Navigation Links
High Cholesterol Might Be Linked to Alzheimer's Disease
Date:9/13/2011

By Randy Dotinga
HealthDay Reporter

MONDAY, Sept. 12 (HealthDay News) -- New research suggests that high cholesterol levels could boost the risk of Alzheimer's disease by creating more brain-clogging bits known as plaque.

The finding doesn't directly prove that high cholesterol causes Alzheimer's disease or that lowering it would reduce the risk. Also, researchers didn't find any link between high cholesterol and tangles, which also clog the brain in those with Alzheimer's.

Still, the findings add to previous research that has linked insulin resistance to Alzheimer's disease, said study author Dr. Kensuke Sasaki. Better control of both cholesterol levels and insulin resistance, both risk factors for heart disease, "might contribute to a strategy for the prevention of Alzheimer's disease," said Sasaki, an assistant professor of neuropathology at Kyushu University in Japan.

An estimated 5.4 million Americans have Alzheimer's disease, according to the Alzheimer's Association, and the number is expected to grow to 16 million by 2050 as the population ages. There's no known way to prevent Alzheimer's or cure it.

The researchers studied the brains of 147 people -- 76 men, 71 women -- who were residents of a Japanese town and alive in 1988 when they underwent clinical examinations. They all underwent autopsies between 1998 and 2003.

About one-third of them had been diagnosed with dementia during life, although they didn't show signs of it in 1988.

Compared with people with low cholesterol levels, those with high cholesterol levels were more likely to have the bits of protein in the brain known as plaques: 62 percent versus 86 percent, respectively.

But tangles, which are bits of another kind of protein, weren't more common in people with high cholesterol.

Dr. Marc L. Gordon, chief of neurology at the Zucker Hillside Hospital in Glen Oaks, N.Y., said the research is credible and intriguing. It adds to existing speculation that higher cholesterol levels in midlife, particularly of so-called "bad" cholesterol, boost the risk of Alzheimer's later, said Gordon, who's also an Alzheimer's researcher at the Feinstein Institute for Medical Research.

It's not clear how cholesterol may make plaques more common, Gordon said, although cholesterol is found in plaques. It's possible that high cholesterol could set off another process that causes Alzheimer's, he said, or that something else "predisposes you to be prone to Alzheimer's and raises your cholesterol level."

There's a twist: cholesterol levels and obesity appear to drop in people who have dementia, although that may have something to do with changes in their eating habits, Gordon noted.

The study is published in the Sept. 13 issue of the journal Neurology.

More information

For more about Alzheimer's disease, try the U.S. National Library of Medicine.

SOURCES: Kensuke Sasaki, M.D., assistant professor, neuropathology, Kyushu University, Fukuoka, Japan; Marc L. Gordon, M.D., chief, neurology, Zucker Hillside Hospital, and Alzheimer's researcher, The Feinstein Institute for Medical Research, Manhasset, N.Y.; Sept. 13, 2011, Neurology


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Drug Boosts Good Cholesterol in Study Patients
2. Researchers find process that clears cholesterol and could reverse major cause of heart attack
3. Certain Foods Said to Help Lower Bad Cholesterol
4. Childrens HIV Drugs May Cause High Cholesterol
5. Cholesterol-lowering drugs may help prevent recurrent strokes in younger people
6. Mail-order pharmacy for new statin prescriptions achieve better cholesterol control
7. Controversial Cholesterol Drug Might Lower Blood Sugar Levels in Diabetics
8. Scientists Discover Ultra-Bad Cholesterol
9. Experts Say Cholesterol Screenings Should Start in Childhood
10. Selenium Supplements Might Give Modest Benefit Against Cholesterol
11. Bad cholesterol not as bad as people think, shows Texas A&M study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
High Cholesterol Might Be Linked to Alzheimer's Disease
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating ... many ways they remain in the eye of the beholder, according to experts who ... of The American Journal of Managed Care. For the full issue, click here ...
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room ... Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of ...
(Date:6/24/2016)... ... , ... A recent article published June 14 on E Online ... on to state that individuals are now more comfortable seeking to undergo not only ... calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) ...
(Date:6/24/2016)... Fla. (PRWEB) , ... June 24, 2016 , ... Global ... Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition ... Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this year’s ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical ... the "Company"), which develops, markets and sells medical devices ... , signed a strategic cooperation agreement with Hongyuan ... "Hongyuan Supply Chain") on June 20, 2016, to develop ... the strategic cooperation agreement, Dehaier will leverage Hongyuan Supply ...
(Date:6/24/2016)... PUNE, India , June 24, 2016 ... "Pen Needles Market by Type (Standard Pen Needles, Safety ... 12mm), Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase ... published by MarketsandMarkets, This report studies the market for ... is expected to reach USD 2.81 Billion by 2021 ...
Breaking Medicine Technology: