Navigation Links
High Blood Pressure Likely in Alzheimer's Offspring

And hypertension could contribute to developing the brain disease, study finds

MONDAY, Nov. 2 (HealthDay News) -- Middle-aged adults whose parents have Alzheimer's disease are at increased risk for high blood pressure, evidence of arterial disease and markers of inflammation -- all of which may be associated with later development of Alzheimer's disease.

That's the finding of a study by researchers in the Netherlands who compared 206 adults in 92 families with a parental history of Alzheimer's and 200 adults in 97 families with no parental history of the disease.

The team at the VU University Medical Center in Amsterdam measured the participants' blood pressure, analyzed blood samples for genetic characteristics, cholesterol levels and levels of pro-inflammatory proteins called cytokines, and collected medical history and details about diet, exercise and stress levels.

The study found that 47 percent of adults with Alzheimer's-afflicted parents carried the gene (APOE e4) known to be associated with the disease, compared with 21 percent of those with no family history of Alzheimer's. Those with a family history had higher blood pressure readings, signs of arterial disease and higher levels of several different cytokines.

High blood cholesterol and glucose levels were not associated with parental Alzheimer's disease, according to the study, which is published in the November issue of the journal Archives of General Psychiatry.

"Our study shows that high blood pressure and an innate pro-inflammatory cytokine response in middle age significantly contribute to Alzheimer's disease," wrote Dr. Eric van Exel and colleagues. "As these risk factors cluster in families, it is important to realize that early interventions could prevent late-onset Alzheimer's disease. One could argue for a high-risk prevention strategy by identifying the offspring of patients with Alzheimer's disease, screening them for hypertension and vascular factors and implementing various (non)pharmacological health measures."

More information

The U.S. National Institute on Aging has more about Alzheimer's disease.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Nov. 2, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Specific antagonism lowers blood pressure
2. Restricting Blood Flow May Help Heart Bypass Patients
3. FDA Updates Prescription Guidelines for Blood Thinner
4. Doctors Often Miss High Blood Pressure in Kids
5. Back to School Means Return of School Blood Drives
6. Blood-flow detector software show promise in preventing brain damage
7. FDA Approves New Roche West Nile Virus Blood Screening Test
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Laser blasts viruses in blood
10. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
11. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... MPWH, the No.1 Herpes-only dating community in the world, revealed that ... ). More than 3.7 billion people under the age of 50 – or 67% ... WHO's first global estimates of HSV-1 infection . , "The data shocks us highly!" ...
(Date:11/27/2015)... ... , ... A simply groundbreaking television series, "Voices in America", which is hosted ... array of issues that are presently affecting Americans. Dedicated to providing the world with ... changing the subjects consumers focus on, one episode at a time. , In ...
(Date:11/27/2015)... ... November 27, 2015 , ... CBD College is proud to ... Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD College is honored ... one of twelve colleges and universities in the state of California make the cut. ...
(Date:11/27/2015)... ... November 27, 2015 , ... Avid collector, Andrew Hawley ... Michigan boxing style concert posters. This is one of Joplin's most famous and beautiful ... at the University of Michigan in Ann Arbor. The According to Hawley, "It is ...
(Date:11/26/2015)... NV (PRWEB) , ... November 26, 2015 , ... Inevitably ... strategy. Many customers choose to buy during the Black Friday and Cyber Monday ... Shoppers don’t need to search the Internet high and low to find the best ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 ... "Radioimmunoassay Market by Type (Reagents & ... Academics, Clinical Diagnostic Labs), Application (Research, Clinical ... 2020" report to their offering. ... addition of the "Radioimmunoassay Market by ...
(Date:11/25/2015)...  The total global healthcare industry is expected to grow ... Latin America has the highest projected growth at ... Japan ), is second with growth projected at 11.5%. ... healthcare expenditure. In 2013-2014, total government funded healthcare was nearly ... to 41.2% in 2013-2014. In real terms, out of pocket ...
(Date:11/25/2015)... 25, 2015  Linden Care, LLC, a retail specialty ... for patients suffering from chronic pain, said today that ... Restraining Order (TRO) enjoining Express Scripts from unilaterally terminating ... --> --> The company ... legal options. --> --> ...
Breaking Medicine Technology: