancer
(Date:7/12/2014)... (PRWEB) July 12, 2014 As reported in ... Institute of Standards and Technology), the June 25th, 2014 Supreme ... electronic discovery world. It was also met with ... depending on whether it was seen from an individual privacy ... much is fact, there is now precedent which will require ...
(Date:7/12/2014)... A recent article released by Seattle's well known plastic ... those seeking cosmetic surgical procedures in summer months . ... heat begins to enliven the rainy Pacific Northwest, many people ... they didn’t work out as much during the winter as ... surge of people eager to look their best for their ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Restore My ... Sen and Samantha Pearson, a couple boasting very impressive ... launch Restore My Vision Today as a way to ... ophthalmologists have become in their respective patients’ treatments ... privy to a “secret” trove of pertinent information relevant ...
(Date:7/12/2014)... 2014 The largest pure occupational medicine ... to announce that it will be opening its fifth ... will join four Atlanta-based Nova Medical Centers’ locations. The ... Deans Bridge Road, and will be open from 8:30 ... “With Nova’s treatment philosophy of rapid return-to-work and decreased ...
(Date:7/11/2014)... DressyQuinceanera.com, a well-known wedding dress manufacturer and retailer, has ... online category. Furthermore, the firm has announced that all ... to 62% off. , The brand new Quinceanera Dama ... quality and style. All items in the new collection ... the company’s other items: lace evening dresses, short bridesmaid ...
Breaking Medicine News(10 mins):Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 2Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 3Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 4Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 5Health News:Best Summer Cosmetic Surgeries Revealed in Article By Seattle Plastic Surgeon 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 3Health News:Nova Medical Centers To Open New Facility in Augusta, Georgia 2Health News:DressyQuinceanera.com: Beautiful Quinceanera Dama Dresses At Low Prices 2
... women's infant mortality rates in Florida is widening, Florida ... on Wednesday, the Tallahassee Democrat reports. ... Health Service division, the state's racial gap in infant ... are twice as likely to have premature babies in ...
... Japanese firm announced this week that it has developed ... significantly improve// the efficacy of chemotherapy drugs and reduce ... (NDT), the US subsidiary of Nitto Denko Corporation, says ... and biocompatible polymer material which can be loaded with ...
... The African Malaria Network Trust (AMANET) has received a ... & Melinda Gates// Foundation. ,According to the ... the four-year grant is aimed at strengthening institutional capacity ... ,It also aims at fostering and promoting discussion, ...
... drug Avastin has been tested for the first time against ... ,Duke University researchers used Avastin, known chemically as bevacizumab, ... recurrent brain tumors called gliomas. Good news -- the two ... any other therapy. ,Gliomas are mostly incurable in ...
... confirmed the presence of bird flu in their county. This ... ministry. ,The lethal H5N1 virus was found in ... was suspected, later it was diagnosed as the case of ... necessary precautions are being followed. ,Culling of birds ...
... stated a tobacco industry memo from 1969. For half a ... smoking and cancer. Now, with that effort long since failed, ... again attempting to manufacture doubt. ,"The tobacco industry ... saying that everyone knew but no one had proof," said ...
Cached Medicine News:Health News:New Cost-cutting Cancer Drug Delivery System 2Health News:New Cost-cutting Cancer Drug Delivery System 3Health News:Tobacco Companies Obstructed Science 2Health News:Tobacco Companies Obstructed Science 3
(Date:7/10/2014)... 10, 2014  RESMED INC. (NYSE: RMD ) ... fiscal year ended June 30, 2014 results on Thursday, July ... A press release with ResMed,s results will be issued after ... a webcast to discuss operating results and future outlook. ... p.m. US Pacific Time and the live webcast of the ...
(Date:7/10/2014)... 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... completed the sale to Galderma of all rights to ... by Valeant for $1.4 billion in cash, pursuant to ... completed its acquisition of Galderma. "We ... to a company that is firmly committed to the ...
(Date:7/10/2014)... Israel , July 10, 2014   ... Diabetes Management Solution, today announced the appointment of ... independent member of its Board of Directors. ... legal and business experience to LabStyle as an ... and legal and corporate governance expert. He currently ...
Breaking Medicine Technology:ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4
... Valeritas, Inc., a medical technology ... innovative drug delivery solutions, announced today that the ... company,s V-Go Disposable Insulin Delivery Device for use ... delivery of insulin in preset basal rates and ...
... Dehaier Medical Systems Ltd. (Nasdaq: DHRM ... in the development, assembly, marketing and sale of ... today announced that management will present at the ... (Logo: http://photos.prnewswire.com/prnh/20100422/CNTH001LOGO ) Rodman & ...
Cached Medicine Technology:Valeritas Receives FDA 510(k) Clearance for the V-Go™ Disposable Insulin Delivery Device for Use with NovoLog® 2Valeritas Receives FDA 510(k) Clearance for the V-Go™ Disposable Insulin Delivery Device for Use with NovoLog® 3Dehaier Medical Announces March Investor Presentations 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: